A5037485652- Legume Nitrogen Fixing Symbiosis
- Flavonoids in Medical Research
- Plant biochemistry and biosynthesis
- Plant nutrient uptake and metabolism
- Histone Deacetylase Inhibitors Research
- Medicinal Plant Pharmacodynamics Research
- Chromatography in Natural Products
- Phytochemistry and biological activity of medicinal plants
- Natural product bioactivities and synthesis
- PARP inhibition in cancer therapy
- Plant Micronutrient Interactions and Effects
- Signaling Pathways in Disease
Oil Crops Research Institute
2020
Chinese Academy of Agricultural Sciences
2020
Ministry of Agriculture and Rural Affairs
2020
Huadong Hospital
2016-2019
Fudan University
2016-2019
Abstract Colon cancer is a leading cause of cancer-related deaths worldwide. The epithelial-mesenchymal transition (EMT) plays an important role in tumor metastasis colon cancer. We first evaluated the effects EMT-related transcription factors on prognosis through analysis data obtained from Cancer Genome Atlas (TCGA). And then we screened series Chinese medicine monomers to find effect EMT inhibitors. First, Snail more for prognosis, compared with Twist and Slug. Then, found that apigenin...
Abstract Background High-affinity nitrate transporter 2 ( NRT2 ) genes have been implicated in absorption and remobilization under nitrogen (N) starvation stress many plant species, yet little is known about this gene family respond to various stresses often occurs the production of rapeseed Brassica napus L.). Results This report details identification 17 members rapeseed, as well as, assessment their expression profiles using RNA-seq analysis qRT-PCR assays. In study, all BnNRT2. 1...
Colorectal cancer (CRC), a commonly occurring malignant tumor in the gastrointestinal tract, is third leading cause of cancer‑related deaths worldwide. FK506‑binding proteins (FKBPs) comprise an immunophilin family that are involved carcinogenesis, progression and chemoresistance cancers, including CRC. FKBP3 (also known as FKBP25) nuclear protein member FKBP correlated with activity histone deacetylase 2 (HDAC2). However, role HDAC2 oxaliplatin resistance CRC potential molecular mechanisms...
Nowadays, chemotherapy is still the main effective treatment for cancer. Herb prescriptions containing Pogostemon cablin Benth (also known as “Guang-Huo-Xiang”) have been widely used in Chinese medicine today. In our research, we found that patchouli alcohol, a compound isolated from oil of , exerted antitumor ability against human lung cancer A549 cells both vitro and vivo . MTT assay was to assess cell viability. Hoechst 33342 staining TUNEL cover glass provided visual evidence apoptosis....