Ajin Hu

ORCID: 0000-0003-4081-3076
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About
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Research Areas
  • Galectins and Cancer Biology
  • Caveolin-1 and cellular processes
  • Renal and related cancers
  • Cell Adhesion Molecules Research
  • Ovarian cancer diagnosis and treatment
  • Helicobacter pylori-related gastroenterology studies
  • E-commerce and Technology Innovations
  • Renal cell carcinoma treatment
  • Phagocytosis and Immune Regulation
  • Appendicitis Diagnosis and Management
  • Advanced Technology in Applications
  • Toxin Mechanisms and Immunotoxins
  • Glycosylation and Glycoproteins Research
  • Simulation and Modeling Applications
  • Probiotics and Fermented Foods
  • MRI in cancer diagnosis
  • Urinary and Genital Oncology Studies
  • Omental and Epiploic Conditions
  • Cancer, Hypoxia, and Metabolism
  • Erythrocyte Function and Pathophysiology
  • Intraperitoneal and Appendiceal Malignancies
  • Cancer Cells and Metastasis

Peking University
2013-2022

Peking University Third Hospital
2014-2022

Peking University Shougang Hospital
2020

Xi'an University of Architecture and Technology
2014

Aims Our aim was to analyse the utility of algorithm combining PAX8 with clinicopathological characteristics (tumour size, laterality and patient age) in differentiating primary ovarian mucinous tumours (POMTs) from extragenital metastatic carcinomas involving ovary (eMOMCs). Methods results Immunohistochemical staining for performed on formalin fixed, paraffin embedded tissues 47 POMTs, 18 eMOMCs 70 (ePMCs) using anti-PAX8 rabbit polyclonal antibody (pAb) monoclonal (mAb). positive signals...

10.1136/jclinpath-2015-202951 article EN cc-by-nc Journal of Clinical Pathology 2015-03-31

Abstract Epithelial ovarian cancer (EOC) is one of the leading causes death from gynecologic cancers and peritoneal dissemination major cause in patients with EOC. Although loss 4.1N associated increased risk malignancy, its association EOC remains unclear. To explore underlying mechanism constitutive activation epithelial-mesenchymal transition (EMT) matrix-detached cell resistance, we investigated samples 268 formalin-fixed tissues performed various vitro vivo assays. We report that...

10.1007/s13238-020-00723-9 article EN cc-by Protein & Cell 2020-05-25

Protein 4.1N (4.1N) is a member of the protein 4.1 family and essential for regulation cell adhesion, motility signaling. Previous studies have suggested that may serve tumor suppressor role. However, molecular mechanisms remain unclear. In current study, role in downregulation hypoxia‑induced factor 1α (HIF‑1α) under hypoxic conditions therefore suppression hypoxia induced epithelial‑mesenchymal transition (EMT) was investigated. The data were obtained from overexpressed knockdown...

10.3892/mmr.2015.4634 article EN Molecular Medicine Reports 2015-12-01

Renal cell carcinomas are usually unilateral. However, they bilateral in 2% to 4% of sporadic cases and is considerably more common familial cases. Synchronous multiple chromophobe renal carcinoma (CHRCC) with different subtypes rare.In this case report, we describe a synchronous CHRCC two histological variants, accompanied by clear cyst 50-year-old male. The patient underwent retroperitoneal laparoscopic nephron-sparing surgery there was no serious postoperative dysfunction.We report rare...

10.12998/wjcc.v8.i14.3064 article EN World Journal of Clinical Cases 2020-07-24
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