A5107093054- Tracheal and airway disorders
- Airway Management and Intubation Techniques
- Ear Surgery and Otitis Media
- Sarcoma Diagnosis and Treatment
- Tumors and Oncological Cases
- Oral and Maxillofacial Pathology
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Oral and Craniofacial Lesions
- Salivary Gland Tumors Diagnosis and Treatment
- Congenital Ear and Nasal Anomalies
- Craniofacial Disorders and Treatments
- Nasal Surgery and Airway Studies
- Foreign Body Medical Cases
- Soft tissue tumors and treatment
- Head and Neck Anomalies
- Immune Cell Function and Interaction
- Hearing Loss and Rehabilitation
- Neurofibromatosis and Schwannoma Cases
- Respiratory Support and Mechanisms
- Single-cell and spatial transcriptomics
- Esophageal and GI Pathology
- Reconstructive Facial Surgery Techniques
- Cleft Lip and Palate Research
- Infectious Diseases and Tuberculosis
Children's Hospital of Philadelphia
1995-2024
University of Pennsylvania
1995-2024
University of Alabama at Birmingham
2001
Philadelphia University
1983-1999
University of California, Los Angeles
1981
Stanford Medicine
1981
Stanford University
1981
The mechanisms by which FOXP3+ T follicular regulatory (Tfr) cells simultaneously steer antibody formation toward microbe or vaccine recognition and away from self-reactivity remain incompletely understood. To explore underappreciated heterogeneity in human Tfr cell development, function, localization, we used paired TCRVA/TCRVB sequencing to distinguish tonsillar that are clonally related natural (nTfr) those likely induced helper (Tfh) (iTfr). proteins iTfr nTfr differentially expressed...
Pilomatrixomas are benign skin neoplasms of hair follicle origin. They one the most common superficial masses head and neck excised in children. Although entity has been well studied literature, few studies have undertaken to evaluate clinical characteristics pilomatrixomas specifically The purpose this study was review management children presenting with at a large tertiary care pediatric hospital.A retrospective chart performed all patients histologically confirmed pilomatrixoma during...
Abstract The proper management of patients with orbital and periorbital cellulitis represents a distinct challenge to the clinician. A retrospective study is presented 165 diagnosis or admitted Children's Hospital Philadelphia (CHOP) from January 1975 through December 1980. Sinusitis, trauma, local skin inflammations, otitis were most common etiologies. Twenty‐three had cellulitis, all which secondary sinusitis. There was one death in this series. No permanent ocular sequelae related...
Controversy exists regarding the management of middle meatus after pediatric functional endoscopic sinus surgery (FESS). To prevent adhesions following FESS, gelatin film stenting has been recommended. The effects stenting, however, have not established. Fifty-one children with similar degrees bilateral disease had a stent placed in one on completion while opposite was stented. Two to three weeks later at time second, staged procedure, sides were compared for presence stent, adhesions,...
Abstract The otolaryngologist who treats children must have knowledge of the neoplasms that can occur in childhood. Such tumors are usually mesenchymal origin and may be benign or malignant. Diagnosis management more common undertaken by because local excision is generally curative. proper treatment malignant lesions requires a extensive, multidisciplinary team, which includes pediatric oncologist, diagnostic therapeutic radiologist, pathologist, addition to otolaryngologist. purposes this...
Examination of the child's larynx is mandatory in management pediatric airway problems. The techniques used to perform this examination have evolved over time and now present specialist with choices that can be tailored each specific situation. Traditionally, rigid direct laryngoscopy (RDL) has been evaluate larynx. More recently, flexible fiberoptic (FFL) visualize airway. RDL FFL play a role evaluation Expertise both for otolaryngologist managing respiratory disorders children. become our...
To investigate whether gross motor skills in preschool-aged children 24 to 60 months old with otitis media effusion (OME) are different from those of preschool without OME.The portion the Peabody Developmental Motor Scales (PDMS-GM) was used compare 13 OME before and after tympanostomy tube placement 12 had significantly reduced scores preoperatively compared on PDMS-GM. After surgery, higher than OME, indicating an accelerated rate development.Balance development additional factors be...
Non-tuberculous mycobacterial (NTM) infection is the most common cause of granulomatous inflammation in pediatric neck masses. Diagnosis relies upon culture, acid-fast bacilli (AFB) staining, chest radiograph, purified protein derivative (PPD) test, and clinical features. Computed tomography (CT) magnetic resonance (MR) imaging may provide valuable information work-up children with cervical We reviewed 11 CT 5 MR studies a diagnosis NTM infection. Specific findings included stranding...
The etiology, clinical presentation, and therapeutic strategies associated with membranous laryngotracheobronchitis are discussed. A case is presented in which a lateral neck radiograph gave the preliminary impression of tracheal foreign body. Endoscopic examination upper airway revealed correct diagnosis acute laryngotracheobronchitis. Comparison more commonly occurring viral made.