J Hrusková

ORCID: 0000-0003-3950-3927
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About
Contact & Profiles
Research Areas
  • Cardiovascular Health and Disease Prevention
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Viral Infections and Immunology Research
  • Respiratory viral infections research
  • Blood Pressure and Hypertension Studies
  • Non-Invasive Vital Sign Monitoring
  • Influenza Virus Research Studies
  • Diet and metabolism studies
  • Cardiovascular Disease and Adiposity
  • Pharmacology and Obesity Treatment
  • T-cell and Retrovirus Studies
  • Nutritional Studies and Diet
  • Immunodeficiency and Autoimmune Disorders
  • Cardiovascular Function and Risk Factors
  • Education, Psychology, and Social Research
  • Liver Disease Diagnosis and Treatment
  • Body Composition Measurement Techniques
  • Adipose Tissue and Metabolism
  • Transplantation: Methods and Outcomes
  • Animal Disease Management and Epidemiology
  • Hemodynamic Monitoring and Therapy
  • Virus-based gene therapy research
  • Vector-Borne Animal Diseases
  • Cancer, Lipids, and Metabolism

St. Anne's University Hospital Brno
2015-2021

University Hospital Brno
2015-2021

Masaryk University
2015-2021

International Clinical Research Center, St. Anne's University Hospital Brno
2020

National Institute Of Hygiene And Epidemiology
1978-1990

Charles University
1961-1967

Wojskowy Instytut Higieny i Epidemiologii
1967

Czech Academy of Sciences, Institute of Physiology
1966

Institute of Aviation Medicine
1966

Abstract Background The term arterial stiffness (ArSt) describes structural changes in wall related to the loss of elasticity and is known as an independent predictor cardiovascular diseases (CVD). evidence relating ArSt triglycerides (TG) shows contradictory results. This paper means survey association between high TG ArSt, utilizing cardio-ankle vascular index (CAVI). Methods Subjects aged 25 64 years from a random population-based sample were evaluated 2013 2016. Data questionnaires,...

10.1186/s12944-020-01345-0 article EN cc-by Lipids in Health and Disease 2020-07-15

Background: Intima-media thickness (IMT) has been proposed as a measurement of subclinical atherosclerosis and associated with cardiovascular disease (CVD). Epicardial adipose tissue (EAT) is fat depot between the pericardium myocardium coronary atherosclerosis. The relationship IMT EAT not reported before. We investigated thickness, IMT, CVD risk factors, ideal health (CVH) metrics using subjects from Kardiovize Brno 2030 cohort study, random urban sample population in Central Europe....

10.3390/jcm7050113 article EN Journal of Clinical Medicine 2018-05-13

Obesity and hypertension independently promote pathological left ventricular remodelling (LVR) hypertrophy (LVH), but to what extent they do so when not coexist is unclear. We used data from the Cardiovision Brno 2030 study assess-for first time in a region where no investigations have been previously carried out-the independent association of obesity with LV geometry, evaluate effects normal weight patients normotensive patients. Overall, 433 individuals, aged 25⁻65 years, history...

10.3390/jcm8030370 article EN Journal of Clinical Medicine 2019-03-15

Abstract Little is still known about the effect of dietary patterns on left ventricular hypertrophy (LVH). Here, we derived by principal component analysis (PCA) and evaluated their association with LV structure, function, remodelling. Our cross-sectional study included 438 members (aged 25–65 years; 59.1% women) Kardiovize Brno 2030 no history cardiovascular disease. Two were using PCA, namely prudent western. Primary outcomes echocardiographic parameters geometric patterns, such as...

10.1038/s41598-019-55529-5 article EN cc-by Scientific Reports 2019-12-16

Abstract Objective While circulating nucleosome levels are high in obese mouse models, it is unknown where these nucleosomes originate from and whether they a marker of cardio-metabolic health humans. Here, we aimed to determine an association exists between the risk developing obesity, metabolic syndrome (MetS) and/or dysfunctional cardiovascular performance. Methods We randomly selected 120 participants Kardiovize Brno 2030 study across three BMI strata: 18–25, 25–30, > 30. assessed...

10.1186/s13148-019-0797-8 article EN cc-by Clinical Epigenetics 2019-12-31

Diabetes mellitus 2 (DM2) is the seventh cause of death worldwide. One reasons late diagnosis vascular damage. Pulse wave velocity (PWV) has become an independent marker arterial stiffness and cardiovascular risk. Moreover, previous studies have shown importance beat-to-beat PWV measurement due to its variability among heart cycle. However, (PWVv) whole body hasn't been examined yet. We studied a group DM II heathy volunteers, investigate mean (PWVm) PWVv in different positions. left lower...

10.33549/physiolres.934594 article EN cc-by-nc Physiological Research 2021-01-22

Around 20-40% of heart transplant patients experience moderate to severe rejection within the first year after transplantation. Endomyocardial biopsy (EMB) is a gold standard for diagnosing rejection. There need non-invasive alternatives that allow early, safe and reliable diagnosis acute graft prior onset clinical symptoms.Our aim was investigate potential speckle tracking derived strain analysis in rejection.Patients indicated EMB consented trans-thoracic echocardiography examination (TTE)...

10.5507/bp.2015.020 article EN cc-by Biomedical Papers 2015-05-05
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