Mengyuan Xiao

ORCID: 0000-0003-4102-794X
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About
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Research Areas
  • Extracellular vesicles in disease
  • Pulmonary Hypertension Research and Treatments
  • MicroRNA in disease regulation
  • Cardiovascular Disease and Adiposity
  • Mesenchymal stem cell research
  • Organ Transplantation Techniques and Outcomes
  • Liver physiology and pathology
  • Cerebral Venous Sinus Thrombosis
  • Intraocular Surgery and Lenses
  • Blood Pressure and Hypertension Studies
  • Glaucoma and retinal disorders
  • Renin-Angiotensin System Studies
  • Cardiovascular Health and Risk Factors
  • Nutritional Studies and Diet

Guangdong Medical College
2014-2023

First Affiliated Hospital of Jinan University
2023

Guangdong Academy of Medical Sciences
2023

Guangdong Provincial People's Hospital
2023

Dalian University
2013

Introduction & Objective Microvesicles (MVs) derived from mesenchymal stem cells (MSCs) have been shown to promote angiogenesis. This study was aimed shed a light on the mechanisms by analyzing angiogenesis-promoting compositions of MSC-MVs. Also we try figure out impact hypoxia Methods MVs were isolated culture supernatants MSCs under hypoxia/normoxia and serum-deprivation condition. The morphological features revealed an electron microscope origin identified bead-bound assay. An antibody...

10.1371/journal.pone.0115316 article EN cc-by PLoS ONE 2014-12-16

The renin-angiotensin system (RAS) has been suggested to play an important role in cardiac remodeling after acute myocardial infarction (AMI). We have confirmed that bone marrow mesenchymal stem cell-derived exosomes (BMSC-EX) had similar types of repair like effects upon tissues as BMSC, but the mechanisms remain unknown. BMSC were cultured third generation and induced release exosomes. Rats injected with (100 μg/mL) or cells (1 × 106/mL) through tail vein immediately AMI was built,...

10.1089/scd.2020.0132 article EN Stem Cells and Development 2021-03-26

The association of adiposity indices with prehypertension remains unclear in the Chinese non-hypertensive population. This study aimed to compare indices, including waist circumference (WC), waist-to-height ratio, body roundness index (BRI), a shape (ABSI), and conicity (CI), We recruited 61 475 participants from population-based screening project Guangdong province, China. Multiple logistic regression analyses were performed detect between six prehypertension. Receiver operator...

10.1111/jch.14622 article EN cc-by-nc-nd Journal of Clinical Hypertension 2023-03-27

Objective To study the reasons,treatment and prevention of anterior chamber disappearance with high intraocular pressure during cataract phacoemulsification.Methods Of simply age-related in our hospital' s Ophthamology Dept.,67 cases (67 eyes) happened phacoemulsification.Operation process suspended for 4 cases,immediately intravenous injection 20% mannital 250 ml.Intraocular lowered 1 hour later.Reconstruct viscoelastic agent to complete operation safely.For 3 cases,insert needle through...

10.3760/cma.j.issn.2095-1477.2013.04.016 article EN Yanwaishang zhiye yanbing zazhi 2013-04-25
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