A5085056433- Pregnancy-related medical research
- Preterm Birth and Chorioamnionitis
- Connective tissue disorders research
- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Endometriosis Research and Treatment
- Proteoglycans and glycosaminoglycans research
- Pelvic floor disorders treatments
- Neonatal Respiratory Health Research
- Wireless Body Area Networks
- Ovarian function and disorders
- Renal and related cancers
- Cell Adhesion Molecules Research
- Wnt/β-catenin signaling in development and cancer
- Congenital Diaphragmatic Hernia Studies
- Bluetooth and Wireless Communication Technologies
- Maternal and Perinatal Health Interventions
- Elasticity and Material Modeling
- Fibroblast Growth Factor Research
- Hypothalamic control of reproductive hormones
- Organ and Tissue Transplantation Research
- Embedded Systems Design Techniques
- Tissue Engineering and Regenerative Medicine
- Gestational Diabetes Research and Management
- Ectopic Pregnancy Diagnosis and Management
Sri Eshwar College of Engineering
2023
The University of Texas Southwestern Medical Center
2017-2022
University of Vermont
2021-2022
University of Illinois Urbana-Champaign
2012-2019
Summary Recently, much of the wireless personal area network (WPAN) research concerns protocols, scheduling, and security challenges but major issue resource utilization has been very rarely investigated. The design sharing in a gets more attention when number users increases. While optimizing performance, plays critical role. In this paper, numerical performance algorithm for bi‐partite scatternet is presented. This focused to enhance bandwidth allocation power scatternets. Every node can...
Summary In general, there are several many devices that can overload the network and reduce performance. Devices minimize interference optimize bandwidth usage by using directional antennas avoiding overlapping communication ranges. addition, need to carefully manage their use of resources, such as energy. Bandwidth is limited in wireless personal area networks (WPANs), so select which data send receive. this paper, an intelligent performance analysis energy‐efficient resource optimization...
The mammalian Msx homeobox genes, Msx1 and Msx2, encode transcription factors that control organogenesis tissue interactions during embryonic development. We observed overlapping expression of these in uterine epithelial stromal compartments pregnant mice prior to embryo implantation. Conditional ablation both Msx2 the uterus resulted female infertility due a failure In mutant (Msx1/2d/d), epithelium exhibited persistent proliferative activity failed attach embryos. Gene profiling stroma...
The extracellular matrix (ECM) plays an active and dynamic role that both reflects facilitates the functional requirements of a tissue. mature ECM nonpregnant cervix is drastically reorganized during pregnancy to drive changes in tissue mechanics ensure safe birth. In this study, our research on mice deficient proteoglycan decorin have led finding progesterone estrogen play distinct complementary roles orchestrate structural reorganization collagen elastic fibers pregnancy. Abnormalities...
With half a million babies born preterm each year in the USA and about 15 worldwide, birth (PTB) remains global health issue. Preterm is primary cause of infant morbidity mortality can impact lives long past infancy. The fact that there are numerous, many currently unidentified, etiologies PTB has hindered development tools for risk evaluation preventative therapies. Infection estimated to be involved nearly 40% PTBs known etiology; therefore, understanding how infection-mediated...
Abstract During gestation, the female reproductive tract must maintain pregnancy while concurrently preparing for parturition. Here, we explore transitions in gene expression and protein turnover (fractional synthesis rates [FSR]) by which cervix implements a transition from rigid to compliant. Shifts transcription achieve immune tolerance alter epithelial cell programs begin early pregnancy. Subsequently, mid-to-late transcriptional emerge that promote structural reorganization of...
Abstract The myometrium undergoes progressive tissue remodeling from early to late pregnancy support fetal growth and transitions the contractile phase deliver a baby at term. Much of our effort has been focused on understanding functional role myometrial smooth muscle cells, but extracellular matrix is not clear. This study was aimed demonstrate expression profile sub-sets genes involved in synthesis, processing, assembly collagen elastic fibers, their structural during pregnancy, hormonal...
Previous work has identified divergent mechanisms by which cervical remodeling is achieved in preterm birth (PTB) induced hormone withdrawal (mifepristone) or lipopolysaccharide (LPS). Our current study aims to document how collagen architecture modified achieve premature mice treated with LPS as a model of infection-induced inflammation. Cervices were collected on gestation day (d) 15 from ripening and compared d15 d18 controls well PTB model. Second harmonic generation (SHG) electron...
Endometrial stromal cells differentiate to form decidual in a process known as decidualization, which is critical for embryo implantation and successful establishment of pregnancy. We previously reported that bone morphogenetic protein 2 (BMP2) mediates uterine cell differentiation mice humans. To identify the downstream target(s) BMP2 signaling during we performed gene-expression profiling mouse cells, treated or not with recombinant BMP2. Our studies revealed expression Msx2, member...
Cervical remodeling is critical for a healthy pregnancy. The proper regulation of extracellular matrix (ECM) turnover leads to throughout gestation, transforming the tissue from stiff material compliant, extensible, viscoelastic prepared delivery. Small leucine-rich proteoglycans (SLRPs) regulate structural fiber assembly in cervical ECM and overall properties. To quantify SLRPs' mechanical role cervix, whole cervix specimens nonpregnant late pregnant knockout mice SLRPs, decorin biglycan,...
Arithmetic Logic Unit is the brain of all processors, composed an Adder circuit. The main component multiplier circuits adder, which performs subtraction (by 2’s complement arithmetic). Since most fundamental operation in mathematics addition, and adder essential part processor, study VLSI arithmetic has required many digital researchers. When designing systems employing approach, plays a major role. Low power based designs perform poorly because propagation delay issue. With aid PPA design,...