A5100699848- Antimicrobial Peptides and Activities
- Escherichia coli research studies
- Viral gastroenteritis research and epidemiology
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
- Cancer-related molecular mechanisms research
- Bacteriophages and microbial interactions
- Circular RNAs in diseases
- Antibiotic Resistance in Bacteria
- Intraocular Surgery and Lenses
- Pediatric health and respiratory diseases
- Connexins and lens biology
- MicroRNA in disease regulation
- Water Quality Monitoring Technologies
- Infant Nutrition and Health
- Anorectal Disease Treatments and Outcomes
- Ginseng Biological Effects and Applications
- Higher Education and Teaching Methods
- Engineering Education and Curriculum Development
- HVDC Systems and Fault Protection
- Vibrio bacteria research studies
- Ziziphus Jujuba Studies and Applications
- Neuropeptides and Animal Physiology
- Innovative Teaching Methods
- Click Chemistry and Applications
Xi'an Jiaotong University
2014-2025
Dalian Maritime University
2025
University of Maryland, Baltimore
2018-2019
Hubei Engineering University
2015
China Three Gorges University
2014
University of Strathclyde
2013
Institute of Cancer Research
2013
Chronic obstructive pulmonary disease (COPD) is a progressive, irreversible chronic inflammatory disorder typified by increased recruitment of monocytes, lymphocytes and neutrophils. Because this, as well the convenience peripheral blood nuclear cells (PBMCs) assessments, miRNA profiling PBMCs has drawn increasing attention in recent years for various disease. Therefore, we analyzed mRNA profiles to understand their regulatory network between COPD subjects versus smokers without airflow...
// Dan Xu 1, * , Bing Zhang Chongbing Liao 2 Wei 1 Weijia Wang Ying Chang Yongping Shao Key Laboratory of Biomedical Information Engineering the Ministry Education, Department Biological Science and Engineering, School Life Technology, Xi’an Jiaotong University, Xi’an, Shaanxi, China Center for Translational Medicine, Frontier Institute Xi'an Xi'an, These authors have contributed equally to this work Correspondence to: Shao, email: yongping.shao@xjtu.edu.cn Keywords: human...
Graphene has garnered significant attention due to its unique and remarkable properties. The widespread application of graphene materials in numerous fields inevitably leads their release into the environment. This study examines long-term impacts on anaerobic sequencing batch reactors. low-concentration (5 mg L-1) exhibited a inhibitory effect removal chemical oxygen demand, while high-concentration group (100 was less affected. transmission electron microscopy Raman spectroscopy results...
The type 3 secretion system (T3SS) found as cell-surface appendages of many pathogenic Gram-negative bacteria, although nonessential for bacterial survival, is an important therapeutic target drug discovery and development aimed at inhibiting virulence without inducing antibiotic resistance. We designed a fluorescence-polarization-based assay high-throughput screening mechanistically well-defined general strategy targeting the T3SS made serendipitous subset tanshinones—natural herbal...
Human α-defensins are 3- to 5-kDa disulfide-bridged peptides with a multitude of antimicrobial activities and immunomodulatory functions. Recent studies show that human enteric α-defensin 5 (HD5), host defense peptide important for intestinal homeostasis innate immunity, aids the highly infectious enteropathogen Shigella in breaching epithelium vitro vivo Whether how HD5 influences infection resident macrophages following its invasion remain poorly understood. Here, we report greatly...
Deficiency in biosynthesis of inner core lipopolysaccharide (LPS) rendered a characteristic biofilm-forming phenotype E.coli . The pathological implications this new Shigella flexneri , highly contagious enteric Gram-negative bacteria that is closely related to were investigated study. Δ rfaC (also referred as waaC ) mutant, with incomplete LPS due deficiency Hep biosynthesis, was strong biofilm formation ability and exhibited much more pronounced adhesiveness invasiveness human epithelial...
Human neutrophil peptides (HNPs), also known as human myeloid α-defensins degranulated by infiltrating neutrophils at bacterial infection loci, exhibit broad antomicrobial activities against bacteria, fungi, and viruses. We have made a surprising recent finding that Shigella, highly contagious, yet poorly adhesive enteric pathogen, exploits including HNP1 to enhance its adhesion invasion of host epithelial cells. However, the critical molecular determinants responsible for HNP1-enhanced...
The migration of lens epithelial cells towards the posterior capsule is a key event in development opacification (PCO). Accumulating evidence has described crosstalk between growth factors and adhesive signaling pathways wound healing cell migration. aim present study was to elucidate an aberrant transforming factor (TGF)‑β2 pathway that regulated pathological context PCO. expression fibronectin, focal adhesion kinase (FAK) phosphorylated (p)‑FAK HLE‑B3 following TGF‑β2 treatment determined...
This study focused on identifying possible new options derived from natural sources for the treatment of bacterial infections. Several products were investigated their potential in modulating Shigella-host-cell interactions. The proliferation Shigella sonnei was effectively inhibited inside HEp-2 cells presence 4-methoxycinnamic acid and propolin D. Propolin D also significantly reduced apoptosis infected macrophage-like U937 moderately secretion interleukin (IL)-1β IL-18, which probably...
Underwater active electrosense is bio-inspired by weakly electric fish that discharge and sense electrical information. Due to this biological mechanism, the fish's ability of navigation evasion are enhanced even in murky water. Previous researches about underwater mostly focus on localization shape recognition still object, but few detection object motion. This paper aims at providing a method direction identification moving target electrosense. We build model explain principle design array...
Double-circuit transmission lines parameters symmetry would affect the normal operation of and relay protection actions directly. This paper analyzes impacts three different phase sequence arrangements on conventional un-transposed double-circuit lines, requirements can be met by for with types length. Took practical engineering into consideration, a simple admissible suggestion transposition modes is given. The research results provide useful guidance reference future designs especially compact one.