- Breast Cancer Treatment Studies
- Nasal Surgery and Airway Studies
- Reconstructive Facial Surgery Techniques
- Head and Neck Surgical Oncology
- Cancer Immunotherapy and Biomarkers
- Spectroscopy and Chemometric Analyses
- Obstructive Sleep Apnea Research
- Global Educational Reforms and Inequalities
- Glycosylation and Glycoproteins Research
- HER2/EGFR in Cancer Research
- Smart Agriculture and AI
- Cancer Genomics and Diagnostics
- Organ Transplantation Techniques and Outcomes
- Genomics and Phylogenetic Studies
- Breast Implant and Reconstruction
- Reconstructive Surgery and Microvascular Techniques
- Cleft Lip and Palate Research
- Neuroscience of respiration and sleep
- Head and Neck Cancer Studies
- Sinusitis and nasal conditions
- Ear Surgery and Otitis Media
- Transcranial Magnetic Stimulation Studies
- Liver Disease and Transplantation
- Education and Learning Interventions
- Fungal Infections and Studies
Chonnam National University Hospital
2024
University of Ulsan
2011-2023
Ulsan College
2006-2023
Asan Medical Center
2011-2023
University Hospitals of Cleveland
2022
Chuncheon Sacred Heart Hospital
2016-2021
Hallym University
2016-2021
Cheongju National University of Education
2021
CHA University
2018-2020
Jeonbuk National University
2018-2019
Meteorin-like (metrnl) is a recently identified adipomyokine that beneficially affects glucose metabolism; however, its underlying mechanism of action not completely understood. We here show the level metrnl increases in vitro under electrical pulse stimulation and vivo exercised mice, suggesting secreted during muscle contractions. In addition, uptake via calcium-dependent AMPKα2 pathway skeletal cells phosphorylation HDAC5, transcriptional repressor GLUT4, an AMPKα2-dependent manner....
Abstract Sealants are useful as agents that can prevent the leakage of gas or nonclotting fluids from damaged tissues and blood vascular system following injury repair. Various formulations for sealants have been developed applied clinically, but problems still remain in terms biocompatibility issues, long crosslinking times low adhesive properties. Herein, to address these we report a methacrylated silk fibroin sealant (Sil-MAS) with rapidly crosslinkable, highly biocompatible properties...
To describe the aesthetic and clinical outcomes following rhinoplasty using autologous costal cartilage, which is considered best graft material for requiring major reconstruction. Few studies have examined cartilage.A retrospective review of data from 108 patients who underwent cartilage between April 2006 to May 2011. The study population consisted 81 male 27 female (mean age, 33.0 years). Each patient self-assessed their subjective satisfaction, 2 independent surgeons assessed...
Although scholars have carried out comprehensive research on the 1980 "Gwangju Democratization Movement" (GDM) and 1987 "June Democratic Struggle," they notably overlooked exploring role of Protestant leaders throughout these crucial times in South Korea's modern era. The lack this data academic literature extremely limits our knowledge greater sociopolitical aspects that influenced movements. Hence, major goal is to address by assessing Pastor Namju Byun's stewardship highlighting...
To describe the aesthetic and clinical outcomes following rhinoplasty using autologous costal cartilage, which is considered best graft material for requiring major reconstruction. Few studies have examined cartilage. A retrospective review of data from 108 patients who underwent cartilage between April 2006 to May 2011. The study population consisted 81 male 27 female (mean age, 33.0 years). Each patient self-assessed their subjective satisfaction, 2 independent surgeons assessed...
Objectives To reduce the mastoid cavity‐associated problems secondary to canal wall down mastoidectomy, we designed a new surgical procedure that includes reconstruction using free‐floating cartilages and double musculoperiosteal flaps. Study Design Retrospective study. Materials methods Thirty‐three patients were enrolled in this Preoperative postoperative pure tone audiometry/speech discrimination score status (complications EAC status) analyzed. Results Air conduction thresholds...
Objective/Hypothesis For dorsal augmentation in rhinoplasty, autologous costal cartilage can be used many different forms, including its crushed form. While only few studies have reported the outcome of using cartilage, current study aims to evaluate such usage. Study Design Retrospective chart review. Methods The records 38 patients were reviewed retrospectively. period was from 2006 2016. All enrolled underwent rhinoplasty that includes cartilage. Three facial plastic surgeons evaluated...
Cell surface glycans are often terminated by sialic acid, which is incorporated onto sugar acceptors sialyltransferases. The crystal structure of the GT family 42 Campylobacter jejuni α-2,3/2,8-sialyltransferase (CstII) provides key insights into sialyl-transfer mechanism, including tentative identification His188 as catalytic base. In support this hypothesis, CstII-H188A mutant able to catalyze sialyl transfer from CMP-Neu5Ac added anions such azide and formate but not its natural acceptor...
Localized radiotherapy (RT) can cause immune dysfunction. Bojungikki-tang is known to restore function. We investigated the absolute counts and percentages of peripheral blood (PB) lymphocyte subtypes in end stage cancer patients before after RT oral administration water extract (BJITE) evaluate changes mediated by BJITE. Absolute subsets were determined whole using TetraONE System (Beckman Coulter, USA). Flow cytometry results compared numbers CD3+, CD4+, CD8+ T cells CD19+ B decreased...
The neuroinvasive pathogen Neisseria meningitidis has 13 capsular serogroups, but the majority of disease is caused by only 5 these. Groups B, C, Y, and W-135 all display a polymeric sialic acid-containing capsule that provides means for bacteria to evade immune response during infection mimicking host cell surface structures. These capsules in serogroups can be further acetylated acid-specific O-acetyltransferase, modification correlates with decreased immunoreactivity increased virulence....
The Neisseria meningitidis sialic acid synthase (NeuB) catalyzes the metal-dependent condensation of N-acetylmannosamine (ManNAc) and phosphoenolpyruvate (PEP) to generate N-acetylneuraminic (NeuAc or acid). N. is a causative agent meningitis produces capsular polysaccharide comprised polysialic acid. This allows it evade immune system host by an act molecular mimicry. work describes synthesis characterization first potent inhibitor synthase. stable deoxy analogue tetrahedral intermediate...
To increase healing rate of tympanic membrane (TM) perforations, patching procedure has been commonly conducted. Biocompatible, biodegradable materials which is not limited across cultures needed. The authors evaluated the effectiveness novel transparent duck's feet collagen film (DCF) patch in acute traumatic TM perforation. This was compared with spontaneous and paper patching. Cell proliferation features were observed DCF patches. Forty-eight TMs 24 rats used for animal experiment,...