Yuhong Jiang

ORCID: 0000-0003-4104-4029
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About
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Research Areas
  • Cancer Cells and Metastasis
  • Ferroptosis and cancer prognosis
  • 3D Printing in Biomedical Research
  • Cancer, Lipids, and Metabolism
  • Pelvic and Acetabular Injuries
  • Colorectal Cancer Surgical Treatments
  • Cancer Genomics and Diagnostics
  • Single-cell and spatial transcriptomics
  • Diverticular Disease and Complications
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Tissue Engineering and Regenerative Medicine
  • RNA Interference and Gene Delivery
  • Gallbladder and Bile Duct Disorders
  • Cancer, Hypoxia, and Metabolism

Hunan University
2024

Shenzhen University
2024

University of Manchester
2024

Second Xiangya Hospital of Central South University
2022-2023

Central South University
2022-2023

Abstract The potential for tumor occurrence triggered by cancer stem cells (CSCs) has emerged as a significant challenge human colorectal therapy. However, the underlying mechanism of CSC development remains controversial. Our study provided evidence that bulk could dedifferentiate to CSCs and reacquire CSC‐like phenotypes if cultured in presence extracellular matrix reagents, such Matrigel fibrin gels. In these 3D gels, CD133 − can regain tumorigenic stem‐like phenotypes. Mechanistically,...

10.1111/cas.15548 article EN Cancer Science 2022-09-02

Background: Chromosome 5 open reading frame 46 ( C5ORF46 ), also known as antimicrobial peptide with 64 amino acid residues AP-64 ) and skin saliva-secreted protein 1 SSSP1 belongs to the family of genes encodes a small exosomal protein. has been implicated in antibacterial activity associated patient prognosis pancreatic cancer, colorectal stomach cancer. These findings highlight importance gastrointestinal (GI) tumor inception development. However, prognostic immunological value human GI...

10.3389/fgene.2022.926943 article EN cc-by Frontiers in Genetics 2022-08-05

Abstract Melanoma is a malignant neoplasia of pigment-producing melanocytes notable for its ability to metastasize early during primary tumor growth. Melanomas display typically high mutation burden—a hallmark associated with immune checkpoint blockade therapy (ICBT) sensitivity—but can still evade ICBT. These melanoma phenotypes likely relate embryonic neural crest cells, population cells from which arise. For instance, BRAF inhibition-evading adopt crest-like states. However, the exact...

10.1158/1538-7445.am2024-lb233 article EN Cancer Research 2024-04-05

Schematic representation of RHLC. dLECMs were obtained from porcine liver decellularization. HepG2, TEC, CAF, and JURKAT cells mixed co-cultured on dLECMs.

10.1039/d4bm00754a article EN Biomaterials Science 2024-10-31

Abstract Objective To compare and analyze the differences in safety, feasibility short-term efficacy between robot-assisted totally robotic surgery Right Hemicolectomy. Methods A retrospective analysis was conducted on clinical data of 184 patients who underwent right hemicolectomy The Second Xiangya Hospital Central South University from July 2016 to December 2021. 148 were matched (including 74 cases (TRAH) (TRRH)). general information, surgical pathological results complications collected...

10.21203/rs.3.rs-1940959/v1 preprint EN cc-by Research Square (Research Square) 2022-08-11
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