Lun Li

ORCID: 0000-0003-3242-031X
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About
Contact & Profiles
Research Areas
  • Nuclear Physics and Applications
  • Nuclear reactor physics and engineering
  • Radiation Detection and Scintillator Technologies
  • Radiation Therapy and Dosimetry
  • Gene expression and cancer classification
  • Genomics and Phylogenetic Studies
  • Advanced machining processes and optimization
  • Manufacturing Process and Optimization
  • Advanced Numerical Analysis Techniques
  • Electron and X-Ray Spectroscopy Techniques
  • Advanced Surface Polishing Techniques
  • RNA and protein synthesis mechanisms
  • Advanced Electron Microscopy Techniques and Applications
  • Molecular Biology Techniques and Applications
  • Breast Cancer Treatment Studies
  • Climate variability and models
  • Reconstructive Surgery and Microvascular Techniques
  • Ocean Waves and Remote Sensing
  • Bioinformatics and Genomic Networks
  • Nuclear physics research studies
  • Radar Systems and Signal Processing
  • Seismic Imaging and Inversion Techniques
  • Genetic Mapping and Diversity in Plants and Animals
  • Breast Implant and Reconstruction
  • Hydrocarbon exploration and reservoir analysis

Second Xiangya Hospital of Central South University
2016-2025

Central South University
2016-2025

Chinese Academy of Sciences
2014-2024

Beijing Normal University
2023-2024

University of Pennsylvania
2024

Jiangnan University
2022-2024

Wuhan Puai Hospital
2024

Nanjing Tech University
2023-2024

Shanghai Center For Bioinformation Technology
2024

Jianghan University
2016-2024

Single-layer single-crystalline SnSe nanosheet with four-atomic thickness of ∼1.0 nm and lateral size ∼300 is presented here by using a one-pot synthetic method. It found that 1,10-phenanthroline plays an important role in determining the morphology product as three-dimensional nanoflowers are obtained absence while keeping other reaction parameters same. The evolution process study discloses nanosheets from coalescence nucleus orientated attachment mechanism. Band gap determination...

10.1021/ja3108017 article EN Journal of the American Chemical Society 2013-01-12

The majority of breast cancer patients die metastasis rather than primary tumors, whereas the molecular mechanisms orchestrating remains poorly understood. Long noncoding RNAs (lncRNA) have been shown to regulate occurrence and progression. However, lncRNAs that drive in their underlying are still largely unknown.lncRNAs highly expressed metastatic lymph nodes were identified by microarray. Survival analysis made Kaplan-Meier method. Cell proliferation, migration, invasion assay was...

10.1186/s12943-019-1115-y article EN cc-by Molecular Cancer 2019-12-01

Abstract The National Genomics Data Center (NGDC), which is a part of the China for Bioinformation (CNCB), provides family database resources to support global academic and industrial communities. With rapid accumulation multi-omics data at an unprecedented pace, CNCB-NGDC continuously expands updates core through big archiving, integrative analysis value-added curation. Importantly, NGDC collaborates closely with major international databases initiatives ensure seamless exchange...

10.1093/nar/gkad1078 article EN cc-by Nucleic Acids Research 2023-11-29

Abstract APETALA2/ethylene-responsive element binding protein (AP2/EREBP) transcription factors constitute one of the largest and most conserved gene families in plant play essential roles growth, development stress response. Except a few members, AP2/EREBP family has not been characterized Brachypodium distachyon , model Poaceae. We performed genome-wide study this B. by phylogenetic analyses, transactivation assays transcript profiling. A total 149 genes were identified divided into four...

10.1038/srep21623 article EN cc-by Scientific Reports 2016-02-12

The National Genomics Data Center (NGDC), which is a part of the China for Bioinformation (CNCB), offers comprehensive suite database resources to support global scientific community. Amidst unprecedented accumulation multi-omics data, CNCB-NGDC committed continually evolving and updating its core through big data archiving, integrative analysis value-added curation. Over past year, has expanded collaborations with international databases established new subcenters focusing on biodiversity,...

10.1093/nar/gkae978 article EN cc-by Nucleic Acids Research 2024-11-11

M3Al-layered double hydroxide (LDH, M = Mg, Ni, Co) supported Au nanoclusters (AuNCs) catalysts have been prepared for the first time by using water-soluble glutathione-capped as precursor. Detailed characterizations show that ultrafine (ca. 1.5 ± 0.6 nm) were well dispersed on surface of LDH with a loading below ∼0.23 wt% upon synergetic interaction between AuNCs and M3Al-LDH. AuNCs/Mg3Al-LDH-0.23 exhibits much higher catalytic performance oxidation 1-phenylethanol in toluene than...

10.1039/c3nr05604j article EN Nanoscale 2014-01-01

Abstract The annual cycle of extra-tropical surface air temperature is an important component the Earth’s climate system. Over past decades, a reduced amplitude this mode has been observed in some regions. Although attributed to anthropogenic forcing, it remains unclear when dampening started. Here we use residual series tree-ring width and maximum latewood density from Tibetan Plateau >4,000 m asl reconstruct changes seasonality over three centuries. new proxy evidence suggests that...

10.1038/ncomms14008 article EN cc-by Nature Communications 2017-01-17

A method for extracting sea surface wind direction information from bistatic high-frequency (HF) radar Doppler spectra is presented. By analogy to the monostatic case, ratio of intensities positive and negative Bragg peaks used derive (ambiguous) direction. For operation, reference taken with respect scattering ellipse normal rather than beam The shown be valid based on simulated HF spectra. Wind also extracted data collected Southern China coast. Comparison between radar-measured directions...

10.1109/tgrs.2012.2188298 article EN IEEE Transactions on Geoscience and Remote Sensing 2012-09-21

Plant bugs (Miridae species), which are sap-sucking insects, have emerged as major pests of cotton in China. Most Miridae species not sensitive to commercial Bacillus thuringiensis (Bt) cotton, resulting significant economic losses and an increased application insecticide, eventually may compromise the future Bt cotton. We demonstrate that FATTY ACYL-COA REDUCTASE (AsFAR) plays essential role reproduction bug Adelphocoris suturalis. Down-regulation AsFAR expression by injection...

10.1111/nph.14636 article EN New Phytologist 2017-06-13

Abstract A large number RNAs are enriched and stable in extracellular vesicles (EVs), they can reflect their tissue origins suitable as liquid biopsy markers for cancer diagnosis treatment efficacy prediction. In this study, we used vesicle long RNA (exLR) sequencing to characterize the plasma-derived exLRs from 112 breast patients, 19 benign patients 41 healthy participants. The different profiling was found between non-cancer groups. Thus, constructed a diagnostic signature which showed...

10.1038/s41523-021-00356-z article EN cc-by npj Breast Cancer 2021-12-10

Fufang Zhenzhu Tiao Zhi (FTZ) formula is a Chinese herbal preparation used in the clinical treatment of disorders glucolipid metabolism. Given its effective actions on regulation lipid dysfunction and anti-inflammatory antioxidative effects, we designed this study to investigate cardioprotective effect possible mechanism FTZ diabetic cardiomyopathy (DCM) mice.FTZ was administered mice by oral gavage daily at dose 1.2 g/kg or 2.4 bodyweight for 8 weeks. Doppler echocardiography, H&E, WGA...

10.1016/j.biopha.2022.112709 article EN Biomedicine & Pharmacotherapy 2022-02-18

Abstract Enantioenriched N -alkylindole compounds, in which nitrogen is bound to a stereogenic sp 3 carbon, are an important entity of target molecules the fields biological, medicinal, and organic chemistry. Despite considerable efforts aimed at inventing methods for stereoselective indole functionalization, straightforward access diverse range chiral -alkylindoles intermolecular catalytic fashion from readily available substrates remains ongoing challenge. In sharp contrast existing C–N...

10.1038/s41467-022-34615-9 article EN cc-by Nature Communications 2022-11-11

Abstract Based on temperature data from 79 meteorological stations, we estimate the warming rate by season Tibetan Plateau (TP) during 1984–2013. The was spatially heterogeneous across seasons over past 30 years. northern TP (NTP) experienced more than southern (STP) (divided near 33°N) in all seasons. greatest north-south difference 0.70 ± 0.11 °C for summer (June-August), while smallest 0.27 0.14 cold (November-April). Such seasonal and spatial heterogeneity is consistent with...

10.1038/srep11725 article EN cc-by Scientific Reports 2015-06-26
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