Leonidas Tapias

ORCID: 0000-0003-4014-0924
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About
Contact & Profiles
Research Areas
  • Pleural and Pulmonary Diseases
  • Tracheal and airway disorders
  • Congenital Diaphragmatic Hernia Studies
  • Myasthenia Gravis and Thymoma
  • Esophageal and GI Pathology
  • Infectious Diseases and Tuberculosis
  • Lung Cancer Diagnosis and Treatment
  • Trauma Management and Diagnosis
  • Gastric Cancer Management and Outcomes
  • Cardiac Fibrosis and Remodeling
  • Esophageal Cancer Research and Treatment
  • Diagnosis and treatment of tuberculosis
  • Thyroid and Parathyroid Surgery
  • Cardiac Ischemia and Reperfusion
  • Lung Cancer Research Studies
  • Angiogenesis and VEGF in Cancer
  • Lung Cancer Treatments and Mutations
  • Medical Imaging and Pathology Studies
  • Cardiovascular Function and Risk Factors
  • Dysphagia Assessment and Management
  • Vascular Anomalies and Treatments
  • Pituitary Gland Disorders and Treatments
  • Case Reports on Hematomas
  • Hernia repair and management
  • Apelin-related biomedical research

University Hospitals of Cleveland
2023-2024

Case Western Reserve University
2023-2024

UConn Health
2014-2023

University School
2023

Baylor University Medical Center
2021

Baylor Scott & White Health
2020

Foscal Hospital
2009-2020

Massachusetts General Hospital
2017-2019

University of Saint Mary
2015-2018

University of Connecticut
2018

Background The present study demonstrates that the ubiquitin E3 ligase, Pellino-1 (Peli1), is an important angiogenic molecule under control of vascular endothelial growth factor (VEGF) receptor 2/Flk-1. We have previously reported increased survivability ischemic skin flap tissue by adenovirus carrying Peli1 (Ad-Peli1) gene therapy in Flk-1+/- mice. Methods and Results Two separate experimental groups mice were subjected to myocardial infarction ( MI ) followed immediate intramyocardial...

10.1161/jaha.117.007601 article EN cc-by-nc-nd Journal of the American Heart Association 2018-09-16

Adequate nutrition is challenging after oesophagectomy. A jejunostomy commonly placed during oesophagectomy for nutritional support. However, some patients develop jejunostomy-related complications and the benefit over oral alone unclear. This study aims to assess impact of intraoperative placement on weight loss perioperative outcomes in with oesophageal cancer treated minimally invasive Ivor Lewis (MIE).From a prospectively maintained database, were identified who underwent MIE gastric...

10.1093/ejcts/ezz063 article EN European Journal of Cardio-Thoracic Surgery 2019-02-18

Vaping, the use of electronic cigarettes, involves different mechanics than conventional combustion cigarettes. Consumers who vape tend to overinhale and then forcefully exhale eliminate vapor, which is usually produced in much greater quantity generated by a regular cigarette. Effectively, they are performing an exaggerated Valsalva maneuver. This can increase their risk for developing potential spontaneous pneumomediastinum. Here we present case pneumomediastinum secondary cigarette use.

10.1080/08998280.2020.1717407 article EN Baylor University Medical Center Proceedings 2020-02-06

In May 2004, a 48‐year‐old male surgeon, resident in Bucaramanga, Colombia, suffered superficial cut with scalpel to the lateral aspect of mid‐phalanx second finger left hand while performing pulmonary decortication surgical procedure for tuberculous empyema entrapment. The injury healed normally but, approximately 2 weeks after event, an erythematous, nonpainful papule 3 mm diameter developed, and increased progressively 7 days its initial appearance. At this time, showed spontaneous...

10.1111/j.1365-4632.2008.03656.x article EN International Journal of Dermatology 2008-07-17

Drainage of the thoracic cavity is a frequent clinical procedure performed for diagnostic and therapeutic purposes. Most common indications are related with conditions where air, blood, lymph, pleural fluid, pus, other materials accumulate in chest cavity. It important to know technique tube thoracostomy be familiar more associated complications. We have literature review emphasis on complications insertion intrathoracic tubes. papers encountered retrospective studies context trauma. General...

10.30944/20117582.680 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2020-05-01

Abdominal aortic aneurysm repair by endovascular techniques have gained wide acceptance as a treatment option. A potential well-known complication of includes endoleak. Specifically, type II endoleak, which is described retrograde flow into the sac through collateral vessels, can occur in up to 30% patients. Certain preoperative factors predict patients may develop This article describes laparoscopic inferior mesenteric artery ligation prior abdominal viable option prevention

10.1177/1553350611432720 article EN Surgical Innovation 2012-02-14

Background Current practice patterns suggest open rather than minimally invasive (MIS) approaches for thymomas >4 cm. We hypothesized there would be similar perioperative outcomes and overall survival between MIS large (>4 cm) thymoma resection. Methods The National Cancer Database was queried patients who underwent thymectomy from 2010 to 2020. Surgical approach characterized as either or MIS. primary outcome secondary were margin status, length of stay (LOS). Differences cohorts...

10.1177/00031348241246180 article EN The American Surgeon 2024-04-08

Staghorn calculi pose challenges in urology, often necessitating more invasive procedures such as percutaneous nephrolithotomy (PCNL) to clear a large stone burden with fewer procedures. Here we present case of 76‐year‐old female chronic kidney disease and malrotated right pelvic who underwent PCNL for 3.5 cm staghorn calculus. Postoperatively, she developed rare complication ascending colon perforation, requiring emergent surgical intervention including exploratory laparotomy hemicolectomy....

10.1155/2024/4475216 article EN cc-by Case Reports in Surgery 2024-01-01

Historically, pulmonary resections for lung cancer have been done in an open fashion. With the adoption of VATS, incisions became smaller but challenges such as cost, safety, and quality resection center discussion. However, now we extensive evidence benefit minimally invasive approaches. introduction robotic-assisted thoracic surgery (RATS), discussion has gone back to cost main driver. This increased robotic evaluated by multiple studies without a general consensus, given varying...

10.21037/vats.2019.12.02 article EN Video-Assisted Thoracic Surgery 2020-02-25
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