- Bone fractures and treatments
- Orthopaedic implants and arthroplasty
- Bone Tissue Engineering Materials
- Hip and Femur Fractures
- Spine and Intervertebral Disc Pathology
- Reconstructive Surgery and Microvascular Techniques
- Osteoarthritis Treatment and Mechanisms
- Cancer-related molecular mechanisms research
- Orthopedic Infections and Treatments
- Orthopedic Surgery and Rehabilitation
- Bone Tumor Diagnosis and Treatments
- Circular RNAs in diseases
- Spinal Fractures and Fixation Techniques
- Total Knee Arthroplasty Outcomes
- Bone health and treatments
- Shoulder Injury and Treatment
- Titanium Alloys Microstructure and Properties
- Dental Implant Techniques and Outcomes
- Knee injuries and reconstruction techniques
- Bone and Joint Diseases
- Trauma Management and Diagnosis
- Tendon Structure and Treatment
- Surgical Sutures and Adhesives
- Nerve Injury and Rehabilitation
- Palliative Care and End-of-Life Issues
Wuxi People's Hospital
2010-2024
Nanjing Medical University
2015-2024
China Three Gorges University
2023-2024
People's Hospital of Yangzhong
2015
Abstract Because of stress shielding effects, traditional titanium (Ti) alloy scaffolds have a high elastic modulus, which might promote looseness and bone disintegration surrounding the implant, increasing likelihood second surgery. In contrast, 3D-printed porous Ti can reduce scaffold weight while enhancing biocompatibility. Further, these scaffolds’ nature allows tissue ingrowth as well strong pore connectivity, improve nutrient absorption. Nevertheless, bare implants may fail because...
The aim of this study was to perform an evaluation a braided fiber scaffold for anterior cruciate ligament (ACL) reconstruction. composed 50% type I collagen (Col-I) and polyvinyl alcohol (PVA). First, the biocompatibility in vitro weight loss were tested. Then, scaffolds used reconstruct ACL China Bama mimi pigs. At 24 weeks post-operation, mechanical properties histology regenerated analyzed. maximum load tensile strength 472.43± 15.2 N 29.71± 0.96 MPa, respectively; both ∼75% those native...
Abstract Background Chronic lumbar zygapophysial joint pain is a common cause of chronic low back pain. Percutaneous radiofrequency ablation (RFA) one the effective management options; however, results from traditional RFA need to be improved in certain cases. The aim this study investigate effect percutaneous under endoscopic guidance (ERFA) for secondary facet arthritis. Methods This prospective enrolled 60 patients. cases were randomized into two groups: 30 patients control group...
To investigate the role of microRNA-145 (miR-145) in steroid-induced necrosis femoral head (SINFH) by evaluating its effects on OPG/RANK/RANKL signaling pathway.A rat model SINFH was constructed via injection lentiviral vector pLV-shRNA-miR-145. Pathological observation performed tartrate-resistant acid phosphatase (TRAP) staining, and serum OPG levels were detected ELISA. The mRNA expression miR-145, OPG, RANK RANKL THP-1 cells assessed RT-PCR, protein western blotting.The miR-145...
Background. Patellar fractures account for approximately 1% of all fractures. Due to the patella’s importance as regards extensor mechanism, effort should be made preserve patella. Several operative treatment methods have been introduced patella fractures.Objectives. This study aims compare clinical effect a titanium cable tension band and nickeltitanium (NiTi) concentrator (NT-PC) in treating fractures.Material Methods. Thirty-nine patients with were enrolled this retrospective study. All...
The aims of this study were to discuss the principle, therapeutic effect and influencing factors multiple wrapped cancellous bone graft methods for treatment segmental defects.This retrospectively analyzed different autologous techniques on 51 patients aged (34.5 ± 11.5) years with defects. Cancellous bones titanium mesh (n = 9), line 10), suturing or binding cortical block, 13), induced membrane 19). defeats as follows: tibia 23), radial humerus 8), ulnar 7), femur 3). defect lengths (5.9...
A 40-year-old man presented with right crus pain for a month.Magnetic resonance imaging showed mixed signals in the mid-distal segment of tibia and distal part fibula, low high on T1-and T2-weighted images, respectively (Fig. 1).Tibial lesions penetrated cortex, puncture biopsy revealed ameloblastoma.Enneking stage was IB (G1, T2, M0).
Percutaneous kyphoplasty (PKP) is a procedure performed by spine surgeon who undergoes either orthopedic or neurosurgical training. The relationship between short-term adverse outcomes and specialty presently unknown. To compare of single-level PKP when neurosurgeons surgeons in order to develop more concretely preventive strategies for patients under consideration PKP.We evaluated underwent from 2012 2014 through the American College Surgeons National Surgical Quality Improvement Program...
We aimed to investigate the expression level of long noncoding RNA (lncRNA) zinc finger E-box-binding homeobox two antisense 1 (ZEB2-AS1) in osteosarcoma and explore its possible regulatory mechanisms. Expression lncRNA ZEB2-AS1 was detected by quantitative real-time PCR 63 cancerous tissues 25 adjacent normal mucosal from patients with osteosarcoma. The correlation between clinicopathological characteristics were evaluated, 5-year overall survival (5OS) also analyzed according expression....
AbstractMicro-arc oxidation (MAO) is commonly applied to modify the surface of titanium (Ti)-based medical implants with a bioactive and porous Ti oxide (TiO2) coating. The study reports new method incorporating hydroxyapatite (HA) within TiO2 coating by MAO alkali heat treatment (AHT) in solution containing Ca ion P ion. morphology, composition phase coatings were analyzed scanning electron microscopy energy-dispersive X-ray spectrometer diffraction. Surface topography roughness...
The aim of this study is to investigate the outcome these limb-threatening injuries through external fixation treatment and discuss case patients' functional recovery after fixation.Demographics, surgical outcomes in 88 patients with lower leg arterial treated by at two trauma centers from 2009 2018 were reviewed. primary was rate successful salvage, while secondary complications recovery.Eighty-eight identified 80 (90 legs) maintained a salvage. mean age 32.7 ± 10.8 years, 81.8% male....
MicroRNA (miRNA/miR)‑124‑3p has been extensively studied in tumor biology and stem cells. However, little is known regarding its functional roles the differentiation of precartilaginous cells (PSCs) into nucleus pulposus‑like (NPLCs). In present study, using miRNA microarray screening, it was demonstrated that expression profiles differed between rat primary PSCs TGF‑β1‑induced differentiated NPLCs, miR‑124‑3p significantly differentially expressed during to NPLCs. Furthermore, RT‑qPCR...
This study aimed to investigate the occurrence of dislocation and risk factors following primary total hip arthroplasty (THA). Retrospective analysis was done on clinical data 441patients with who were admitted our hospital between May 2018 early December 2020. A 294 patients without posterior soft tissue repair included as control group, a 147 short external rotator muscle joint capsule assigned group. All operated observed analyze postoperative dislocation. Within 6 months after...
Abstract Purpose The purpose of this study was to review the roles using external fixation rescue patients who sustained arterial injuries in lower legs. Methods Demographics, surgical treatment and outcomes 88 with leg treated by at two trauma centers from 2009 2018 were reviewed. primary outcome rate successful salvage, while secondary complications functional recovery. Results 80 (90 legs) maintained a salvage. followed up for an average 15.5±5.5 months. 6 (8 pins) experienced pin-tract...
Objective To observe the effect of Jianpi-Huoxue decoction on adrenocorticotropic hormone levels and vascular endothelial growth factor patients with chronic nephritis. Methods 120 nephritis from January 2012 to December 2013 in TCM Hospital Yanggu county were selected recruited into a control group treatment group, 40 each according random number table method. The was given oral indomethacin, 1 tablets time, 3 times/d; intramuscular injection methotrexate, piece/time, times/week....
Fibrous dysplasia (FD) is a common benign skeletal disease. In this report, we retrospectively analyzed two cases of monostotic FD with extensive lesions involving the middle and proximal humerus fractures, where thorough curettage autograft followed by interfixation were performed. However, one patient was cured successfully, other had repeated recurrences pathological fractures. Finally, help computer-aided design three-dimensional printing technology, unconstrained reverse shoulder...
Based on the previous research production plan and case study of sugarcane enterprises based quadratic programming modeling, optimization theory method modeling in operations were applied to conduct a more in-depth simulation calculation enterprises: On basis original planning model, parameter variables have been introduced improve calculations reflect various scenarios are realistic large-scale situation during peak harvest season. Decision makers can adjust line timely manner number...
Objective To observe the effect of hyperbaric oxygen (HBO) therapy on bone ingrowth into porous implant in a rabbit model avascular necrosis femoral head induced by dexamethasone. Methods Thirty-two New Zealand rabbits were subject to intramuscular injection dexamethasone twice week for 8 weeks.Then,rabbits divided 4 groups:control group,HBO group,recombinant human morphogenetie protein-2 (rhBMP-2) group and HBO + rhBMP-2 randomly.The femurs control implanted with bare implants,while...