A5087906921- RNA Interference and Gene Delivery
- Antimicrobial Peptides and Activities
- Immunotherapy and Immune Responses
- Phytochemical compounds biological activities
- Medicinal Plants and Bioactive Compounds
- Nanoparticle-Based Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Chromatography in Natural Products
- Tryptophan and brain disorders
- Effects of Radiation Exposure
- Natural Antidiabetic Agents Studies
- Circular RNAs in diseases
- Gut microbiota and health
- MicroRNA in disease regulation
- Computational Drug Discovery Methods
- Click Chemistry and Applications
- Biological Activity of Diterpenoids and Biflavonoids
- Ultrasound and Hyperthermia Applications
- Mesenchymal stem cell research
- Biochemical and Structural Characterization
- Neuroinflammation and Neurodegeneration Mechanisms
- Advanced biosensing and bioanalysis techniques
- Ovarian cancer diagnosis and treatment
- Fungal Biology and Applications
- Tissue Engineering and Regenerative Medicine
Taylor's University
2019-2024
Abstract The human gastrointestinal tract is populated with a diverse microbial community. vast genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every aspect biology, including health maintenance, development, aging, disease. advent new sequencing technologies culture-independent methods has allowed researchers to move beyond correlative studies toward mechanistic explorations shed light on microbiome–host interactions. Evidence unveiled bidirectional...
Micro-145 down-regulation is frequently found in breast cancers, indicating its potential as a therapeutic target. The introduction of exogenous miR-145 directly to the tumor sites has been hurdle due limited delivery, low bioavailability, and hence lower efficacy. Thus, this study aims synthesize characterize PEGylated liposome co-loaded with Dox-HCl mimics investigate in-vitro anti-proliferative activity against MDA-MB-231 cells. formulations were developed using composite central design...
Event Abstract Back to Antiproliferative effects of NDC2 and its analogues against human hepatocellular carcinoma (HepG2) cell line Sau Har Lee1*, Cheng Foh Le2 Chu Xin Ng1 1 School Biosciences, Taylor's University, Malaysia 2 University Nottingham Campus, Background Liver cancer is the second most common cause mortality from worldwide, with a incidence ratio as high 0.95. This mainly attributed multidrug resistance developed by liver cells after exposure conventional chemotherapies. Hence,...
According to tradition, plants and herbs are potential cures for numerous illnesses. In recent decades, they have gained worldwide recognition as critical sources of new drugs, especially cancer, the focus on medicinal plant research has increased tremendously. Currently, scientists attribute occurrence post-chemotherapy tumour exacerbation presence cancer stem cells hidden in bulk malignant tumour, forming a rare subpopulation that plays major role re-initiation, progression recurrence....
Background: Anticancer Peptides (ACPs) have received increasing attention as a promising class of novel anticancer agents owing to their potent and rapid cytotoxic properties. In this study, we aim investigate the effects cationicity hydrophobicity in modulating cytotoxicity PtxC, ACP from leafy mistletoe Phoradendron tomentosum against MDA-MB-231 Vero cells. Method: We designed series four PtxC analogues (PA1 – PA4) by residual substitutions with specific amino acids introduce charge...
Four human cell lines, one normal fibroblast and three tumour lines of differing radiosensitivities were evaluated for recovery from radiation damage, inhibition this by hyperthermia. The fibroblast, the glioma resistant ovarian carcinoma had about same resistance sublethal damage (SLDR) capacity. sensitive line a much lower SLDR potentially lethal repair (PLDR) capacity was greatest in least carcinoma. Hyperthermia 30 min at 43 degrees C resulted PLDR all lines. Heating immediately after...