A5100420472- Venous Thromboembolism Diagnosis and Management
- Acute Ischemic Stroke Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Atrial Fibrillation Management and Outcomes
- Smoking Behavior and Cessation
- Myasthenia Gravis and Thymoma
- Central Venous Catheters and Hemodialysis
- Cardiovascular Health and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Neuropathies and Disorders
- Lung Cancer Treatments and Mutations
- Cerebrovascular and genetic disorders
- Lung Cancer Research Studies
- Acute Myocardial Infarction Research
- Medical Research and Treatments
- Parkinson's Disease and Spinal Disorders
- Mobile Health and mHealth Applications
- Long-Term Effects of COVID-19
- Adrenal and Paraganglionic Tumors
- Methemoglobinemia and Tumor Lysis Syndrome
- FinTech, Crowdfunding, Digital Finance
- Dermatological and COVID-19 studies
- Neonatal Health and Biochemistry
- Urinary and Genital Oncology Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
Chongqing Medical University
2013-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2019-2024
China-Japan Friendship Hospital
2024
Deyang Stomatological Hospital
2023-2024
Pulmonary and Critical Care Associates
2023
Zhongshan Hospital
2023
Fudan University
2016-2023
Hubei University of Medicine
2023
Nanjing Medical University
2016-2017
Jiangsu Province Hospital
2016-2017
Abstract Anaplastic lymphoma kinase (ALK) rearrangements are present in about 5–6% of non-small cell lung cancer (NSCLC) cases and associated with increased risks central nervous system (CNS) involvement. Envonalkib, a novel ALK inhibitor, demonstrated promising anti-tumor activity safety advanced ALK-positive NSCLC the first-in-human phase I study. This III trial (ClinicalTrials.gov NCT04009317) investigated efficacy first-line envonalkib cases. Totally 264 participants were randomized 1:1...
Tobacco cessation is proven to be the most effective and cost-effective strategy for smokers reduce their risk of smoking-related disease premature death. Providing effective, efficient, safe, patient-centred tobacco treatment reach those who need them a significant challenge. To date, only few nationwide studies in China have assessed overall clinical care practice outcome cessation.This prospective, nationwide, multicenter, cohort study covering all Eastern China, Northwest Central North...
In order to detect cerebral microbleed more efficiently, we developed a novel computer-aided detection method based on susceptibility-weighted imaging. We enrolled five CADASIL patients and healthy controls. used 20x20 neighboring window generate samples each slice of the volumetric brain images. The sparse autoencoder (SAE) was unsupervised feature learning. Then, deep neural network established using learned features. results over 10x10-fold cross validation showed our yielded sensitivity...
Patients with minor ischemic stroke (MIS) have substantial disability rates at 90 days. Our study aimed to explore the association between systemic inflammation response index (SIRI) and 3-month functional outcomes in patients MIS.
Many smokers have not accessed professional smoking cessation assistance due to limited services. We developed a novel mHealth-based integrated modality for (WeChat + Quitline modality, WQ modality) and applied it large public welfare project (China Western-QUIT Program) in western China. This study evaluated the usage, acceptability, preliminary effectiveness of population China.A prospective cohort was conducted between April August 2021. Smokers or their relatives were recruited through...
Objective: the aim of this study was to compare AIMS65, Glasgow-Blatchford score (GBS) and Rockall for prediction risk in-hospital death among patients with upper gastrointestinal bleeding (UGIB). Methods: UGIB admitted ZhongDa hospital from June 2015 July 2017 were retrospectively collected. All assessed by GBS main outcomes mortality. Odds ratios (OR) 95 % confidence interval (CI) estimated assess association three scores using logistic regression models. Subsequently, their stratification...
Catheter-directed thrombolysis (CDT) has been a mainstay in treating deep venous thrombosis (DVT). However, the optimal dosage of thrombolytic agent is still controversial. The goal this study was to evaluate safety and efficacy low urokinase with CDT for DVT.A retrospective analysis performed using data from total 427 patients DVT treated our single center between July 2009 December 2012. Early assessed thrombus score based on daily venography. therapeutic evaluated by adverse events. A...
Abstract Background The association of clinical risk factors, in particular deep vein thrombosis (DVT), with stratification for pulmonary embolism (PE) remains to be identified. We therefore aimed establish the relationship between PE patients and DVT lower extremities. Methods In this retrospective study, 93 out 485 uncompleted data were excluded, resulting 392 included analysis. Based on ESC criteria, 24, 171, 197 categorized into high (6.1%), intermediate (43.6%), low (50.3%) subgroups,...
To investigate the protective role of Sijunzi decoction in neuromuscular junction (NMJ) and muscle cell mitochondria ultrastructure; as well its effects on amount adenosine triphosphate (ATP) activities mitochondrial respiratory chain complexes I, II, III, IV autoimmune myasthenia gravis rats.An experimental (EAMG) rat model was established by inoculating rats with acetylcholine receptors extracted from Torpedo. Rats were divided into three groups: model, prednisone, decoction, fed...
Renal function is associated with prognoses for acute pulmonary embolism (PE).To investigate the application of anticoagulants and dosage LMWH among patients renal insufficiency (RI), association between LWMH patients' in-hospital outcomes.Adult diagnosed non-high risk PE from 2009 to 2015, available data creatinine clearance (CCr) were enrolled a multicenter registry in China. (RI) was defined as CCr < 60 ml/min. converted into IU/kg daily dose presented adjusted (≤ 100 IU/kg/day)...
<title>Abstract</title> Background Renal function affects outcomes of acute pulmonary embolism (PE). We aimed to find an optimal method renal assessment for PE patients, by comparing the prognosis value estimated kidney injury (AKI) and glomerular filtration rate (eGFR) on hospitalized patients. Methods Adult patients diagnosed from 2009 2015 with available data serum creatine (SCr) were enrolled a nationwide, multicenter registry in China (CURES registry). Patients high-risk excluded. eGFR...
To assess the association between carotid artery plaques and risk of incident intracerebral hemorrhage (ICH) event in high-risk individuals for stroke.We conducted a population-based cohort study using longitudinal participant-level data multicenter, cross-sectional survey southwestern China. 2644 participants stroke were enrolled year 2015. The primary outcome was new-onset ICH events during five-year follow-up period. Multivariate logistic regression performed to identify plaque ICH....
Vesicoureteral reflux (VUR) is the commonest urinary tract diseases in children. It predisposes subjects to acute pyelonephritis, and most important risk factor for renal scars formation after infections Up now, controversies still exist on diagnosis treatment of VUR, mainly focusing which children should be assessed existence receive what kind once VUR recognized. In research its pathogenic mechanisms, has been found a genetic disorder with features racial differences, heterogeneity, etc....
Objective To improve the diagnosis consciousness of pulmonary thromboembolism (PTE) atypical manifestations and unknown embolus source.Methods One patient with portal vein superior mesenteric thrombosis combined PTE after splenectomy was analyzed,and related literatures were reviewed.Results Patients hepatocirrhosis would develop easily splenectomy,such as thrombosis,mesenteric PTE.Appropriate treatment should be considered according to liver function bleeding risk.Anticoagulant therapy...