- Osteoarthritis Treatment and Mechanisms
- Blood Pressure and Hypertension Studies
- Obesity, Physical Activity, Diet
- Cardiovascular and exercise physiology
- Global Cancer Incidence and Screening
- Heart Rate Variability and Autonomic Control
- Rheumatoid Arthritis Research and Therapies
- Cardiovascular Health and Disease Prevention
- Colorectal Cancer Screening and Detection
- Health Systems, Economic Evaluations, Quality of Life
- Physical Activity and Health
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Stroke Rehabilitation and Recovery
- Health disparities and outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Thyroid Disorders and Treatments
- Acute Ischemic Stroke Management
- Bariatric Surgery and Outcomes
- Musculoskeletal pain and rehabilitation
- Lower Extremity Biomechanics and Pathologies
- Workplace Health and Well-being
- Occupational and environmental lung diseases
- Intracranial Aneurysms: Treatment and Complications
- Diabetes, Cardiovascular Risks, and Lipoproteins
University of Tasmania
2015-2024
Menzies School of Health Research
2010-2023
Menzies Institute for Medical Research
2014-2022
University of East Anglia
2019
Norwich Research Park
2019
Royal Hobart Hospital
2018
Pham Ngoc Thach University of Medicine
2017-2018
Creative Commons
2018
GTx (United States)
2018
Monash University
2012-2017
Severe iodine deficiency (ID) during gestation is associated with neurocognitive sequelae. The long-term impact of mild ID, however, has not been well characterized. purpose this study was to determine whether children born mothers urinary concentrations (UICs) <150 μg/L pregnancy have poorer educational outcomes in primary school than peers whose did gestational ID (UIC ≥150 μg/L). This a longitudinal follow-up (at 9 years old) the Gestational Iodine Cohort. Pregnancy occurred period...
Arm cuff blood pressure (BP) may overestimate cardiovascular risk. Central aortic BP predicts mortality and could be a better method for patient management. We sought to determine the usefulness of central guide hypertension This was prospective, open-label, blinded–end point study in 286 patients with randomized treatment decisions guided by best-practice usual care (n=142; using office, home, 24-hour ambulatory BP) or, addition, intervention (n=144; SphygmoCor). Therapy reviewed every 3...
Background: The Motoric Cognitive Risk Syndrome (MCR) is characterized by slow gait speed and cognitive complaints. Objectives: objective of this study was to determine if the presence MCR increases risk falls in older people. Methods: Individual participant data (n = 6,204) from five longitudinal studies three countries were used for analysis. diagnosis defined as both objectively measured subjective complaints those without dementia or mobility disability. Falls prospectively ascertained...
Importance Knee osteoarthritis is disabling, with few effective treatments. Preliminary evidence suggested that krill oil supplementation improved knee pain, but effects on remain unclear. Objective To evaluate efficacy of supplementation, compared placebo, pain in people who have significant and effusion-synovitis. Design, Setting, Participants Multicenter, randomized, double-blind, placebo-controlled clinical trial 5 Australian cities. osteoarthritis, effusion-synovitis magnetic resonance...
To examine the association between depressive disorder and insulin resistance in a sample of young adults using Composite International Diagnostic Interview to ascertain depression status.Cross-sectional data were collected from 1,732 participants aged 26 36 years. Insulin was derived blood chemistry measures fasting glucose homeostasis model assessment method. Those identified with mild, moderate, or severe classified as having disorder.The 12-month prevalence 5.4% among men 11.7% women. In...
Objectives This study describes the longitudinal association between objectively assessed physical activity (PA) and knee structural change measured using MRI. Methods 405 community-dwelling adults aged 51–81 years were at baseline approximately 2.7 later. MRI of right follow-up was performed to evaluate bone marrow lesions (BMLs), meniscal pathology, cartilage defects, volume. PA by pedometer (steps/day). Results Doing ≥10 000 steps/day associated with BML increases (RR 1.97, 95% CI 1.19...
Background Waist circumference (WC) is an indicator of intra-abdominal adipose tissue, high levels which confer increased risk cardiometabolic disease. Population data on WC should be more informative than body mass index (BMI), a general size. This study aimed to evaluate the importance relative BMI in cross-sectional relationships with blood pressure (BP), glucose, and total cholesterol (TC) adult population Vietnam. Methods The were collected population-based survey conducted during...
Aim: We examined the combined effect of having multiple key risk factors and interactions between sclerosis (MS). Methods: performed an incident case-control study including cases with a first clinical diagnosis central nervous system demyelination (FCD) population-based controls. Results: Compared to those without any factors, one, two, three, four or five had increased odds being FCD case 2.12 (95% confidence interval (CI), 1.11–4.03), 4.31 CI, 2.24–8.31), 7.96 3.84–16.49), 21.24...
Background and Purpose— Women are reported to have poorer health-related quality of life (HRQoL) after stroke than men, but the underlying reasons uncertain. We investigated factors contributing sex differences. Methods— Individual participant data on 4288 first-ever strokes (1996–2013) were obtained from 4 high-quality population-based incidence studies Australasia Europe. HRQoL utility scores among survivors (range negative scores=worse death 1=perfect health) calculated 3 scales including...