J Šmejkalová

ORCID: 0000-0003-3977-0478
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Education, Psychology, and Social Research
  • Dental Health and Care Utilization
  • Psoriasis: Treatment and Pathogenesis
  • Multiple Myeloma Research and Treatments
  • Immunotherapy and Immune Responses
  • Carcinogens and Genotoxicity Assessment
  • Human Health and Disease
  • Oral Health Pathology and Treatment
  • Drug-Induced Hepatotoxicity and Protection
  • Liver Disease Diagnosis and Treatment
  • Estrogen and related hormone effects
  • Glycosylation and Glycoproteins Research
  • Dermatology and Skin Diseases
  • Monoclonal and Polyclonal Antibodies Research
  • Digestive system and related health
  • Spaceflight effects on biology
  • Public health and occupational medicine
  • Occupational and environmental lung diseases
  • School Health and Nursing Education
  • Allergic Rhinitis and Sensitization
  • HIV/AIDS oral health manifestations
  • Acute Lymphoblastic Leukemia research
  • Eicosanoids and Hypertension Pharmacology
  • Immunotoxicology and immune responses

Charles University
2006-2022

University Hospital Hradec Králové
2007-2022

Ministère de la Santé et de l'Hygiène Publique
1990

Jazykovědné Sdružení České Republiky
1989

The purpose of the study was to describe occurrence most common complaints related MSDs in Czech dentists and assess risk factors affecting them. A questionnaire survey 581 (the response rate 72.6%) conducted 2011. ascertained general information about respondents, their work habits environment along with musculoskeletal disorders. respondents filled out questionnaires during educational events organized by Dental Chamber. At least mild difficulties associated motoric system were reported...

10.2486/indhealth.2013-0141 article EN Industrial Health 2014-10-16

This article reviewed smoking related systemic diseases and oral diseases. Smoking is to lung cancer, cardiovascular many other Cigarette smoke affects the cavity first, so it evident that has negative influences on cavity, for example, staining of teeth dental restorations, wound healing, reduction ability smell taste, development such as periodontitis, smoker’s palate, melanosis, hairy tongue, leukoplakia, candidiasis implant survival rate. The also discusses relationship between caries in detail.

10.14712/18059694.2017.76 article EN cc-by Acta Medica (Hradec Kralove Czech Republic) 2007-01-01

This review article describes different forms of tobacco usage and its direct relationship with the prevalence dental caries. Smoking along co-existing factors like old age, bad oral hygiene habits, food limited preventive visits over all health standards, can be associated high caries incidence. However, a etiological is lacking. Environmental smoke (ETS) causes in children but no studies have been reported adults. Existing findings are not sufficient conclusive enough to confirm that ETS...

10.21101/cejph.a3431 article EN Central European Journal of Public Health 2007-09-01

This cross-sectional study was aimed at possible relationships between tobacco habits and selected behavior characteristics in an adult sample from India. Contemporaneous clinical examination comprised intra-oral with specific emphasise to dental caries status the form of DMFT (Decayed, Missing, Filled Teeth) index. The 805 subjects age group 30 69 years (72% males 28% females). participants were divided into regular smokers, occasional ex-smokers, chewers non-tobacco users. highest...

10.21101/cejph.a3448 article EN Central European Journal of Public Health 2008-06-01

Objective: The purpose of this study was to assess the oral health-related quality life in Czech population. Methods: Data were collected from 1,380 subjects aged 30 69 years attending Department Dentistry, Medical Faculty Charles University Hradec Králové or three private dental practitioners collaborating on study. Oral measured with Health Impact Profile (OHIP-14) questionnaire that translated Czech. OHIP-14 scores assessed relation chosen clinical and sociodemographic characteristics...

10.21101/cejph.a3578 article EN Central European Journal of Public Health 2010-06-01

Tobacco is one of the most important risk factors for oral diseases, including cancer, mucosal lesions and periodontal diseases. There substantial evidence suggesting that diseases increases with frequent use tobacco quitting smoking results in reduced risk. In this article, influence cigarette on periodontium will be discussed, giving importance to effects immune responses, alveolar bone loss, pathogens briefly outlining negative wound healing treatment procedures.

10.14712/18059694.2017.52 article EN cc-by Acta Medica (Hradec Kralove Czech Republic) 2007-01-01

Objective: Early morning shifts have a negative effect on the hypothalamic-pituitary-adrenal axis. The aim of this study was to comprehensively assess extent occupational stress in early shift workers car industry by using salivary cortisol as an objective marker during workday and day off. Methods: For cross-sectional epidemiological type study, survey included 55 suitable volunteers from industry. Five saliva samples were collected according following schedule: one work morning, 6 a.m. - 2...

10.21101/cejph.a5092 article EN Central European Journal of Public Health 2018-06-30

The welding processes belong among the important sources of occupational pollutions. fumes are ranked, according to classification IARC (International Agency for Research on Cancer), into group 2B. In our study we have performed investigation twenty men (exposed group) working in stainless steel industrial (11 welders and 9 grinders, average age was 31 years, 55% smokers, time period exposure 8 years). concentrations chromium (0.557-16.343 mg/m3) nickel (0.340-10.129 atmosphere highly...

10.14712/18059694.2019.5 article EN cc-by Acta Medica (Hradec Kralove Czech Republic) 2003-01-01

Biochemical markers of kidney damage were examined in 52 male stainless steel welders (manual metal arc welding) exposed to chromium and nickel. No difference was found the mean urinary excretion total proteins, albumin, protein 1, transferrin, retinol-binding protein, lactate dehydrogenase, lysozyme, or beta-N-acetylglucosaminidase a comparison with matched referents. Beta 2-microglobulin slightly increased those concentration greater than 64.5 nmol.mmol-1 creatinine. The prevalences...

10.5271/sjweh.1581 article EN cc-by Scandinavian Journal of Work Environment & Health 1992-08-01

Goeckerman's therapy (GT), which combines exposure to coal tar (polycyclic aromatic hydrocarbons - PAHs) and UV radiation (UV) is often used as the first option for treatment of psoriasis. However, PAHs represent mutagenic, carcinogenic immunotoxic agents. Therefore GT can a health risk patients. The group under observation consisted thirty patients undergoing GT. Before after treatment, blood samples were collected chromosomal aberrations selected immunological markers determined....

10.33549/physiolres.930787 article EN cc-by-nc Physiological Research 2006-01-01

The two main aims of our study were to assess the quality life (QOL) patients with moderate or severe psoriasis treated by Goeckerman therapy and compare QOL on date admission 1 month after their discharge.We performed a prospective 51 for chronic plaque regimen (GR). area involvement severity was measured using Psoriasis Area Severity Index (PASI). Patients' health-related evaluated Disability (PDI).In we demonstrated that this sample forms relatively good; an average PDI value day 9.02,...

10.21101/cejph.a5611 article EN Central European Journal of Public Health 2020-09-30

Objective: The aim of this study is to monitor and analyze the influence chosen family indicators related alcohol consumption experience drunkenness in a representative sample Czech children. Methods: Data for our work were obtained from Health Behaviour School Aged Children (HBSC) - World Organization (WHO) cross national study. consisted 4,293 children aged 11, 13 15 years. collection was conducted June 2010 88 randomly selected schools Republic using standardized questionnaires....

10.21101/cejph.a4381 article EN Central European Journal of Public Health 2017-03-01

Psoriasis and metabolic syndrome (MetS), a common comorbidity of psoriasis, are associated with mild chronic systemic inflammation that increases oxidative stress causes cell tissue damage. At the cellular level, chromosomal DNA damage has been documented, thus confirming their genotoxic effect. The main objective our study was to show potential determine whether presence both pathologies compared psoriasis alone evaluate there correlations between selected parameters aberrations in patients...

10.3390/metabo12080688 article EN cc-by Metabolites 2022-07-26

Abstract The aim of the present study was to establish relationship between tobacco use and periodontal health in an adult sample India. A cross-sectional population-based conducted a province southern total 805 subjects ages 30 69 years were interviewed, clinical examinations made by three cooperating dentists. examiners recorded oral mucosal findings, gingivitis, Community Periodontal Index Treatment Needs index using WHO-621 Trinity probe. Among participants, 72% males 28% females....

10.2478/s11536-007-0057-8 article EN cc-by-nc-nd Open Medicine 2007-12-07

Abstract Polycyclic aromatic hydrocarbons (PAHs) and ultraviolet radiation (UV) represent genotoxic factors that commonly occur in the living working environment. The dermal form of exposure represents a significant part total load dangerous chemical physical environmental to which an organism is subjected. However, simultaneous exposures PAHs (pharmaceutical crude coal tar [CCT]) UV (UVA UVB) also have therapeutic uses. A typical example Goeckerman therapy (GT) for psoriasis. question...

10.1002/jat.4074 article EN Journal of Applied Toxicology 2020-10-04
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