ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHighly stereoselective approaches to .alpha.- and .beta.-C-glycopyranosidesMichael D. Lewis, Jin Kun Cha, Yoshito KishiCite this: J. Am. Chem. Soc. 1982, 104, 18, 4976–4978Publication Date (Print):September 1, 1982Publication History Published online1 May 2002Published inissue 1 September 1982https://pubs.acs.org/doi/10.1021/ja00382a053https://doi.org/10.1021/ja00382a053research-articleACS PublicationsRequest reuse permissionsArticle...

A facile, efficient, and practical method for copper-catalyzed direct C-H amination of benzoxazoles with formamides or secondary amines has been developed. The system can be performed in the absence external base only requires O(2) even air as oxidant. variety substituted benzoxazol-2-amines were synthesized moderate to excellent yield.

A convenient method for preparing attractively functionalized 1,4-diketones has been devised by palladium-catalyzed cross-coupling of cyclopropanols and acyl chlorides. The utility this demonstrated in an enantioselective synthesis (+)-myrmicarin 217.

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTA New Variant of the Kulinkovich Hydroxycyclopropanation. Reductive Coupling Carboxylic Esters with Terminal OlefinsJinhwa Lee, Heejin Kim, and Jin Kun ChaView Author Information Department Chemistry, University Alabama Tuscaloosa, 35487 Cite this: J. Am. Chem. Soc. 1996, 118, 17, 4198–4199Publication Date (Web):May 1, 1996Publication History Received11 December 1995Published online1 May 1996Published inissue 1 January...

Reining in reactivity: Stereoselective SN2′ alkylation of cyclopropanols has been devised under the control mixed zinc/copper reagents. This method provides convenient access to enantiopure keto homoenolates which react with electrophiles (El+) form CC bonds. M=metal. Detailed facts importance specialist readers are published as ”Supporting Information”. Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted by authors. Please note: The publisher is...

A practical and ligand-free Cu-catalyzed decarboxylative trifluoromethylation of aryl iodides with sodium trifluoroacetate using Ag2O as a promoter was reported. variety trifluoromethyl-substituted aromatics are synthesized in moderate to excellent yields wide functional-group tolerance under relatively mild reaction conditions.

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTIntramolecular Hydroxycyclopropanation of ω-Vinyl Carboxylic EstersJinhwa Lee, Chul Hyun Kang, Heejin Kim, and Jin Kun ChaView Author Information Department Chemistry, University Alabama Tuscaloosa, 35487 Cite this: J. Am. Chem. Soc. 1996, 118, 1, 291–292Publication Date (Web):January 10, 1996Publication History Received5 September 1995Published online10 January 1996Published inissue 1 1996https://doi.org/10.1021/ja953055nCopyright © 1996...

Aromatic amines were conveniently, rapidly and, importantly, environmentally benignly prepared in excellent yields through chemoselective reduction of the corresponding aromatic nitro compounds with polymer-supported hydrazine hydrate presence iron oxide hydroxide catalyst.

The CO-displacement of [(μ-pdt)Fe2(CO)6] with (Ph2PCH2)2N(n-Pr) in refluxing toluene gave an unsymmetrical chelating complex [(μ-pdt){Fe(CO)3}{Fe(CO)(κ2-Ph2PCH2N(n-Pr)CH2PPh2}] (1) as a major product, together small amount the symmetrical intramolecular bridging [(μ-pdt){μ-Ph2PCH2N(n-Pr)CH2PPh2}{Fe(CO)2}2] (2) and intermolecular [{μ,κ1,κ1-Ph2PCH2N(n-Pr)CH2PPh2}{(μ-pdt)Fe2(CO)5}2] (3). In contrast, reaction (Ph2PCH2)2NR (R = n-Pr, Ph) afforded isomers 3 4 presence CO-removing reagent...

NCN-pincer (S,S)-2,6-bis(4′-isopropyl-2′-oxazolinyl)phenyl-ligated rare-earth-metal dichlorides [(S,S)-Phebox-iPr]LnCl2(THF)2 (Ln = Sc (1); Y (2); Dy (3); Ho (4); Tm (5); Lu (6)) were synthesized via transmetalation between [(S,S)-Phebox-iPr]Li and LnCl3 in THF solvent. Interestingly, treatment of LaCl3 by the same method generated tris(ligand) lanthanum complex [(S,S)-Phebox-iPr]3La (7). Molecular structures complexes 1, 2, 3, 7 established single-crystal X-ray diffraction study. Pincer...

A new and efficient method for palladium(II) catalytic desulfitative conjugate addition of arylsulfinic acids with α,β-unsaturated carbonyl compound has been developed. The key reacting intermediates including aryl Pd(II) sulfinic intermediate, Pd(II), C═O-Pd complexes were captured by ESI-MS/MS, which provide experimental evidence the understanding mechanism.

Alkynylation of cyclopropanols with 1-bromo-1-alkynes has been devised for easy access to synthetically useful alk-4-yn-1-ones. This method broadens the utility attractively functionalized as a new class homoenolate equivalent in C–C bond formation.

A novel and convenient photo-mediated halogenated spirocyclization of N-(p-methoxyaryl)propiolamides has been developed. The photolysis phenyliodine bis(trifluoroacetate) (PIFA) as an iodination reagent led to iodinated ipso-cyclization under the irradiation a xenon lamp, while brominated or chlorinated was achieved by irradiating mixture PIFA KBr/KCl blue LED. present protocol simply utilizes light safe clean energy source doesn't require any external photocatalyst providing various...

[reaction: see text] The palladium-mediated ring opening of substituted cyclopropanols has been found to take place predominantly at the less C-C bond. Thus, sequential application titanium-mediated cyclopropanation esters and resulting provides a convenient method for functionalizing monosubstituted olefins.

The stereocontrolled total synthesis of (−)-clavepictine A (1A) and (+)-clavepictine B (1B) has been accomplished in an enantioselective fashion, which unequivocally established the absolute configuration 1A 1B. pivotal step is diastereoselective silver(I)-promoted cyclization δ-amino allenes. Another key method includes cross-coupling enol triflates N-acyl lactams, allows functionalization otherwise unreactive lactams under mild conditions. utility Beak's α-lithiation-substitution chemistry...

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTNew Synthetic Method for Functionalized Pyrrolizidine, Indolizidine, and Mitomycin AlkaloidsJinhwa Lee, Jae Du Ha, Jin Kun ChaView Author Information Department of Chemistry, University Alabama Tuscaloosa, 35487 Cite this: J. Am. Chem. Soc. 1997, 119, 34, 8127–8128Publication Date (Web):August 27, 1997Publication History Received21 May 1997Published online27 August inissue 1...

Protonation of [{(mu-SCH2)2N(C6H4-p-NO2)}{Fe(CO)2(PMe3)}2] in the presence 4 equiv. HOTf afforded two species, a micro-hydride diiron complex, molecular structure which was crystallographically characterized, and micro-S-protonated readily deprotonated pyridine.

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXT1,2,3,4-Tetrahydro-8-hydroxyquinoline-Promoted Copper-Catalyzed Coupling of Nitrogen Nucleophiles and Aryl BromidesHuifeng Wang, Yaming Li*, Fangfang Sun, Yang Feng, Kun Jin, Xiuna WangView Author Information State Key Laboratory Fine Chemicals, Dalian University Technology, 116012, China[email protected]Cite this: J. Org. Chem. 2008, 73, 21, 8639–8642Publication Date (Web):October 9, 2008Publication History Received18 July 2008Published online9...