- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Soft tissue tumor case studies
- Ocular Surface and Contact Lens
- Spinal Fractures and Fixation Techniques
- Connexins and lens biology
- Dysphagia Assessment and Management
- Esophageal and GI Pathology
- Ear Surgery and Otitis Media
- Retinal Development and Disorders
- Cervical and Thoracic Myelopathy
- Flavonoids in Medical Research
- Systemic Sclerosis and Related Diseases
- Sarcoidosis and Beryllium Toxicity Research
- Ectopic Pregnancy Diagnosis and Management
- Ear and Head Tumors
- Spine and Intervertebral Disc Pathology
- Tumors and Oncological Cases
- Ophthalmology and Visual Impairment Studies
- Sarcoma Diagnosis and Treatment
- Biomedical Text Mining and Ontologies
- Cardiovascular Health and Disease Prevention
- Ergonomics and Musculoskeletal Disorders
Flinders University
2018-2025
Flinders Medical Centre
2017-2022
The University of Adelaide
2021
Royal Adelaide Hospital
2021
Abstract Background Effective clinical implementation of polygenic risk testing for glaucoma relies on healthcare professionals' attitudes and knowledge the test. Given emerging applications test, it will likely impact a range professionals require competency in scores concepts all those involved patient care. To our knowledge, this is first study to assess views towards glaucoma. Methods An online cross‐sectional questionnaire was distributed via relevant professional organisations...
Abstract Importance Monitoring the results of selective laser trabeculoplasty (SLT) on intraocular pressure (IOP) using a home rebound tonometry. Background To evaluate role Icare HOME tonometry in open‐angle glaucoma patients being treated with SLT. Design A clinic‐based prospective case study. Participants Fourteen eyes from 14 diagnosed primary were recruited. Methods The trabecular meshwork each eye was 360° frequency‐doubled Q‐switched Nd:YAG laser. IOP measured four times day for week...
Cataract and primary open-angle glaucoma (POAG) commonly co-exist, cataract surgery is thought to reduce intraocular pressure (IOP), the major modifiable risk factor of POAG.Previous studies exploring effect on IOP are limited by retrospective design, lack a control group, medication use washout loss follow up.Prospective, multicentre, matched case-control Australian study.171 eyes 108 POAG patients who underwent surgery, 171 eyes.Serial longitudinal measurements were compared before after...
Purpose: Pseudoexfoliation syndrome (PEX) is a common systemic disease that results in severe and often irreversible vision loss. Despite considerable research effort, PEX remains incompletely understood. This study sought to perform the first RNAseq elucidate pathophysiology of PEX, contribute publicly available transcriptomic data resource for future research. Methods: Human ocular lens capsular epithelium samples were collected from 25 patients with 39 non-PEX controls undergoing cataract...
Abstract Background Dysphagia post head and neck cancer (HNC) multimodality treatment is attributed to reduced pharyngeal strength. We hypothesized that tongue base augmentation for dysphagia (PAD therapy) would increase pressures during swallowing thereby improving swallow symptoms. Methods Adults with moderate–severe post‐HNC had PAD therapy using a temporary filler (hyaluronic acid [HA]), follow‐up long‐lasting lipofilling. Swallowing preprocedure postprocedure was assessed the Sydney...
Purpose: To assess the association between physical activity and spectral-domain optical coherence tomography (SD-OCT)–measured rates of macular thinning in an adult population with primary open-angle glaucoma. Methods: The correlation accelerometer-measured ganglion cell–inner plexiform layer (GCIPL) was measured 735 eyes from 388 participants Progression Risk Glaucoma: RElevant SNPs Significant Association (PROGRESSA) study. cross-sectional SD-OCT thickness then assessed 8862 6152...
Glaucoma and age-related macular degeneration (AMD) account for a substantial portion of global blindness. Both conditions are highly heritable, with recognised monogenic polygenic inheritance patterns. Current screening guidelines lack decisive recommendations. Polygenic risk scores (PRS) allow cost-effective broad population stratification these conditions. The predictive potential PRS could facilitate earlier diagnosis treatment, prevent unnecessary vision loss.The Genetic Risk Assessment...
A 36-year-old female patient was diagnosed with a parosteal lipoma arising from the left 3rd rib. This preluded by 5-year history of an asymptomatic and stable mass at medial aspect scapula. It had displayed interval enlargement in preceding 3 months which prompted investigation to rule out aggressive lesion. The investigated CT, MRI PET scan demonstrated well-circumscribed juxtacortical fatty osseous excrescence no enhancing soft tissue components or FDG avidity component, keeping lipoma....
The objective findings of phalangeal T2-weighted hyperintense and T1-weighted hypointense bone marrow signal on MRI without features seronegative arthropathy or osteomyelitis may assist clinicians in making a diagnosis the appropriate clinical context.
To evaluate the association between genetic risk for cardiovascular disease and retinal thinning in early glaucoma.Prospective, observational study.Multicohort study combining a cohort of patients with suspect manifest primary open-angle glaucoma (POAG), perimetric POAG, an external normative control cohort.A score was calculated 828 participants from Progression Risk Glaucoma: Relevant SNPs [single nucleotide polymorphisms] Significant Association (PROGRESSA) study. Participants were...
Abstract Background: Glaucoma and age-related macular degeneration (AMD) account for a substantial portion of global blindness. Both conditions are highly heritable, with recognised monogenic polygenic inheritance patterns. Current screening guidelines lack decisive recommendations. Polygenic risk scores (PRS) allow cost-effective broad population stratification these conditions. The predictive potential PRS could facilitate earlier diagnosis treatment, prevent unnecessary vision loss....