A5062021711- Cardiac, Anesthesia and Surgical Outcomes
- Patient Safety and Medication Errors
- Transplantation: Methods and Outcomes
- Cardiac Ischemia and Reperfusion
- Cardiac Valve Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Cardiac Structural Anomalies and Repair
- Cancer, Hypoxia, and Metabolism
- Cardiac Arrest and Resuscitation
- Cardiovascular Function and Risk Factors
- Liver Disease and Transplantation
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Liver Disease Diagnosis and Treatment
- Angiogenesis and VEGF in Cancer
- Healthcare cost, quality, practices
- Xenotransplantation and immune response
- Medical Malpractice and Liability Issues
- Nutrition and Health in Aging
- Finance, Taxation, and Governance
- Gastrointestinal disorders and treatments
- Conducting polymers and applications
- Congenital Heart Disease Studies
- Administrative Law and Governance
- Air Quality and Health Impacts
Instituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias
2024
GE Vernova (United States)
2024
Hospital Del Mar
2006-2023
Chan Zuckerberg Initiative (United States)
2023
HCA Healthcare
2023
University of San Carlos of Guatemala
2023
Universidad Nacional de Colombia
2023
Columbia University
1990-2020
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2020
Universitat de Barcelona
2020
Little is known about the pathophysiology of myxomatous degeneration mitral valve, pathological hallmark valve prolapse, associated with symptomatic regurgitation, heart failure, and death. Excess transforming growth factor (TGF)-β signaling to cause regurgitation in a mouse model Marfan syndrome. We examined if TGF-β dysregulated clinical specimens sporadic prolapse compared explanted nondiseased valves we tested effects angiotensin II receptor blockers on cultured human cells.Operative...
The aim of this study is to describe the surgical technique, indications, advantages, and possible complications buccal fat pad flap report our clinical experience with for intraoral reconstruction after tumor removal.The has been used reconstruct oral defects resection in 32 patients, who have retrospectively analyzed.Adequate closure defect was achieved during surgery all cases. In one case, there partial loss flap; treated conservatively. five cases some retraction reconstructed...
Hypoxia-inducible transcription factor (HIF)-prolyl hydroxylases domain (PHD-1-3) are oxygen sensors that regulate the stability of HIFs in an oxygen-dependent manner. Suppression PHD enzymes leads to stabilization and offers a potential treatment option for many ischemic disorders, such as peripheral artery occlusive disease, myocardial infarction, stroke. Here, we show homozygous disruption PHD-1 (PHD-1(-/-)) could facilitate HIF-1α-mediated cardioprotection ischemia/reperfused (I/R)...
Objective— Neuropilin-1 (NRP-1) is a multidomain membrane receptor involved in angiogenesis and development of neuronal circuits, however, the role NRP-1 cardiovascular pathophysiology remains elusive. Approach Results— In this study, we first observed that deletion induced peroxisome proliferator–activated γ coactivator 1α cardiomyocytes vascular smooth muscle cells, which was accompanied by dysregulated cardiac mitochondrial accumulation induction hypertrophy- stress-related markers. To...
Oxymorphone was administered epidurally (0.1 mg/kg) or intramuscularly (IM) (0.2 to 16 dogs undergoing thoracotomy, compare the analgesic effectiveness. Heart rate, respiratory systolic and diastolic blood pressure, pain score were measured hourly. Arterial gases at hour 1. A single dose of oxymorphone injected provided analgesia for up 10 hours, whereas IM route a comparable effect less than 2 hours. There statistically significant increases in heart pressures treated over epidurally. We...