Radovan Slezák

ORCID: 0000-0002-4922-5062
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Research Areas
  • Oral Health Pathology and Treatment
  • Salivary Gland Disorders and Functions
  • Dental Implant Techniques and Outcomes
  • Oral and gingival health research
  • Oral and Maxillofacial Pathology
  • Dental Radiography and Imaging
  • Oral microbiology and periodontitis research
  • Salivary Gland Tumors Diagnosis and Treatment
  • Autoimmune Bullous Skin Diseases
  • Diabetes and associated disorders
  • Head and Neck Cancer Studies
  • Dental materials and restorations
  • Dental Health and Care Utilization
  • Herpesvirus Infections and Treatments
  • Inflammasome and immune disorders
  • Preterm Birth and Chorioamnionitis
  • Periodontal Regeneration and Treatments
  • Soft tissue tumor case studies
  • Antifungal resistance and susceptibility
  • Endodontics and Root Canal Treatments
  • Orthopaedic implants and arthroplasty
  • dental development and anomalies
  • Photodynamic Therapy Research Studies
  • Neonatal and Maternal Infections
  • Immune Response and Inflammation

University Hospital Hradec Králové
2013-2024

Charles University
2014-2024

University of Hradec Králové
1991-2024

Ocní klinika
2011-2013

Abstract Photodynamic antimicrobial therapy (PACT) involves the utilisation of photosensitizers activated by exposure to visible light in order eradicate microbes (this method has already been applied photodynamic tumours). effect particular photosensitive substance (PS) is attributed its ability penetrate susceptible microorganisms, absorb certain wavelength, and generate reactive cytotoxic oxygen products. The target microorganisms for photoinactivation are bacteria, fungi, viruses...

10.2478/s11535-010-0032-2 article EN cc-by-nc-nd Open Life Sciences 2010-04-29

The purpose of this study was to determine the accuracy panoramic radiography in identification maxillary sinus septa. Out 68 sinuses were radiographically examined using both and computerized tomographic radiographs (CT scan). Using CT scan, 24 (35.9%) out cases maxillae showed at least one septum, 22 (32.3%) whereas two (2.9%) exhibited Panoramic radiograph led a false diagnosis regarding presence or absence septa 18 (26.5%). On other hand, they gave negative 12 (50%). There fully...

10.14712/18059694.2019.76 article EN cc-by Acta Medica (Hradec Kralove Czech Republic) 2002-01-01

Introduction: Oral lichen planus (OLP) is a chronic inflammatory disease with an unknown etiology rating among oral potentially malignant disorder. The aim of the study was to determine epidemiological and clinical characteristics patients OLP rate transformation. Patients methods: Data were obtained from medical records 271 referred Medicine Unit at University Hospital in Hradec Králové diagnosed period 2003–2020. retrospectively analyzed. following data retrieved charts: gender, age,...

10.3390/ijerph18126525 article EN International Journal of Environmental Research and Public Health 2021-06-17

Introduction: Oral Lichen planus (OLP) is chronic inflammatory oral mucosal disease of unknown etiology. Basement membrane damage and T‑cell migration in OLP may be mediated by matrix metalloproteinases (MMPs). We examined the expression metalloproteinase 9 to support this hypothesis. Materials methods: The study population consisted 71 patients with 10 control fibromas. Indirect immunohistochemistry was used for detection MMP (polyclonal rabbit anti‑human antibody). Results: In all cases...

10.14712/18059694.2015.70 article EN cc-by Acta Medica (Hradec Kralove Czech Republic) 2012-01-01

Objective: The purpose of this study was to assess the oral health-related quality life in Czech population. Methods: Data were collected from 1,380 subjects aged 30 69 years attending Department Dentistry, Medical Faculty Charles University Hradec Králové or three private dental practitioners collaborating on study. Oral measured with Health Impact Profile (OHIP-14) questionnaire that translated Czech. OHIP-14 scores assessed relation chosen clinical and sociodemographic characteristics...

10.21101/cejph.a3578 article EN Central European Journal of Public Health 2010-06-01

Abstract Objective Periodontal disease is a possible contributing factor to preterm delivery. The aim of this study was compare the periodontal status women with prelabour rupture membranes ( PPROM ) and uncomplicated singleton pregnancies. Patients Methods Seventy‐eight at gestational ages between 24 + 0 36 6 weeks 77 healthy pregnancies, matched for age sampling without birth, were included in study. All underwent evaluation oral hygiene status. Results Women had higher gingival plaque...

10.1111/jcpe.13067 article EN Journal Of Clinical Periodontology 2019-01-14

Sarcoidosis is a common multisystemic granulomatous disease characterized by the formation of nonnecrotizing epithelioid granulomas in various body organs. The most commonly affected organs head-and-neck region include salivary glands and cervical lymph nodes. Involvement oral mucosa very rare. purpose this report to present an atypical manifestation sarcoidosis with ulcerations buccal 59-year-old female.

10.4103/jisp.jisp_378_16 article EN cc-by-nc-sa Journal of Indian Society of Periodontology 2016-01-01

Předmět sdělení: Primární Sjögrenův syndrom je progresivní autoimunitní onemocnění, které postihuje převážně ženy ve středním věku, typicky čtvrtém až šestém desetiletí života. Je třetí nejčastější chorobou v současné populaci po revmatoidní artritidě a systémovém lupus erythematodes. Příčina onemocnění není plně objasněna, ale předpokládá se kombinace vrozené dispozice, vlivu pohlavních hormonů, infekčních faktorů životního prostředí. Aktuální diagnostická kritéria jsou z roku 2016;...

10.51479/cspzl.2018.005 article CS cc-by-nc Česká stomatologie a praktické zubní lékařství 2018-06-01

Periodontal disease is frequently suggested as a possible causal factor for preterm delivery. The link between periodontal and delivery translocation of periopathogenic bacteria to the placenta amniotic fluid well systemic response this chronic inflammatory disease. However, there lack information on whether an association clinical status in women with prelabor rupture membranes (PPROM) presence microbial invasion cavity (MIAC) intra-amniotic inflammation (IAI). Therefore, main aim study was...

10.1080/14767058.2017.1358265 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2017-07-20

Introduction: Oral manifestations of deficiency iron, vitamin B12 and folic acid are thought to be common. Prevalence these deficiencies among patients with compatible symptoms is not well known. The goal this study was summarize evidence from a dental practice in presenting oral manifestations. Methods: 250 who presented burning mouth syndrome, angular cheilitis, recurrent aphthous stomatitis, papillar atrophy the tongue dorsum or mucosal erythema were identified. Patients underwent...

10.14712/18059694.2020.25 article EN cc-by Acta Medica (Hradec Kralove Czech Republic) 2020-01-01

Hematopoietic stem cell transplantation (HSCT) can induce serious oral complications, including mucositis (OM). The presence of periodontal inflammation before HSCT is believed to be associated with OM. aim our study was determine the prevalence and severity OM in patients undergoing its relation status.This a retrospective who underwent detailed dental examination between 2007 2015. status all evaluated by clinical radiographic prior HSCT. Oral health assessed gingival index, community...

10.3390/jcm10245790 article EN Journal of Clinical Medicine 2021-12-10

To analyse the dimensions of interantral bone available for dental implant placement in fully edentulous maxilla.Interantral height (IBH) was measured using panoramic radiography and computed tomography (CT). Interantral width (IBW) by means CT.The difference between both imaging methods IBH assessment highly statistically significant (p < 0.001) canine area, whereas other areas it found not to be significant. Measured CT scans, is significantly higher area compared central lateral incisors...

10.7727/wimj.2013.059 article EN West Indian Medical Journal 2014-07-04

Aim: This article covers the authors' experience with treatment of bisphosphonate-related osteonecrosis jaw in 11 individuals. Methods: A retrospective study patients diagnosed and treated for at Department Dentistry, University Hospital Hradec Králové during period January 2006 to October 2012. The protocol consisted antimicrobial mouth rinses systemic antibiotic administration according stage disease. Additional surgical debridement sequestrectomy combination therapy was performed two...

10.5507/bp.2013.069 article EN cc-by Biomedical Papers 2013-09-30
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