A5102025493- Autophagy in Disease and Therapy
- Catalytic Processes in Materials Science
- Sirtuins and Resveratrol in Medicine
- Catalysis and Oxidation Reactions
- Calcium signaling and nucleotide metabolism
- Zeolite Catalysis and Synthesis
- Neuroinflammation and Neurodegeneration Mechanisms
- Tuberculosis Research and Epidemiology
- Mesoporous Materials and Catalysis
- Catalysis and Hydrodesulfurization Studies
- Neurological Disease Mechanisms and Treatments
- Polyoxometalates: Synthesis and Applications
- Catalysts for Methane Reforming
- Catalysis for Biomass Conversion
- Carbon dioxide utilization in catalysis
- Lysosomal Storage Disorders Research
- Parkinson's Disease Mechanisms and Treatments
- Electrocatalysts for Energy Conversion
- Nanomaterials for catalytic reactions
- Fuel Cells and Related Materials
- Neonatal Respiratory Health Research
- Immune cells in cancer
- Aluminum Alloys Composites Properties
- Asymmetric Hydrogenation and Catalysis
- High Entropy Alloys Studies
South China Agricultural University
2025
Kunming University of Science and Technology
2015-2024
Beihang University
2024
Chongqing University of Technology
2024
Shanghai Jiao Tong University
2023-2024
Xi'an City Planning&Design Institute (China)
2022
Harbin Institute of Technology
2020
State Key Laboratory of Automotive Simulation and Control
2019
Jilin University
2019
Tissue Genesis (United States)
2018
Ischemic stroke often induces excessive neuronal autophagy, resulting in brain damage; meanwhile, inflammatory responses stimulated by ischemia exacerbate neural injury. However, interactions between autophagy and microglial inflammation following ischemic are poorly understood. CX3CL1/fractalkine, a membrane-bound chemokine expressed on neurons, can suppress binding to its receptor CX3CR1 microglia. In the present study, investigate whether could alter CX3CL1 expression neurons consequently...
Zeolite beta, especially heteroatomic zeolite has been widely used in the industries of fine chemicals and petroleum refining because its outstanding thermal stability, acid resistance, unique 3-D open-frame structure. In this paper, aluminum-free Mn-β was hydrothermally synthesized SiO2-MnO2-(TEA)2O-NaF-H2O system. The effect chemical composition precursor mixture to crystallization Al-free investigated. characterized by inductively coupled plasma (ICP), XRD, thermogravimetric/differential...
Two-dimensional titanium carbide (Ti3C2Tx) has accumulated tremendous interest due to its high electrical conductivity combined with hydrophilicity. However, Ti3C2Tx MXene is prone oxidative deterioration and a short storage period, further processing also extremely difficult. Herein, we report highly cohesive dough state of solid content 19.4 wt% without binder-like additives. The surface inside the retain an appropriate number water molecules, which endows it good flame retardancy,...
The positive significance of nature to human' self-reported well-being has been widely confirmed, but less attention paid the study cancer patients, as well role time on restorative effects. Therefore, using virtual reality (VR) and inclusion patients with esophageal gastrointestinal participants, this conducted indoor experiments explore patients' psychophysiological recovery through perception five different environmental types three interventions per week. There were 63 participants...
Background: One-third of the world's human population is latently infected with Mycobacterium tuberculosis (Mtb), and individuals latent infection have a 10% risk developing active (TB) disease in their lifetime. Rv2660c (encoding hypothetical protein) closely correlated dormancy Mtb. Studies found that was preferentially expressed during for adaptation to lack nutrition hypoxia; however, precise function unknown. Identification characterization crucial understand host–pathogen interactions...
Autophagic/lysosomal dysfunction was a critical pathogenesis of neuronal death after an ischemic stroke, but what drove the impairment autophagic flux remained elusive. Studies indicated that histone H4 lysine 16 acetylation (H4K16ac) drastically modulated autophagic/lysosomal signaling pathway. Herein, we investigated whether in neurons could be restored by altering H4K16ac levels cerebral ischemia. The rat model stroke and cell ischemia HT22 were prepared middle artery occlusion (MCAO)...
Abstract A novel and effective catalytic system, silica-supported chitosan Schiff base palladium complex (SiO2–CS–Schiff base–Pd) was described for hydrogenation of aromatic ketones to corresponding hydrocarbons at ambient temperature normal pressure H2.
Autophagic/lysosomal dysfunction is a critical pathogenesis of neuronal injury after ischemic stroke. Trehalose has been validated to restore the impaired autophagy flux by boosting transcription factor EB (TFEB) nuclear translocation, but orally administrated trehalose can be greatly digested intestinal trehalase before entering into brain. Melibiose (MEL), an analogue trehalose, may thoroughly exert its pharmacological effects through oral administration due absence melibiase. The present...
Objective: Autophagy and apoptosis coexist in stroke, but the relationship between effects complex is poorly understood. Herein, we investigated dynamic changes of autophagy at penumbra permanent cerebral ischaemia. Methods: Sprague-Dawley rat models were prepared by middle artery occlusion. The evaluated Western blotting immunofluorescence with LC3-II cleaved caspase-3, respectively. neurological deficit score infarct volume assessed. Results: results showed that expressions caspase-3...
Neuronal death was frequently driven by autophagic/lysosomal dysfunction after ischemic stroke, whereas how to restore the impaired autophagic flux remained elusive. Autophagic/lysosomal signaling could be augmented transcription factor EB (TFEB) nuclear translocation, which facilitated its dephosphorylation. A key TFEB dephosphorylase calcineurin (CaN), whose activity drastically regulated cytosolic calcium ion concentration ([Ca2+]) controlled lysosomal Ca2+ channel-like protein of TRPML1....
The present work investigates the microstructure and tensile properties of a hot rolled 6061 alloy quenched by cold rolls (RQ) at different preheating temperatures. temperature strongly affects evolution mechanical properties. Low (490 °C) resulted in both low strength elongation. RQ preheated 540 °C exhibited improved ductility compared to those subjected T6 T8 temper, comparable that after temper. dynamic recovery during rolling contributed elongation retained hardening. High also led...