- Nanoplatforms for cancer theranostics
- Luminescence and Fluorescent Materials
- Pomegranate: compositions and health benefits
- Paraoxonase enzyme and polymorphisms
- Analytical Chemistry and Sensors
- Nanoparticle-Based Drug Delivery
- Polydiacetylene-based materials and applications
- Bone Tissue Engineering Materials
- Advanced Fluorescence Microscopy Techniques
- Carbon and Quantum Dots Applications
- Advanced Chemical Sensor Technologies
- Photochromic and Fluorescence Chemistry
- Quantum Dots Synthesis And Properties
- Genomics, phytochemicals, and oxidative stress
- Gas Sensing Nanomaterials and Sensors
- RNA Interference and Gene Delivery
- Photochemistry and Electron Transfer Studies
- Photodynamic Therapy Research Studies
- Ocular Infections and Treatments
- Advanced Sensor and Energy Harvesting Materials
- Biosensors and Analytical Detection
- Hops Chemistry and Applications
Pennsylvania State University
2018-2024
Westlake University
2024
Abstract The aryl hydrocarbon receptor (AHR) mediates intestinal barrier homeostasis. Many AHR ligands are also CYP1A1/1B1 substrates, which can result in rapid clearance within the tract, limiting systemic exposure and subsequent activation. This led us to hypothesis that there dietary substrates of functionally increase half‐life potent ligands. We examined potential urolithin A (UroA), a gut bacterial metabolite ellagitannins, as substrate enhance activity vivo. UroA is competitive for an...
Bases can promote keto-enol tautomerism, a prevalent form of prototropic and facilitate the ring opening anhydride structures. The intrinsic chemical distinctions between these processes provide an opportunity to modulate seemingly parallel reactions. However, this potential remains largely unexplored. In work, we report homophthalic anhydride, first molecule exhibiting simultaneous halochromism, turn-on fluorescence (halofluorochromism), subsequent self-destruction. Through comprehensive...
Halides play important roles in human health and environmental monitoring. However, different halides interfere with each other current measurement methods. Simultaneous sensing of multiple a fast low-cost manner remains challenge. Here, we report fluorometric multi-halide method by using single citrate-based fluorophore, CA-Cys, on custom-made portable device. The fluorescence emitted CA-Cys is quenched due to the dynamic quenching halide ions; sensitivities vary from types pH, providing...
Humidity sensors are important components in healthcare monitoring and advanced tactile sensing systems. However, low sensitivity poor mechanical properties limit their practical applications integrated haptic platforms such as artificial skin. Here, photoluminescence (PL)-type humidity materials with simultaneously high sensitivity, stretchability, healability reported based on poly(vinyl alcohol) (PVA) composite gels comprising CdxSe1–xZnyS1–y quantum dots (QDs). A droplet-assisted...
The aryl hydrocarbon receptor (AHR) mediates intestinal barrier homeostasis. Many AHR ligands are also CYP1A1/1B1 substrates, which can result in the rapid clearance within tract, limiting activation. This led us to hypothesis that there dietary substrates of increase half-life potent ligands. We examined potential urolithin A (UroA) as a substrate enhance activity vivo. UroA is competitive for an vitro competition assay. broccoli-containing diet promotes gastric formation hydrophobic ligand...
Abstract Biodegradable tissue engineering scaffolds have garnered increasing interest for their role in providing mechanical support, promoting regeneration, and eliminating the need removal. However, vivo degradation processes remain challenging to track. Here, a novel biodegradable polymer, N‐methyldiethanolamine (MDEA) Gadolinium(III) diethylenetriamine pentaacetate (Gd‐DTPA) modified photoluminescent polymers (BPLPMGd), which combines near‐infrared (NIR) fluorescence magnetic resonance...
The fluorescence emission spectrum of band-shifting imaging probes can shift under different excitation wavelengths. This unique property may be leveraged to enable chromatic encoding in two-photon imaging. Characterization the band shifting spectral and preliminary studies will presented.