A5025702790- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Smoking Behavior and Cessation
- Cardiovascular Issues in Pregnancy
- Neonatal Respiratory Health Research
- Maternal and fetal healthcare
- Air Quality and Health Impacts
- Blood Coagulation and Thrombosis Mechanisms
- Cardiovascular Health and Disease Prevention
- Prenatal Screening and Diagnostics
- Health disparities and outcomes
- Ovarian function and disorders
- Reproductive System and Pregnancy
- Pregnancy-related medical research
- Endometriosis Research and Treatment
- Neonatal and fetal brain pathology
- Blood groups and transfusion
- Obesity, Physical Activity, Diet
- Ectopic Pregnancy Diagnosis and Management
- Maternal Mental Health During Pregnancy and Postpartum
- Breastfeeding Practices and Influences
- Neuroscience of respiration and sleep
- Temporomandibular Joint Disorders
- Fetal and Pediatric Neurological Disorders
University of Vermont Medical Center
2012-2025
University of Vermont
2014-2024
Michigan State University
2024
University of Toronto
1998-2021
Humber River Regional Hospital
2020
Women’s Health Care
2005-2017
Vermont Oxford Network
2015
Washington University in St. Louis
2011
Cambridge University Press
2008
Beijing Obstetrics and Gynecology Hospital
2005
Report of the American College Obstetricians and Gynecologists' Task Force on Hypertension in Pregnancy was developed by Pregnancy: James M. Roberts, MD, Chair; Phyllis A. August, MPH; George Bakris, MD; John R. Barton, Ira Bernstein, Maurice Druzin, Robert Gaiser, Joey R Granger, PhD; Arun Jeyabalan, MS; Donna D. Johnson, S. Ananth Karumanchi, Marshall Lindheimer, Michelle Y. Owens, Saade, Baha Sibai, Catherine Spong, Eleni Tsigas; staff: Gerald F. Joseph, Nancy O'Reilly, MHS; Alyssa...
Preeclampsia is a pregnancy-specific disorder of unknown etiology and leading contributor to maternal perinatal morbidity mortality worldwide. Because there no cure other than delivery, preeclampsia the cause iatrogenic preterm birth. We show that shares pathophysiologic features with recognized protein misfolding disorders. These include urine congophilia (affinity for amyloidophilic dye Congo red), affinity conformational state-dependent antibodies, dysregulation prototype proteolytic...
Maternal smoking has been associated with a reduction in newborn birth weight. We sought to estimate how the pattern of maternal throughout pregnancy influences size.One hundred sixty pregnant women were enrolled prospective study. collected data on age, education, prepregnancy body mass index, and parity, as well alcohol illicit drug use. Cigarette use was defined self-reported consumption before pregnancy, at time study enrollment, third trimester. Statistical analyses performed based...
This study examined whether voucher-based reinforcement therapy (VBRT) contingent upon smoking abstinence during pregnancy is an effective method for decreasing maternal and improving fetal growth.A two-condition, parallel-groups, randomized controlled trial was conducted in a university-based research clinic. A total of 82 smokers entering prenatal care participated the trial.Participants were assigned randomly to either or non-contingent voucher conditions. Vouchers exchangeable retail...
Recent studies have suggested that both embryonic stem cells and adult bone marrow can participate in the regeneration repair of diseased organs, including lungs. However, extent airway epithelial remodeling with is low, there are no available vivo data cells. Human umbilical cord blood contains hematopoietic nonhematopoietic cells, which been used clinically as an alternative to transplantation for hematologic malignancies other diseases.We hypothesized human might be effective injured...
Background Female athletes suffer a greater incidence of anterior cruciate ligament tears compared with male when participating in common sports; however, very little is known about the factors that explain this disparity. Study Design Case-control study; Level evidence, 3. Methods recreational alpine skiers an rupture and age-matched control provided serum sample self-reported menstrual history data immediately after injury. Both concentrations progesterone were then used to group subjects...
<h3>Importance</h3> Although evidence of antenatal steroids (ANS) efficacy at 22 to 25 weeks’ gestation is limited, increasingly these infants are treated with postnatal life support. <h3>Objectives</h3> To estimate the proportion receiving support who had exposure ANS, and examine if provision ANS was associated a higher rate survival hospital discharge without major morbidities. <h3>Design, Setting, Participants</h3> This multicenter observational cohort study consisted 33 472 eligible...
Preeclampsia is a multisystemic disorder of pregnancy that affects 250,000 pregnant individuals in the United States and approximately 10 million worldwide per annum. associated with substantial immediate morbidity mortality but also long-term for both mother offspring. It now clearly established low dose aspirin given daily, beginning early modestly reduces occurrence preeclampsia. Low-dose seems safe, because there paucity information about effects on infant, it not recommended all...
Objective: To determine the time course of plasma volume expansion in early pregnancy. Methods: We prospectively measured by Evans blue dye dilution during menstrual (cycle day 2–3), follicular 9–10), and luteal phases urinary leutinizing hormone [LH] surge plus 9–10) cycle at three additional points (LH + 16 days, LH 28 70 days) women achieving Twenty-one subjects were examined 38 cycles to establish baseline data. Ten conceived within 1 year studies. All ten pregnancies viable reached...
We report results from a pilot study examining the use of vouchers redeemable for retail items as incentives smoking cessation during pregnancy and postpartum. Of 100 study-eligible women who were still upon entering prenatal care, 58 recruited university-based community obstetric practices to participate in study. Participants assigned either contingent or noncontingent voucher conditions. Vouchers available 12 weeks In condition, earned biochemically verified abstinence. independent...
Female athletes suffer a higher incidence of anterior cruciate ligament injuries compared to their male counterparts, and they appear be at increased risk for these when have anterior-posterior knee laxity specific phases the menstrual cycle. Although mechanism by which factors combine increase injury is unclear, studies suggest that cyclic variations in joint produced hormone fluctuation during cycle predispose an athlete ligamentous injury. Little known about whether varies cyclically if...
Exposure to tobacco smoke, through both active and passive measures, has a significant impact on women's health, including effects the cardiovascular, pulmonary reproductive systems. Of particular interest is effect of smoking pregnancy outcomes. One crucial outcome that been linked subsequent development neonatal adult disease intrauterine or fetal growth restriction. In this article, we will summarize newborn size growth. We review evidence showing consumption during leads reduction in...
Circulating factors in preeclamptic women are thought to cause endothelial dysfunction and thereby contribute the progression of this hypertensive condition. Despite involvement neurological complications preeclampsia, there is a paucity data regarding effect circulating on cerebrovascular function. Using rat model pregnancy, we investigated blood-brain barrier permeability, myogenic activity, influence vasodilator mechanisms cerebral vessels exposed intraluminally plasma from normal...
Early-onset preeclampsia (EPE) is a severe form of that involves life-threatening neurological complications. However, the underlying mechanism by which EPE affects maternal brain not known. We hypothesized plasma from women with increases blood-brain barrier (BBB) permeability vs. late-onset (LPE) or normal pregnancy (NP) and investigated its perfusing cerebral veins nonpregnant rats (n=6–7/group) human EPE, LPE, NP measuring permeability. show significantly increased BBB LPE (P<0.001)....