A5022443645- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Substance Abuse Treatment and Outcomes
- Platelet Disorders and Treatments
- Smoking Behavior and Cessation
- Dementia and Cognitive Impairment Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Prostate Cancer Diagnosis and Treatment
- Surgical Simulation and Training
- Colorectal Cancer Surgical Treatments
- Renal cell carcinoma treatment
- Breast Cancer Treatment Studies
- Sexual function and dysfunction studies
- Cardiovascular Function and Risk Factors
- Pancreatic and Hepatic Oncology Research
- MRI in cancer diagnosis
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Pulmonary Hypertension Research and Treatments
- Urological Disorders and Treatments
- Cardiomyopathy and Myosin Studies
- Prostate Cancer Treatment and Research
- Amyotrophic Lateral Sclerosis Research
Mayo Clinic in Florida
2012-2024
Jacksonville College
2011-2024
WinnMed
2012-2024
Jacksonville University
2018
Heinrich Heine University Düsseldorf
2016
Mayo Clinic
2011-2015
Eastern Maine Medical Center
2012
University of Vermont
2007-2012
University of Vermont Medical Center
2006-2009
Yeshiva University
1992
<h3>Abstract</h3> Brain-machine interfaces (BMIs) hold promise for the restoration of sensory and motor function treatment neurological disorders, but clinical BMIs have not yet been widely adopted, in part because modest channel counts limited their potential. In this white paper, we describe Neuralink's first steps toward a scalable high-bandwidth BMI system. We built arrays small flexible electrode "threads", with as many 3,072 electrodes per array distributed across 96 threads. also...
Delay discounting (DD), a measure of impulsivity, describes the rate at which rewards lose value as delay to their receipt increases. Greater has been associated with cigarette smoking and various other types drug abuse in recent research. The present study examined whether DD predicts treatment outcome among smokers. More specifically, authors baseline for hypothetical monetary predicted status 24 weeks postpartum women who discontinued during pregnancy. Participants were 48 pregnant (10.5...
This study examined whether voucher-based reinforcement therapy (VBRT) contingent upon smoking abstinence during pregnancy is an effective method for decreasing maternal and improving fetal growth.A two-condition, parallel-groups, randomized controlled trial was conducted in a university-based research clinic. A total of 82 smokers entering prenatal care participated the trial.Participants were assigned randomly to either or non-contingent voucher conditions. Vouchers exchangeable retail...
<h3>Background</h3> The phosphorylated neurofilament heavy subunit (pNF-H), a major structural component of motor axons, is promising putative biomarker in amyotrophic lateral sclerosis (ALS) but has been studied mainly CSF. We examined pNF-H concentrations plasma, serum and CSF as potential for disease progression survival ALS. <h3>Methodology</h3> measured concentration by monoclonal sandwich ELISA plasma (n=43), (n=20) ALS patients collected at the Mayo Clinic Florida Emory University....
Clinical and neuropathological characteristics associated with G4C2 repeat expansions in chromosome 9 open reading frame 72 (C9ORF72), the most common genetic cause of amyotrophic lateral sclerosis (ALS) frontotemporal dementia, are highly variable. To gain insight on molecular basis for heterogeneity among C9ORF72 mutation carriers, we evaluated associations between features disease levels two abundantly expressed "c9RAN proteins" produced by repeat-associated non-ATG (RAN) translation...
Internet-based weight control programs have been showing promising results; however, as of yet, it is unclear which website components are critical for producing and maintaining loss. The aim this study to examine the utilization patterns a relationship Web features loss maintenance. One hundred twenty three (N = 123) participants took part in 12-month behavioral program over Internet their were monitored. When examining clustering feature loss, “feedback” factor (progress charts,...
Procedure length and agreement in detection of abnormalities may limit implementation chromoendoscopy (CE) for dysplasia surveillance ulcerative colitis (UC). We investigated these factors among endoscopists inexperienced this technique.Six investigators performed colonoscopy with white light endoscopy (WLE) followed by CE on 75 patients long-standing UC. Interobserver WLE images polyps nonpolypoid mucosa was determined. Withdrawal times from the cecum were compared based number...
We aimed to investigate the relationship between plasma and CSF progranulin (PGRN) levels.Plasma PGRN were measured in a cohort of 345 subjects from Mayo Clinic Study Aging by ELISA. Single nucleotide polymorphism genotyping was performed using TaqMan assays. Associations sex, age at sample collection, diagnosis, single genotypes (GRN, SORT1, APOE), Pittsburgh compound B score explored separately variable linear regression models. Pearson partial correlation coefficient used estimate...
The effect of screening on mortality from breast cancer has been evaluated in four intervention (experimental) studies with random assignment, one study nonrandom three case-control studies, and follow-up study. Each these showed a beneficial among women who were at least 45, 50, or 55 years old entry, but there is almost no information available the value more than 74 old. data are not helpful choosing interval within range 12-33 months, deciding whether to screen by mammography palpation...
Screening for the Muir-Torre variant of Lynch Syndrome (LS) using Mismatch Repair (MMR) gene immunohistochemistry (IHC) on sebaceous neoplasms (SNs) is technically feasible. To date, research into clinical utility MMR IHC this indication limited. We conducted a retrospective chart review 90 patients with completed at least one SN from January 2005 to May 2010. SNs included were adenomas, epitheliomas, carcinomas and basal squamous cell differentiation. Of patients, 13 (14 %) had genetically...
Limited data suggest that von Willebrand factor (VWF) abnormalities may accompany the high-shear state associated with prosthetic valve dysfunction. If true, laboratory testing could add value in quantifying prosthesis dysfunction and a pathophysiological explanation for acquired bleeding some patients.To determine whether dysfunctional prostheses are VWF compared normally functioning prostheses, to identify severity of abnormality relative other conditions, describe occurrence...
Object Management of idiopathic normal-pressure hydrocephalus (iNPH) is hard because the diagnosis difficult and shunt surgery has high complication rates. An important overdrainage, which often can be treated with adjustable–shunt valve manipulations but also may result in need for subdural hematoma evacuation. The authors evaluated overdrainage complications iNPH their relationship to lumbar puncture opening pressure (LPOP). Methods reviewed charts 164 consecutive patients who underwent at...
This study evaluated the efficacy of a contingency management (CM) intervention to promote smoking cessation in methadone‐maintained patients. Twenty participants, randomized into contingent ( n = 10) or noncontingent experimental conditions, completed 14‐day study. Abstinence was determined using breath carbon monoxide and urine cotinine levels. Contingent participants received voucher‐based incentives for biochemical evidence abstinence. Noncontingent earned vouchers independent status....
Objective: Self-monitoring is recommended following brief alcohol intervention (BI). We have previously demonstrated that self-monitoring with an automated telephone system (interactive voice response; IVR) associated a steady reduction in consumption the absence of BI. In this study we explore feasibility and efficacy IVR as possible therapeutic enhancement for Method: updated all providers (N= 112) 15 primary care clinics about BI encouraged them to do their patients whenever appropriate...
Abstract Objectives To determine whether use of a patient portal during hospitalization is associated with improvement in hospital outcomes, 30-day readmissions, inpatient mortality, and mortality. Materials Methods We performed retrospective propensity score–matched study that included all adult patients admitted to Mayo Clinic Hospital Jacksonville, Florida, from August 1, 2012, July 31, 2014, who had signed up for account prior (N = 7538). Results Out the account, 1566 (20.8%) accessed...
Abstract: Postoperative pain is a common complaint following living kidney donation or tumor resection using the laparoscopic hand-assisted technique. To evaluate potential analgesic benefit of transversus abdominis plane blocks, we conducted randomized, double-blind, placebo-controlled study in 21 patients scheduled to undergo elective living-donor nephrectomy single-sided for tumor. Patients were randomized receive either 20 mL 0.5% ropivacaine 0.9% saline bilaterally under ultrasound...