Linlin Jiang

ORCID: 0000-0001-9636-2281
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Research Areas
  • Ovarian function and disorders
  • Plant Stress Responses and Tolerance
  • Reproductive Biology and Fertility
  • MicroRNA in disease regulation
  • Blood Pressure and Hypertension Studies
  • Cancer-related molecular mechanisms research
  • Catalytic C–H Functionalization Methods
  • Liver Disease Diagnosis and Treatment
  • Light effects on plants
  • Plant nutrient uptake and metabolism
  • Plant Molecular Biology Research
  • Circular RNAs in diseases
  • Catalytic Cross-Coupling Reactions
  • Immune Response and Inflammation
  • Ginseng Biological Effects and Applications
  • Circadian rhythm and melatonin
  • Natural product bioactivities and synthesis
  • Multilevel Inverters and Converters
  • Advanced DC-DC Converters
  • Neuroscience of respiration and sleep
  • Pregnancy and preeclampsia studies
  • Traditional Chinese Medicine Analysis
  • Microgrid Control and Optimization
  • Quantum optics and atomic interactions
  • Phytochemistry and Biological Activities

Zhejiang Lab
2025

Zhejiang University
2025

Hunan Normal University
2025

Sun Yat-sen University
2015-2024

Chinese Academy of Agricultural Sciences
2013-2024

Harbin Medical University
2022-2024

Third Affiliated Hospital of Harbin Medical University
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2012-2024

Guang’anmen Hospital
2022-2024

Sun Yat-sen Memorial Hospital
2016-2024

Abstract In this study, a series of nanofibrous membranes were prepared from cellulose acetate (CA) and polyester urethane (PEU) using coelectrospinning or blend‐electrospinning. The drug release, in vitro antimicrobial activity vivo wound healing performance the nanofiber evaluated for use as dressings. To prevent common clinical infections, an agent, polyhexamethylene biguanide (PHMB) was incorporated into electrospun fibers. presence CA membrane improved its hydrophilicity permeability to...

10.1002/jbm.b.32724 article EN Journal of Biomedical Materials Research Part B Applied Biomaterials 2012-06-12

MicroRNAs (miRNAs) are small, noncoding RNAs that negatively regulate gene expression post-transcriptionally. Whether differently expressed miRNAs contribute to promoting granulosa cell proliferation in polycystic ovarian syndrome disease (PCOS) remains unknown.We explored whether certain involved the dysfunction of PCOS and mechanism increased cells proliferation. Patients Cells: miRNA was analyzed excised cortexes from 16 women with 8 non-PCOS. An immortalized human (KGN) used for...

10.1210/jc.2014-3827 article EN The Journal of Clinical Endocrinology & Metabolism 2015-02-19

<italic>In vivo</italic>imaging of hormone receptors provides the opportunity to visualize target tissues under hormonal control in live animals.

10.1039/c6sc04897h article EN cc-by-nc Chemical Science 2017-01-01

The epidemiology of valvular heart disease (VHD) has changed markedly over the last 50 years worldwide, and prevalence features VHD in China are unknown. objective this study was to investigate current status etiology China.We used a cross-sectional national survey with stratified multistage random sampling from general Chinese population estimate burden. Data on demographic characteristics, medical history, physical examination, blood tests, potential were collected. Echocardiography detect...

10.1186/s12872-021-02154-8 article EN cc-by BMC Cardiovascular Disorders 2021-07-13

Applying natural food additives extracted from plants is a sustainable development trend in the industry. Compared with synthetic additives, plant-based have garnered considerable attention owing to their advantages such as green safety, health, and environmental protection. Therefore, utilization of becoming most active field future direction for However, there are several problems associated large-scale production application, more studies required evaluate potential side effects safety...

10.1080/87559129.2022.2062764 article EN Food Reviews International 2022-04-13

Abstract Biodegradable porous Mg scaffolds are a promising approach to bone repair. In this work, 3D-spherical Mg–1.5Zn–0.2Ca (wt.%) were prepared by vacuum infiltration casting technology, and MgF 2 fluorapatite coatings designed control the degradation behavior of Mg-based scaffolds. The results showed that pores in composed main spherical (450–600 μm) interconnected (150–200 μm), porosity was up 74.97%. exhibited sufficient mechanical properties with compressive yield strength about 4.04...

10.1007/s10856-023-06754-y article EN cc-by Journal of Materials Science Materials in Medicine 2024-03-25

Chemical-looping combustion (CLC) is a very promising technology to combine the energy-utilization situation in China and CO2 zero-emission situ allowing for sequestration by efficient energy-saving ways without nitrogen oxide (NOx) formation. Having an oxygen carrier with sufficient reactivities reduction oxidation enough recyclability strength long-term operation one of key issues CLC process. This paper focuses on investigation Ni-based carriers coal char. First, Al(OC3H7)3 Ni(NO3)2 are...

10.1021/ef7003859 article EN Energy & Fuels 2008-02-20

Mesenchymal stem cells (MSCs) are an attractive candidate for cell-based therapy. We have designed a promising double-target therapeutic system non-Hodgkin's lymphoma (NHL) The is based on MSC homing capacity and scFvCD20 antigen-restriction to NHL. In this system, novel secreted fusion protein scFvCD20-sTRAIL, which contains CD20-specific single chain Fv antibody fragment (scFv) soluble tumor necrosis factor related apoptosis-inducing ligand (sTRAIL, aa residues 114-281) with isoleucine...

10.1021/mp300261e article EN Molecular Pharmaceutics 2012-11-02

Overexpression of tumor necrosis factor α (TNFα) is a hallmark many inflammatory diseases, including rheumatoid arthritis, bowel disease, and septic shock hepatitis, making it potential therapeutic target for clinical interventions. To explore chemical inhibitors against TNFα activity, we applied computer-aided drug design combined with in vitro cell-based assays identified lead compound, (E)-4-(2-(4-chloro-3-nitrophenyl) (named as C87 thereafter), which directly binds to TNFα, potently...

10.1074/jbc.m113.521708 article EN cc-by Journal of Biological Chemistry 2014-03-15

DNA methylation and repressive histone Histone3 Lysine9 (H3K9) dimethylation correlate with chromatin silencing in plants mammals. To identify factors required for H3K9 dimethylation, we screened suppressors of the repressor silencing1 (ros1) mutation, which causes expression RD29A (RESPONSE TO DESSICATION 29A) promoter-driven luciferase transgene (RD29A-LUC) 35S NPTII (NEOMYCIN PHOSPHOTRANSFERASE II) (35S-NPTII). We identified folylpolyglutamate synthetase FPGS1 known factor DECREASED...

10.1105/tpc.113.114678 article EN The Plant Cell 2013-07-01

A novel and convenient photo-mediated halogenated spirocyclization of N-(p-methoxyaryl)propiolamides has been developed. The photolysis phenyliodine bis(trifluoroacetate) (PIFA) as an iodination reagent led to iodinated ipso-cyclization under the irradiation a xenon lamp, while brominated or chlorinated was achieved by irradiating mixture PIFA KBr/KCl blue LED. present protocol simply utilizes light safe clean energy source doesn't require any external photocatalyst providing various...

10.1039/d0ob00057d article EN Organic & Biomolecular Chemistry 2020-01-01

Diabetic nephropathy (DN) and diabetic retinopathy (DR), as microvascular complications of diabetes mellitus, are currently the leading causes end-stage renal disease (ESRD) blindness, respectively, in adult working population, they major public health problems with social economic burdens. The parallelism between two process occurrence development manifests high overlap disease-causing risk factors pathogenesis, rates comorbidity, mutually predictive effects, partial concordance clinical...

10.3389/fendo.2024.1336123 article EN cc-by Frontiers in Endocrinology 2024-02-14

The implementation of quantum routers is an important and desired task in information science, since are components networks. Here, we propose a scheme for implementing single-photon waveguide-QED system, which consists two coupled two-level atoms to waveguides form four-port device. We obtain the exact analytical expressions scattering amplitudes using real-space method. By taking propagating time photons between coupling points into account or not, consider system working Markovian...

10.48550/arxiv.2502.10121 preprint EN arXiv (Cornell University) 2025-02-14

Zinc finger proteins were involved in response to different environmental stresses plant species. A typical Cys2/His2-type (C2H2-type) zinc gene GmZF1 from soybean was isolated and composed of 172 amino acids containing two conserved C2H2-type domains. Phylogenetic analysis showed that clustered on the same branch with six ZFPs dicotyledonous plants excepting for GsZFP1, distinguished those monocotyledon The protein localized at nucleus, has specific binding activity EP1S core sequence,...

10.1371/journal.pone.0109399 article EN cc-by PLoS ONE 2014-10-06
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