A5040053141- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Animal Virus Infections Studies
- Vaccine Coverage and Hesitancy
- Nanocluster Synthesis and Applications
- Mast cells and histamine
- SARS-CoV-2 detection and testing
- Bacterial Infections and Vaccines
- Complement system in diseases
- Thyroid Disorders and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Blood disorders and treatments
- Cytomegalovirus and herpesvirus research
- Autoimmune Bullous Skin Diseases
- Escherichia coli research studies
- COVID-19 and healthcare impacts
- Heparin-Induced Thrombocytopenia and Thrombosis
- Hematological disorders and diagnostics
- RNA regulation and disease
- Neurological Complications and Syndromes
Centre Hospitalier Régional de Namur
2024
Cliniques Universitaires Saint-Luc
2021-2023
Coronavirus disease 2019 , which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly life threatening in patients who are immunocompromised, including those with advanced chronic kidney (CKD) [1,2].Despite the implementation of a third dose messenger RNA (mRNA) vaccine, efficacy SARS-CoV-2 vaccination on humoral and cellular immunities reduced population CKD, resulting an increased incidence infection mortality, fully vaccinated [3].In this context,...
Evidence regarding the role of cellular immunity in protecting against COVID-19 is emerging. To better assess immune status, simple and robust assays measuring specific T-cell responses associated with humoral are needed. We aimed to evaluate Quan-T-Cell SARS-CoV-2 test for vaccinated healthy immunosuppressed subjects.
The first wave of coronavirus disease 2019 (COVID-19) was particularly dramatic for kidney transplant recipients (KTRs) around the world.1 A recent European registry study showed 28-day mortality and intensive care unit (ICU) admission rates at 22% 21%, respectively.2 In United States, a multicenter cohort revealed rate 18%.3 Fortunately, patients from our tertiary KT center were less impacted with ICU 11% 11%, respectively.4 Like many countries, Belgium is currently facing its COVID-19...
Coronavirus disease 2019 due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is particularly life threatening in patients with kidney failure under dialysis [1-3], mortality rate at 28 days of 21.2% the ERA-EDTA registry [4] and 25% ERACODA (European Renal Association COVID-19 Database) database [5].Vaccination campaigns have started most countries, a robust humoural response up 90% on haemodialysis (HD), albeit delayed rates below those achieved healthy controls [6-8], but...
We previously published disappointing results regarding the humoral response 28 d after second dose of BNT162b2 (Pfizer) vaccine in kidney transplant recipients (KTRs).1 The present article reports serological rate 90 injection using an immunoassay detecting antibody (Ab) against spike protein receptor-binding domain (RBD) (Elecsys Anti-SARS-CoV-2, Roche Diagnostics GmbH, Mannheim, Germany; positive threshold ≥0.8 U/mL; upper limit detection 250 U/mL). This work received institutional review...
A 68-year-old man with a medical history of hypertension was admitted to the emergency department for diffuse abdominal pain preceded by bloody diarrhea. Upon admission, neurological examination normal, but he suddenly developed left-sided hemiparesis. After normal brain computed tomography, intravenous thrombolysis administered suspicion ischemic stroke. In first laboratory investigations, hemoglobin 16.9 g/dL, platelets 121 × 109/L (150–450), and serum creatinine 1.17 mg/dL. By second...
The finding of white matter damage on brain magnetic resonance imaging may correspond to a wide variety etiologies. differential diagnosis be particularly difficultin immunocompromised patients with specific autoimmune disease or who are receiving medications after solid-organ transplant. Herein, we describe the case 22-year-old woman developed serious neurological complications an acute rejection kidney graft that she had received few months previous treat systemic lupus...