A5041812715- Neurobiology of Language and Bilingualism
- Neuroendocrine regulation and behavior
- Phonetics and Phonology Research
- Action Observation and Synchronization
- Child and Adolescent Psychosocial and Emotional Development
- Multisensory perception and integration
- Maternal Mental Health During Pregnancy and Postpartum
- Neuroscience and Music Perception
- Infant Health and Development
- Psychosomatic Disorders and Their Treatments
- Reading and Literacy Development
- Neurotransmitter Receptor Influence on Behavior
- Dementia and Cognitive Impairment Research
- Categorization, perception, and language
- Syntax, Semantics, Linguistic Variation
- Neural and Behavioral Psychology Studies
- Heart Rate Variability and Autonomic Control
- Substance Abuse Treatment and Outcomes
- Speech Recognition and Synthesis
- Neural dynamics and brain function
- Speech and dialogue systems
- Linguistic Variation and Morphology
- Cannabis and Cannabinoid Research
- Alzheimer's disease research and treatments
- Language Development and Disorders
Leiden University
2013-2025
Leiden University Medical Center
2018-2020
Amsterdam UMC Location Vrije Universiteit Amsterdam
2017
Dutch Institute for Alcohol Policy
2016
The present study investigated the nature of physiological cue reactivity and craving in response to alcohol cues among alcohol-dependent patients (N = 80) who were enrolled detoxification treatment. Further, predictive value with regard future drinking both magnitude while treatment degree alcohol-cue exposure patients' natural environment was assessed. Physiological experimental soft drink advertisements measured during using heart rate variability subjective rating craving. Following...
In natural languages, two negating elements that cancel each other out (as in not impossible) are logically equivalent to the non-negated word form (in this case, possible). It has been proposed function of sentential double negation is create coherence between sentences containing opposing information. Thus, impossible functionally different from possible. The present ERP study tested hypothesis Dutch. Native speakers read which evoked negative expectations cancelled by a second sentence...
Previous studies have demonstrated that classifiers associated with nouns are activated during lexical access. Shape classifiers, a specific type, incorporate visual shape information. This study examined how information in is processed the production of classifier-noun phrases by native Chinese speakers. Participants performed picture-naming task using blocked cyclic naming paradigm, where classifier congruency and similarity were manipulated. Behavioural results revealed effect, slower...
Background Alexithymia, a condition characterized by deficits in interpreting and regulating feelings, is risk factor for variety of psychiatric conditions. Little known about how alexithymia influences the processing emotions music speech. Appreciation such emotional qualities auditory material fundamental to human experience has profound consequences functioning daily life. We investigated neural signature means event-related potentials. Methodology Affective speech prosody were presented...
The phenomenon of affective priming has caught scientific interest for over 30 years, yet the nature effect remains elusive. This study investigated underlying mechanism cross-modal and influence incongruence in music speech on negativities N400 time-window. In Experiment 1, participants judged valence targets (affective categorization). We found that were evaluated faster when preceded by affectively congruent visual word primes, vice versa. was accompanied a significantly larger N400-like...
How we perceive emotional signals from our environment depends on personality. Alexithymia, a personality trait characterized by difficulties in emotion regulation has been linked to aberrant brain activity for visual processing. Whether alexithymia also affects the brain's perception of speech prosody is currently unknown. We used functional magnetic resonance imaging investigate impact hemodynamic three priori regions network: superior temporal gyrus (STG), inferior frontal and amygdala....
Self-perceived word-finding difficulties are common in aging individuals as well Alzheimer's Disease (AD). Language and speech deficits difficult to objectify with neuropsychological assessments. We therefore aimed investigate whether amyloid, an early AD pathological hallmark, is associated speech-derived semantic complexity. included 63 subjective cognitive decline (age 64 ± 8, MMSE 29 1), amyloid status (positron emission tomography [PET] scans n = 59, or Aβ1-42 cerebrospinal fluid [CSF]...
Abstract Drugs of abuse stimulate striatal dopamine release and activate reward pathways. This study examined the impact alcohol cannabis marketing on circuit in users while sober intoxicated. It was predicted that would increase activation when sensitivity be less during intoxication. Heavy ( n = 20) regular 21) participated a mixed factorial involving administration placebo group group. Non‐drug served as between reference. Brain after exposure to movies measured using functional magnetic...
Perceiving potential threat to an infant and responding it is crucial for offspring survival parent–child bonding. Using a combination of functional magnetic resonance imaging multi-informant reports, this longitudinal study explores the neural basis paternal responses infants pre-natally (N = 21) early post-natally (n 17). Participants viewed videos showing in danger matched control videos, while instructed imagine that was their own or someone else’s. Effects were found infant-threatening...
The underlying mechanisms of paternal responses to infant signals are poorly understood. Vasopressin has previously been proposed affect these responses. Using a double-blind, placebo-controlled, within-subject design (N = 25 expectant fathers), we examined the effect vasopressin administration on use excessive handgrip force during exposure crying versus matched control sounds, while participants saw morphed images representing their own an unknown infant. We found that, compared placebo,...
According to Levelt’s language production model, name an object, speakers must first conceptualise and lexicalise the object before its can be articulated. Conceptualisation is conducted through semantic network that exists at conceptual level, with highly activated concept(s) activating lexical items lemma is, lexicalisation. So far, research focused mostly on categories (i.e., interference) but less so animacy—a concept correlated categories. To investigate role of this feature in...
In the last decades, parenting researchers increasingly focused on role of fathers in child development. However, it is still largely unknown which factors contribute to fathers' beliefs about their child, may be crucial transition fatherhood. current randomized within-subject experiment, effect nasal administration vasopressin (AVP) both Five Minute Speech Sample-based (FMSS) expressed emotion and emotional content or prosody was explored 25 prospectivefathers. Moreover, we how fatherhood...
Subjective cognitive decline (SCD) could be a potential harbinger of AD. People with SCD often experience word-finding problems, but these are difficult to objectify neuropsychological or linguistic assessments and it is unknown whether they related underlying Alzheimer pathology. We aim investigate semantic complexity, determined from spontaneous speech reduced in patients preclinical included 61 cognitively normal (age 64±8, 41% female, MMSE 29±1), available amyloid status, recordings...
Adult native Dutch speakers tend to have difficulty learning the English /æ/-/ɛ/ contrast because both vowels can be assimilated /ε/. Two experiments examined how this is acquired by adults and relationship between perception production in process. In Experiment 1, a four-day perceptual training protocol on /æ/-/ε/ was combined with related or unrelated practice (participants said target word phonologically after each decision). There improvement over four days production, but no effect of...