Hartmut Derendorf

ORCID: 0000-0003-4016-1370
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About
Contact & Profiles
Research Areas
  • Antibiotics Pharmacokinetics and Efficacy
  • Analytical Methods in Pharmaceuticals
  • Antibiotic Resistance in Bacteria
  • Pharmacogenetics and Drug Metabolism
  • Drug Transport and Resistance Mechanisms
  • Pharmaceutical studies and practices
  • Inhalation and Respiratory Drug Delivery
  • Asthma and respiratory diseases
  • Pneumonia and Respiratory Infections
  • Plant-based Medicinal Research
  • Bacterial Identification and Susceptibility Testing
  • Pharmacological Effects and Toxicity Studies
  • Analytical Chemistry and Chromatography
  • Adrenal Hormones and Disorders
  • Drug Solubulity and Delivery Systems
  • Antimicrobial Resistance in Staphylococcus
  • Hormonal and reproductive studies
  • Pharmacology and Obesity Treatment
  • Biosimilars and Bioanalytical Methods
  • Pesticide Residue Analysis and Safety
  • Inflammatory mediators and NSAID effects
  • Protein Interaction Studies and Fluorescence Analysis
  • Anesthesia and Sedative Agents
  • Pharmacological Effects of Natural Compounds
  • Spaceflight effects on biology

University of Florida
2013-2022

Florida College
2010-2020

Columbus Oncology and Hematology Associates
2014-2020

Reckitt Benckiser (United States)
2016-2017

National Institutes of Health Clinical Center
2017

Indiana University Bloomington
2017

Princeton University
2016

Eli Lilly (United States)
2016

Case Western Reserve University
2013

Tufts University
2013

Due to its potentially beneficial impact on human health, the polyphenol quercetin has come into focus of medicinal interest. However, data bioavailability after oral intake are scarce and contradictory. Previous investigations indicate that disposition may depend sugar moiety glycoside or plant matrix. To determine influence matrix absorption quercetin, two isolated glycosides extracts were administered 12 healthy volunteers in a four‐way crossover study. Each subject received an onion...

10.1177/00912700122010366 article EN The Journal of Clinical Pharmacology 2001-05-01

The intake of polyphenols has been demonstrated to have health-promoting and disease-preventive effects. pomegranate (Punica granatum L.), which is rich in several polyphenols, used for centuries ancient cultures its medicinal purposes. potential health benefits numerous vitro studies vivo experiments. This study investigated the absorption antioxidant effects a standardized extract from healthy human volunteers after acute consumption 800 mg extract. Results indicate that ellagic acid (EA)...

10.1021/jf061674h article EN Journal of Agricultural and Food Chemistry 2006-10-13

Triamcinolone acetonide, triamcinolone hexacetonide, and a combination of betamethasone phosphate acetate were given intra-articularly in different doses. Plasma levels the steroids measured pharmacokinetic parameters calculated. As pharmacodynamic parameter for systemic steroid activity, plasma hydrocortisone monitored 3 weeks. Results indicate complete absorption from site injection over period 2 to Because its lower solubility, hexacetonide is absorbed slower than thus maintaining...

10.1038/clpt.1986.45 article EN Clinical Pharmacology & Therapeutics 1986-03-01

The açai berry is the fruit of acai palm and traditionally consumed in Brazil but has gained popularity abroad as a food functional ingredient, yet little information exists on its health effect humans. This study was performed an acute four-way crossover clinical trial with pulp clarified juice compared to applesauce non-antioxidant beverage controls. Healthy volunteers (12) were dosed at 7 mL/kg body weight after washout phase overnight fast, plasma repeatedly sampled over 12 h urine 24...

10.1021/jf8007037 article EN Journal of Agricultural and Food Chemistry 2008-08-12
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