Pei-Shan Chien

ORCID: 0000-0003-4072-5789
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About
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Research Areas
  • Plant Molecular Biology Research
  • Plant nutrient uptake and metabolism
  • Plant Stress Responses and Tolerance
  • Plant Gene Expression Analysis
  • Plant Micronutrient Interactions and Effects
  • Photosynthetic Processes and Mechanisms
  • Ovarian function and disorders
  • Liver Disease Diagnosis and Treatment
  • Plant-Microbe Interactions and Immunity
  • Dermatology and Skin Diseases
  • Herbal Medicine Research Studies
  • Legume Nitrogen Fixing Symbiosis
  • Urticaria and Related Conditions
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive Health and Technologies
  • Alcohol Consumption and Health Effects
  • Diet, Metabolism, and Disease

National Cheng Kung University
2024

Chi Mei Medical Center
2013-2024

Agricultural Biotechnology Research Center, Academia Sinica
2015-2023

Academia Sinica
2015

National Chung Hsing University
2015

High salinity has negative impacts on plant growth through altered water uptake and ion-specific toxicities. Plants have therefore evolved an intricate regulatory network in which hormones play significant roles modulating physiological responses to salinity. However, current understanding of the peptides involved this remains limited. Here, we identified a salt-regulated peptide Arabidopsis. The was 11 aa derived from C terminus cysteine-rich secretory proteins, antigen 5,...

10.1093/jxb/erv263 article EN cc-by Journal of Experimental Botany 2015-06-20

Phosphorus (P) is a mineral nutrient essential for plant growth and development, but most P in the soil unavailable plants. To understand genetic basis of acquisition regulation, we performed genome-wide association studies (GWASs) on diversity panel Arabidopsis (Arabidopsis thaliana). Two primary determinants were considered, namely, phosphate (Pi)-uptake activity PHOSPHATE TRANSPORTER 1 (PHT1) protein abundance. Association mapping revealed shared significant peak chromosome 5 (Chr5) where...

10.1093/plphys/kiac250 article EN cc-by-nc-nd PLANT PHYSIOLOGY 2022-05-27

Abstract Autophagy in plants is regulated by diverse signaling cascades response to environmental changes. Fine-tuning of its activity critical for the maintenance cellular homeostasis under basal and stressed conditions. In this study, we compared Arabidopsis autophagy–related (ATG) system transcriptionally inorganic phosphate (Pi) deficiency versus nitrogen showed that most ATG genes are only moderately upregulated Pi starvation, with relatively stronger induction AtATG8f AtATG8h among...

10.1093/pcp/pcad015 article EN Plant and Cell Physiology 2023-03-03

The Mendelian randomization approach uses genetic variants as instrumental variables to study the causal association between risk factors and health outcomes of interest. We aimed examine relation alcohol consumption cardiovascular using two variables: dehydrogenase 1B (

10.3389/fcvm.2024.1456777 article EN cc-by Frontiers in Cardiovascular Medicine 2024-10-02

Large-scale pharmaco-epidemiological studies of Chinese herbal medicine (CHM) for treatment urticaria are few, even though clinical trials showed some CHM effective. The purpose this study was to explore the frequencies and patterns prescriptions by analysing population-based database in Taiwan.This linked processed through complete traditional National Health Insurance Research Database Taiwan during 2009. We calculated used urticaria, which diagnosis defined as single ICD-9 Code 708....

10.1186/1472-6882-13-209 article EN cc-by BMC Complementary and Alternative Medicine 2013-08-15

Genome-wide association study (GWAS) has improved our understanding of complex traits, but challenges exist in distinguishing causation versus caused by linkage disequilibrium. Instead, transcriptome-wide studies (TWAS) detect direct associations between expression levels and phenotypic variations, providing an opportunity to better prioritize candidate genes. To assess the feasibility TWAS, we investigated transcriptomes, genomes, various traits Arabidopsis, including flowering time. The...

10.1093/jxb/erad262 article EN Journal of Experimental Botany 2023-07-08

Background In Taiwan there has been limited research of epidemiological surveys on prevalence infertility. This study aimed to provide the updated primary infertility and help-seeking among residents in Taiwan. Methods Between February March 2023, we conducted a cross-sectional population-based telephone survey 1,297 men women aged 20–49 years who were residing We used computer-assisted interviewing techniques collect data regarding sociodemographic reproductive characteristics. Using two...

10.1371/journal.pone.0306572 article EN cc-by PLoS ONE 2024-07-18

ABSTRACT To understand the genetic basis in governing phosphorus (P) acquisition, we performed genome-wide association studies (GWAS) on a diversity panel of Arabidopsis thaliana by two primary determinants P phosphate (Pi)-uptake activity and PHOSPHATE TRANSPORTER 1 (PHT1) protein abundance. Association mapping revealed shared significant peak chromosome 5 (Chr5) where PHT1;1 / 2 3 genes reside, suggesting strong correlation between regulation Pi-uptake PHT1 Genes encoding transcription...

10.1101/2022.01.05.475091 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-01-06

Abstract Genome-wide association study (GWAS) has improved our understanding of complex traits, but challenges exist in distinguishing causation versus caused by linkage disequilibrium. Instead, the transcriptome-wide (TWAS) detects direct associations between expression levels and phenotypic variations, providing an opportunity to better prioritize candidate genes. To assess feasibility TWAS, we investigated among transcriptomes, genomes, various including flowering time Arabidopsis ....

10.1101/2022.12.07.519424 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-12-10
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