- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Adrenal and Paraganglionic Tumors
- Gastric Cancer Management and Outcomes
- Hormonal Regulation and Hypertension
- Prostate Cancer Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Prostate Cancer Treatment and Research
- Appendicitis Diagnosis and Management
- Diverticular Disease and Complications
- Gallbladder and Bile Duct Disorders
- Anorectal Disease Treatments and Outcomes
- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
- Advanced Radiotherapy Techniques
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Hernia repair and management
- Biliary and Gastrointestinal Fistulas
- Breast Cancer Treatment Studies
- Abdominal Surgery and Complications
- COVID-19 and healthcare impacts
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal disorders and treatments
Marche Polytechnic University
2016-2025
St Vincent's Hospital
2018-2025
St. Vincent's Hospital
2025
Saint Vincent's Catholic Medical Center
2025
Ospedali Riuniti di Ancona
2002-2024
University of Padua
2021-2024
Istituto Nazionale di Riposo e Cura per Anziani
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2024
Azienda Ospedaliero Universitaria Ospedali Riuniti
2007-2024
Australian and New Zealand Intensive Care Society
2017-2023
Abstract Background In selected patients with early low rectal cancer, locoregional excision combined neoadjuvant therapy may be an alternative treatment option to total mesorectal (TME). Methods This prospective randomized trial compared endoluminal resection (ELRR) by transanal endoscopic microsurgery versus laparoscopic TME in the of small non-advanced cancer. Patients cancer staged clinically as cT2 N0 M0, histological grade G1–2, a tumour less than 3 cm diameter, within 6 anal verge,...
To evaluate the expression of renin-angiotensin system (RAS) genes in visceral (VAT) and subcutaneous adipose tissue (SAT) normotensive subjects with different body mass index (BMI). Adipose was obtained from 22 (12 normal weight 10 overweight) patients during surgery for colecystectomy. Angiotensinogen (AGT), angiotensin II receptor type 1 (AT1), converting enzyme (ACE) mRNA, protein levels were measured by reverse transcriptase-polymerase chain reaction Western blot analysis, respectively....
Local excision after radiotherapy for node-negative low rectal cancer may be an alternative to radical excision. This study evaluated the results of local in patients with small (less than 3 cm diameter) T2 and T3 distal tumours following neoadjuvant therapy.One hundred (54 uT2 46 uT3 uN0 tumours) were enrolled. All underwent preoperative followed by means transanal endoscopic microsurgery.Definitive histological examination revealed nine pT1, 54 pT2 19 pT3 tumours. A complete response (R0)...
BACKGROUND: Transanal local excision has been suggested as an attractive approach for patients with rectal cancer who show a major clinical response after preoperative chemoradiotherapy. OBJECTIVE: To evaluate the impact of transanal on recurrence in had DESIGN: Sequential 2-stage phase II study early efficacy. SETTING: Multicenter study. PATIENTS: Patients T3 or low-lying T2 adenocarcinoma that showed Eligible underwent full-thickness excision. According to their histopathology, staged...
Extending the interval between end of neoadjuvant chemoradiotherapy (CRT) and surgery may enhance tumor response in patients with locally advanced rectal cancer. However, data on association delaying long-term outcome who had a minor or poor are lacking.To assess large series no to CRT shorter longer waiting times short- outcomes.This is multicenter retrospective cohort study. Data from 1701 consecutive cancer treated 12 Italian referral centers were analyzed for colorectal January 2000...
Although rectal cancer is predominantly a disease of older patients, current guidelines do not incorporate optimal treatment recommendations for the elderly and address only partially associated specific challenges encountered in this population. This results wide variation disparity delivering standard care to subset patients. As burden population continues increase, it crucial assess whether on strategies general can be adopted adults, with same beneficial oncological functional outcomes....
The finding of increased left ventricular (LV) mass in hypertensive subjects with blunted nocturnal fall blood pressure (BP) might be an artifact matching patients for daytime BP, resulting higher 24-h BP nondippers. Therefore, we compared a large number (n = 1048) dippers and nondippers their LV at echocardiography before after adjustment 24-h, daytime, nighttime ambulatory BP. In men, the difference between was not significant but greater (more properly "peakers"). women, than both while...
To describe our experience in treating rectal cancer by transanal endoscopic microsurgery (TEM), report morbidity and mortality oncological outcome.A total of 425 patients with (120 T1, 185 T2, 120 T3 lesions) were staged digital examination, rectoscopy, endosonography, magnetic resonance imaging and/or computed tomography. Patients T1-N0 lesions favourable histological features underwent TEM immediately. preoperative stage T2-T3-N0 high-dose radiotherapy; from 1997 those aged less than 70...