A5025942220- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Probiotics and Fermented Foods
- Enzyme Production and Characterization
- Microbial Metabolism and Applications
- Food Quality and Safety Studies
- GABA and Rice Research
- Microbial Metabolites in Food Biotechnology
- Methane Hydrates and Related Phenomena
- Protein Hydrolysis and Bioactive Peptides
- Algal biology and biofuel production
- Gut microbiota and health
- Antioxidant Activity and Oxidative Stress
- Enzyme Catalysis and Immobilization
- Microbial Natural Products and Biosynthesis
- Bacteriophages and microbial interactions
- Carbohydrate Chemistry and Synthesis
- Identification and Quantification in Food
- Inflammatory Bowel Disease
- Coenzyme Q10 studies and effects
- Microbial Metabolic Engineering and Bioproduction
- Microscopic Colitis
- Plant biochemistry and biosynthesis
- Biochemical effects in animals
- Glycosylation and Glycoproteins Research
Incheon National University
2016-2025
Korea Food Research Institute
2012-2023
Bioengineering (Switzerland)
2018
Hanyang University Seoul Hospital
2015
Korea University of Science and Technology
2012
Brown University
2011
John Brown University
2011
Yonsei University
2005-2011
Dankook University
2003-2006
Fukuoka University
1993-1995
Abstract Haloarchaea produce bacterioruberin, a major C 50 carotenoid with antioxidant properties that allow for its potential application in the food, cosmetic, and pharmaceutical industries. This study aimed to optimize culture conditions total carotenoid, predominantly comprising production using Halorubrum ruber MBLA0099. A one-factor-at-a-time statistically-based experimental design were applied conditions. Culture optimized medium caused an increase from 0.496 1.966 mg L − 1 Maximal...
Abstract The occurrence of atopic dermatitis (AD), a chronic inflammatory skin disease, has been increasing steadily in children and adults recent decades. In this study, we evaluated the ability lactic acid bacterium Weissella cibaria WIKIM28 isolated from gatkimchi, Korean fermented vegetable preparation made mustard leaves, to suppress development AD induced by 2,4-dinitrochlorobenzene murine model. Oral administration W. reduced AD-like lesions, epidermal thickening, serum immunoglobulin...
The penM and pntM genes from the pentalenolactone biosynthetic gene clusters of Streptomyces exfoliatus UC5319 arenae TÜ469 were predicted to encode orthologous cytochrome P450s, CYP161C3 CYP161C2, responsible for final step in biosynthesis sesquiterpenoid antibiotic (1). Synthetic optimized expression Escherichia coli used obtain recombinant PenM PntM, each carrying an N-terminal His6-tag. Both proteins showed typical reduced-CO UV maxima at 450 nm, bound substrate, F (4), with KD values...
The pentalenolactone biosynthetic gene clusters have been cloned and sequenced from two known producers of the sesquiterpenoid antibiotic pentalenolactone, Streptomyces exfoliatus UC5319 arenae TÜ469. recombinant enzymes PenE PntE, S. arenae, respectively, catalyze flavin-dependent Baeyer-Villiger oxidation 1-deoxy-11-oxopentalenic acid (7) to D (8). Recombinant PenD, PntD, PtlD, latter avermitilis, each Fe(2+)-α-ketoglutarate-dependent (8) E (15) F (16). Incubation or PtlD with isomeric...
The glutamate decarboxylase of γ-aminobutyric acid-producing Lactobacillus brevis 877G (LbGAD) was expressed in Escherichia coli. optimal pH and temperature for the purified LbGAD activity were respectively determined to be 5.2 45 °C. CaCl2 shown a potent activator this activity. kinetic parameters Km value 3.6 mmol/L Vmax 0.06 mmol/L/min L-monosodium glutamate.
Abstract Background Lactococcus members belonging to lactic acid bacteria are widely used as starter in the production of fermented dairy products. From kimchi, a Korean food made vegetables , raffinolactis WiKim0068 was isolated and its genome analyzed . Results The complete strain consists one chromosome two plasmids that comprises 2,292,235 bp, with G + C content 39.7 mol%. Analysis orthoANI values among sequences showed has > 67% sequence similarity other species subspecies. In...