A5085844617- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Heavy Metal Exposure and Toxicity
- Air Quality and Health Impacts
- Blood Coagulation and Thrombosis Mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Pain Mechanisms and Treatments
- Anesthesia and Neurotoxicity Research
- Spine and Intervertebral Disc Pathology
- Orthopedic Infections and Treatments
- Music Therapy and Health
- Musculoskeletal Disorders and Rehabilitation
- Antiplatelet Therapy and Cardiovascular Diseases
- Heme Oxygenase-1 and Carbon Monoxide
- Anesthesia and Pain Management
- Protease and Inhibitor Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Radiation Dose and Imaging
- Traditional Chinese Medicine Analysis
- Climate Change and Health Impacts
- Noise Effects and Management
- Biological and pharmacological studies of plants
- Acute Ischemic Stroke Management
- Peripheral Artery Disease Management
- Urinary Bladder and Prostate Research
Korea University
2019-2024
Ansan University
2019-2024
Weatherford College
2022
The objective of this study was to evaluate the effects high levels maternal exposure ambient air pollution and heavy metals on risks autism spectrum disorder (ASD) epilepsy using National Health Insurance claims data South Korea. mothers their newborns from 2016 2018 provided by Service were used (n = 843,134). Data pollutants (PM2.5, CO, SO2, NO2, O3) (Pb, Cd, Cr, Cu, Mn, Fe, Ni, As) during pregnancy matched based mother's registration area. SO2 (OR: 2.723, 95% CI: 1.971-3.761) Pb 1.063,...
According to a recent meta-analysis, in patients with body mass index (BMI) ≥ 30, high fraction of inhaled oxygen (FiO2) did not increase postoperative atelectasis. However, FiO2 generally increases the risk Therefore, this study aimed evaluate effect on development atelectasis obese using modified lung ultrasound score (LUSS).Patients were assigned 4 groups: BMI 30: group A (n = 21) and B 20) normal BMI: C 22) D 21). Groups administered 100% O2 during preinduction emergence 50% anesthesia....
An ischemic cerebral stroke results from the interruption of blood flow to brain, triggering rapid and complex cascades excitotoxicity, oxidative stress, inflammation. Current reperfusion therapies, including intravenous thrombolysis mechanical thrombectomy, cause further brain injury due reperfusion-induced cytotoxicity. To date, novel cytoprotective therapies that could address these challenges have yet be developed, likely limitations targeting a single pathologic mechanism. unmet...
Patients with peripheral arterial disease (PAD) are at a higher risk of developing postoperative complications. Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) plays an important role in atherosclerosis pathogenesis. In this study, the relationship between PAD and several single nucleotide polymorphisms (SNPs) ALOX5AP (rs17216473, rs10507391, rs4769874, rs9551963, rs17222814, rs7222842) was investigated elderly patients undergoing general surgery. The medical records 129 aged >...
Postoperative residual pain and dysesthesia in patients with lumbar spinal stenosis (LSS) can reduce patient satisfaction. We investigated the effects of nefopam on dysesthesia, postoperative pain, satisfaction LSS who underwent spine surgery. A total 73 were randomly assigned to two groups: group (n = 35), receiving a 20 mL normal saline-based solution containing mg, control 38), which received saline 1 h before end operation. incisional scores, overall management evaluated. The severity...
Acute ischemic stroke is the leading cause of morbidity and mortality worldwide. Recombinant tissue plasminogen activator (rtPA) only agent clinically approved by FDA for patients with acute stroke. However, delayed treatment rtPA (e.g., more than 3 h after onset) exacerbates brain damage causing intracerebral hemorrhage increasing neurotoxicity. In present study, we investigated whether neuroprotant otaplimastat reduced treatment-evoked neurotoxicity in male Sprague Dawley rats subjected to...
Catheter-related bladder discomfort (CRBD) is one of the most difficult symptoms during postoperative period. Nefopam a non-narcotic analgesic agent, which also has anticholinergic action. This study was performed to evaluate effects nefopam on CRBD in male patients undergoing robotic nephrectomy. A total 109 were randomly divided into two groups: control group (n = 55) received 20 mL normal saline, and 54) mg 1 h before end operation. At times min, h, 2 6 severity measured using an 11-point...
The preoperative elevation of ammonia may be associated with postoperative neurologic complications. aim this study was to evaluate the effect level on incidence delirium in patients after liver transplantation (LT). Patients (n = 260) who received LT from January 2010 July 2017 a single university hospital were retrospectively reviewed. patients' demographic data, perioperative managements, and complications assessed. divided into following 2 groups: those had (Group A, n 158) normal range...
Air pollution and heavy metal exposure are emerging public health concerns. Prenatal to air pollutants metals has been implicated in the development of congenital heart disease (CHD). However, relationship between airborne CHD not yet investigated. Therefore, this large population-based study, we investigated association pollutants, including metals, risk using national insurance claims data from South Korea. Data regarding 1,129,442 newborns their mothers were matched with pollutant levels...
Background: Although midazolam is widely administered as an anxiolytic premedication, it may cause over-sedation and hypoxia in geriatric patients. Cranial electrotherapy stimulation (CES) a nonpharmacological device with effect. This study compared the effects of CES preoperative treatment Methods: Eighty patients, under age 65 to 79 years, undergoing general anesthesia were randomly assigned into premedication group (M group, n = 40) or pretreatment (CES 40). The patients M intramuscularly...
Background: We previously found an association between preoperative bilirubin concentration and cognitive impairment after liver transplantation. In order to study a possible mechanism for causing postoperative dysfunction, we investigated the effect of high concentrations on blood–brain barrier. Methods: Our model system was 30-week-old transgenic zebrafish fabp10a:cfp-NTR. preliminary experiments confirmed systemic absorption retro-orbital injection using reddish Rhodamine-dextran injected...
There are various reports on the effect of anesthetic method neurologic complication.Especially, there is controversy about general anesthesia and regional incidence postoperative delirium after total hip replacement arthroplasty (THRA). A population-based study was conducted to estimate in patients with THRA South Korea.