Mariangela Stinco

ORCID: 0000-0003-3970-5000
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About
Contact & Profiles
Research Areas
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Cystic Fibrosis Research Advances
  • Hepatitis Viruses Studies and Epidemiology
  • Thyroid Disorders and Treatments
  • Infant Nutrition and Health
  • Child Nutrition and Feeding Issues
  • Hernia repair and management
  • Liver Diseases and Immunity
  • Kawasaki Disease and Coronary Complications
  • Intestinal and Peritoneal Adhesions
  • Neonatal Respiratory Health Research
  • HIV/AIDS drug development and treatment
  • Neonatal Health and Biochemistry
  • Respiratory Support and Mechanisms
  • Orthopedic Infections and Treatments
  • Blood Coagulation and Thrombosis Mechanisms
  • Renal Transplantation Outcomes and Treatments
  • Streptococcal Infections and Treatments
  • COVID-19 Clinical Research Studies
  • Pediatric health and respiratory diseases
  • Respiratory viral infections research
  • Surgical Sutures and Adhesives
  • Pneumonia and Respiratory Infections

Meyer Children's Hospital
2020-2025

Austral University
2025

Consejo Nacional de Investigaciones Científicas y Técnicas
2025

Meyer Children's Hospital
2023-2024

Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024

University of Florence
2020-2022

Introduction: Human Bocavirus (HBoV) is mainly associated with respiratory tract infections. However, its role as pathogen not fully understood for a high co-infection rate in symptomatic patients and significant HBoV detection asymptomatic subjects. This study aimed to describe large cohort of children infection compare mono-infection co-infections. Methods: We retrospectively reviewed data from 165 admitted Meyer Children’s Hospital IRCCS March 2022 2023 the diagnosis infection, detected...

10.3390/pathogens13010055 article EN cc-by Pathogens 2024-01-06

Abstract In solid tumors, cancer cell survival is largely driven by hypoxia-induced metabolic changes, including the enhancement of glycolysis and extracellular acidification. This process facilitated enzymes such as carbonic anhydrase IX (CAIX), which upregulated under low oxygen tension to regulate pH exchanging H+ ions releasing lactate. These changes contribute an acidic tumor microenvironment (TME) that alters immune functionality, particularly recruiting tumor-associated macrophages...

10.1158/1538-7445.am2025-4852 article EN Cancer Research 2025-04-21

To prospectively describe the epidemiology and long-term outcome of childhood-acquired hepatitis C virus (HCV) infection in a large cohort children followed at single center.All with chronic HCV Liver Unit our tertiary Hospital Florence (Italy) from January 1, 1988, to September 30, 2021, were included analysis.The final sample consisted 163 (median age enrollment 4 years, interquartile range (IQR): 10; median last follow-up 14 IQR: 7). The duration was 86 months (IQR: 112). One hundred...

10.1097/mpg.0000000000003481 article EN Journal of Pediatric Gastroenterology and Nutrition 2022-06-01

Abstract The aims of this prospective study were as follows: (1) to describe the natural history chronic hepatitis B virus (HBV) infection in a large cohort untreated children followed at single centre and (2) evaluate whether or not new European Association for Study Liver (EASL) classification phases HBV adults can be used children. All who presented Unit our hospital from 1 January 1987 31 December 2019 diagnosed with enrolled. final sample consisted 152 median duration follow‐up was 83...

10.1111/jvh.13382 article EN Journal of Viral Hepatitis 2020-08-28

The Coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) have been variably associated with thromboembolic events (TEs) children. aim of our study was to assess the prevalence TEs hospitalized during a five-year period tertiary pediatric hospital, particularly patients COVID-19 MIS-C. Overall, 38 were discharged diagnosis TE: 20 pre-pandemic 18 pandemic period. same (0.08%) periods. occurrence higher or MIS-C (6/517, 1.16%) when compared without these...

10.3390/v15071554 article EN cc-by Viruses 2023-07-15

Protein-losing enteropathy (PLE) is a rare condition characterized by protein loss through the gastrointestinal tract, leading to hypo-proteinemia. Patients may be asymptomatic or present with variety of complications hypoproteinemia (e.g., oedema, ascites, pleural, and cardial effusions). We describe case report young girl suffering from behavioral disorder since childhood who presented generalized hypoproteinaemia, microcytic hypochromic anemia. In addition, had an intervention for jejunal...

10.3389/fped.2020.00082 article EN cc-by Frontiers in Pediatrics 2020-03-03

ABSTRACT Background & Aims Glecaprevir/Pibrentasvir (GLE/PIB) has been approved by the European Medicine Agency (EMA) and US Food Drug Administration (US‐FDA) for treatment of children adolescents from 3 years age with chronic hepatitis C virus (CHC) infection. The aim this study was to confirm real‐world effectiveness safety GLE/PIB in (3 < 18 old) CHC. Methods This prospective, multicentre involved 11 Italian centres. Children (from age) received a weight‐based dose (up 300/120 mg)...

10.1111/liv.16180 article EN cc-by-nc-nd Liver International 2024-11-21
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