Irina Neguț

ORCID: 0000-0003-4038-7548
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Bone Tissue Engineering Materials
  • Dental materials and restorations
  • Nanoparticle-Based Drug Delivery
  • Laser-Ablation Synthesis of Nanoparticles
  • Electrospun Nanofibers in Biomedical Applications
  • Nanoparticles: synthesis and applications
  • Laser Applications in Dentistry and Medicine
  • Essential Oils and Antimicrobial Activity
  • Bacterial biofilms and quorum sensing
  • Advanced Drug Delivery Systems
  • Graphene and Nanomaterials Applications
  • Diamond and Carbon-based Materials Research
  • Polymer Surface Interaction Studies
  • Quantum Dots Synthesis And Properties
  • Titanium Alloys Microstructure and Properties
  • Wound Healing and Treatments
  • Metal and Thin Film Mechanics
  • Graphene research and applications
  • Nanoplatforms for cancer theranostics
  • Hydrogels: synthesis, properties, applications
  • Bee Products Chemical Analysis
  • 3D Printing in Biomedical Research
  • Advancements in Transdermal Drug Delivery
  • Antimicrobial Peptides and Activities
  • Additive Manufacturing and 3D Printing Technologies

National Institute for Laser Plasma and Radiation Physics
2016-2025

University of Bucharest
2016-2024

Bioactive glasses have developed into a variety of items that are used in order to treat wide range medical problems. Apart from being mostly applied the healing processes hard tissues, bioactive becoming very popular materials soft tissues healing. exhibited ability accelerate skin regeneration by enhancing angiogenesis and collagen deposition proliferation stage, as well positive effects on all other important stages wound They can adhere such bone aid those forming calcium–phosphate-like...

10.3390/app13106151 article EN cc-by Applied Sciences 2023-05-17

During surgery and after, pathogens can contaminate indwelling implanted medical devices, resulting in serious infections. Microbial colonization, infection, later biofilm formation are major complications associated with the use of implants represent risk factors implant failure. Despite fact that aseptic antimicrobial medications lower systemic antibiotic result a loss efficacy, increased tissue toxicity, development drug-resistant diseases. This work explores advancements coatings for...

10.3390/coatings14030256 article EN Coatings 2024-02-21

This review addresses the urgent need for more targeted and less toxic cancer treatments by exploring potential of multi-responsive polymersomes. These advanced nanocarriers are engineered to deliver drugs precisely tumor sites responding specific stimuli such as pH, temperature, light, hypoxia, redox conditions, thereby minimizing side effects associated with traditional chemotherapy. We discuss design, synthesis, recent applications polymersomes, emphasizing their ability improve...

10.3390/pharmaceutics16040463 article EN cc-by Pharmaceutics 2024-03-26

Graphene/CNT layers were deposited onto platinum electrodes of an interdigitated sensor using radio-frequency magnetron sputtering. The graphene/CNTs synthesized in Argon atmosphere at a pressure (2 × 10−2–5 10−3) mbar, with the substrate maintained 300 °C either through continuous heating electronically controlled heater or by applying −200 V bias direct current power supply throughout deposition process. study compares surface morphology, carbon atom arrangement within layer volumes, and...

10.3390/c11010009 article EN cc-by C – Journal of Carbon Research 2025-01-20

Globally, cancer is the second most common cause of death, and Europe accounts for almost 25% global burden, although its people make up only 10% world’s population. Conventional systemically administered anti-cancer drugs come with important drawbacks such as inefficiency due to poor bioavailability improper biodistribution, severe side effects associated low therapeutic indices, development multidrug resistance. Therefore, smart nano-engineered targeted drug-delivery systems tailored...

10.3390/pharmaceutics13091356 article EN cc-by Pharmaceutics 2021-08-28

Biofilms represent an increasing challenge in the medical practice worldwide, imposing a serious threat to public health. As bacterial strains have developed antibiotic resistance, researcher’s attention has been extensively focused on developing more efficient antimicrobial strategies. In this context, present study reports synthesis, physicochemical characterization, ex vivo biodistribution, and vitro evaluation of capacity nanostructured surfaces based zinc oxide (ZnO) biologically active...

10.3390/nano11102564 article EN cc-by Nanomaterials 2021-09-29

Since Graphene discovery, their associated derivate nanomaterials, Oxide (GO) and reduced-GO were in the forefront of continuous developments bio-nano-technology due to unique physical-chemical properties. Although GO nano-colloids (GON) proposed as drug release matrix for targeting cancer cells, there is still a concern regarding its cytotoxicity issues. In this study, we report on fabrication functional GON bio-coatings by Matrix-Assisted Pulsed Laser Evaporation (MAPLE) be used carriers...

10.3389/fchem.2020.00184 article EN cc-by Frontiers in Chemistry 2020-03-23

Aseptic loosening and periprosthetic infections are the main causes of implant failure. Strategies to mitigate this drawback therefore mandatory avoid primary revision replacement surgeries. A functional bioapatite–biopolymer double nanostructure fabricated by matrix-assisted pulsed laser evaporation prevent infection orthopedic dental implants could promote osseointegration ensure controlled delivery natural antimicrobial drugs. The synthesized consists two overlapping layers, lower from a...

10.3390/nano10020385 article EN cc-by Nanomaterials 2020-02-22

The occurrence of opportunistic local infections and improper integration metallic implants results in severe health conditions. Protective tunable coatings represent an attractive challenging selection for improving the devices’ biofunctional performances to restore or replace bone tissue. Composite materials based on hydroxyapatite (HAp), Kanamycin (KAN), fibroblast growth factor 2 (FGF2) are herein proposed as multifunctional hard tissue implants. superior cytocompatibility obtained...

10.3390/antibiotics10020160 article EN Antibiotics 2021-02-05
Coming Soon ...