A5083717200- Nanoparticles: synthesis and applications
- Advanced Nanomaterials in Catalysis
- Geochemistry and Elemental Analysis
- Dark Matter and Cosmic Phenomena
- Carbon and Quantum Dots Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Heavy Metal Exposure and Toxicity
- Nuclear Physics and Applications
- Graphene and Nanomaterials Applications
- Heavy metals in environment
- Astrophysics and Cosmic Phenomena
- Particle Detector Development and Performance
- Trace Elements in Health
- Radioactive element chemistry and processing
- Plant nutrient uptake and metabolism
- Geological and Geochemical Analysis
- Soil Carbon and Nitrogen Dynamics
- Radiation Therapy and Dosimetry
- Nanoplatforms for cancer theranostics
- Constructed Wetlands for Wastewater Treatment
- Geochemistry and Geologic Mapping
- Nanoparticle-Based Drug Delivery
- Plant Stress Responses and Tolerance
- Mercury impact and mitigation studies
Shandong Sport University
2023-2025
Institute of High Energy Physics
2016-2025
Chinese Academy of Sciences
2016-2025
University of Chinese Academy of Sciences
2014-2025
East China University of Science and Technology
2025
University of Hong Kong
2019-2025
Shanghai Jiao Tong University
2017-2025
University of California, San Diego
2021-2025
North China University of Science and Technology
2025
Beijing University of Agriculture
2018-2024
Before researchers apply nanomaterials (NMs) in biomedicine, they need to understand the blood circulation and clearance profile of these materials vivo. These qualities determine balance between nanomaterial-induced activity unwanted toxicity. NMs have heterogeneous characteristics: combine bulk properties solids with mobility molecules, their highly active contact interfaces exhibit diverse functionalities. Any new unexpected features patterns are great concern toxicological studies...
Biotransformation is a critical factor that may modify the toxicity, behavior, and fate of engineered nanoparticles in environment. CeO2 (NPs) are generally recognized as stable under environmental biological conditions. The present study aims to investigate biotransformation NPs plant systems. Transmission electron microscopy (TEM) images show needlelike clusters on epidermis intercellular spaces cucumber roots after treatment with 2000 mg/L for 21 days. By using soft X-ray scanning...
Ceria nanoparticles (nano-CeO2), due to their widespread applications, have attracted a lot of concern about toxic effects on both human health and the environment. The present work aimed evaluate in vivo nano-CeO2 (8.5 nm) Caenorhabditis elegans (C. elegans) at environmental relevant concentrations (molar ranging from 1 nM 100 nM). results indicate that could induce ROS accumulation oxidative damage C. elegans, finally lead decreased lifespan. most surprising thing is mean lifespan...
Heavy metal pollution is not only a hazard to living organisms but also an important worldwide environmental concern. Experiments were performed investigate the physiological mechanisms of magnetic (Fe3O4) nanoparticles (nano-Fe3O4) mitigation toxicity heavy metals (Pb, Zn, Cd and Cu) in wheat seedlings. All Petri dishes with germinating seedlings (1d) covered, sealed parafilm, placed dark growth chamber. parameters (seedling inhibition, accumulation, enzymatic activities, reducing effects...
The presence and release of nanoparticles (NPs) into the environment have important implications for human health environment. A critical aspect risk assessment is to understand interactions manufactured with plants. In this study, uptake distribution characteristics two types ceria sizes ca. 7 nm 25 in cucumber plants were investigated using a radiotracer method other techniques. With increasing concentration nanoparticles, dependent absorption by plant roots was noticed, but majority...
Reactive oxygen species (ROS)-based therapeutic modalities including chemodynamic therapy (CDT) and photodynamic (PDT) hold great promise for conquering malignant tumors. However, these two methods tend to be restricted by the overexpressed glutathione (GSH) hypoxia in tumor microenvironment (TME). Here, we develop biodegradable copper/manganese silicate nanosphere (CMSN)-coated lanthanide-doped nanoparticles (LDNPs) trimodal imaging-guided CDT/PDT synergistic therapy. The tridoped...
Abstract Ceria nanoparticles (nanoceria) are well known as a superoxide scavenger. However, inherent superoxide‐scavenging ability has only been found in the nanoceria with sizes of less than 5 nm and very limited shape diversity. Reported herein is strategy to significantly improve activity sized at greater nm. The nm, different shapes, negligible Ce 3+ /Ce 4+ ratio can acquire remarkable abilities through electron transfer. This method will make it possible develop nanoceria‐based...
Cartilage tissue is prone to degradation and has little capacity for self-healing due its avascularity. Tissue engineering, which provides artificial scaffolds repair injured tissues, a novel promising strategy cartilage repair. 3D bioprinting offers even greater potential repairing degenerative by simultaneously integrating living cells, biomaterials, biological cues provide customized scaffold. With regard cell selection, mesenchymal stem cells (MSCs) hold great differentiating into...
Chemodynamic therapy (CDT), which induces cell death by decomposing high levels of H2 O2 in tumor cells into highly toxic ·OH, is recognized as a promising antineoplastic approach. However, current CDT approaches are often restricted the controlled and upregulated cellular antioxidant defense. To enhance ·OH-induced damage CDT, covalent organic framework (COF)-based, ferrocene (Fc)- glutathione peroxidase 4 (GPX4) inhibitor-loaded nanodrug, RSL3@COF-Fc (2b), fabricated. The obtained 2b not...
ZIF-8, as an important photoresponsive metal–organic framework (MOF), holds great promise in the field of cancer theranostics owing to its versatile physiochemical properties. However, photocatalytic anticancer application is still restricted because wide bandgap and specific response ultraviolet light. Herein, we developed lanthanide-doped nanoparticles (LDNPs) coated with Fe/Mn bimetal-doped ZIF-8 (LDNPs@Fe/Mn-ZIF-8) for second near-infrared (NIR-II) imaging-guided synergistic...
Abstract Exciton–polaritons (polaritons) resulting from the strong exciton–photon interaction stimulates development of novel low-threshold coherent light sources to circumvent ever-increasing energy demands optical communications 1–3 . Polaritons bound states in continuum (BICs) are promising for Bose–Einstein condensation owing their theoretically infinite quality factors, which provide prolonged lifetimes and benefit polariton accumulations 4–7 However, BIC remains limited cryogenic...
With the increasing applications of metal-based nanoparticles in various commercial products, it is necessary to address their environmental fate and potential toxicity. In this work, we assessed phytotoxicity lanthanum oxide (La2O3) NPs cucumber plants determined its distribution biotransformation roots by TEM EDS, as well STXM NEXAFS. LaCl3 was also studied a reference toxicant. La2O3 were both transformed needle-like LaPO4 nanoclusters intercellular regions roots. vitro experiments...
Significance Nutritional quality and yield are equally important considerations in crop breeding, although they sometimes appear at odds. In this work we made the discovery that these traits linked through regulation by two transcription factors. Mutations affect expression of factors can improve nutritional seed but also reduce kernel hardness. Therefore future corn-breeding programs should silence zein genes directly, not blocking
ABSTRACT This study evaluated the acute toxicity and biokinetics of intravenously administered silver nanoparticles (AgNPs) in mice. Mice were exposed to different dosages AgNPs (7.5, 30 or 120 mg kg −1 ). Toxic effects assessed via general behavior, serum biochemical parameters histopathological observation Biokinetics tissue distribution at a dose both male female Inductively coupled plasma–mass spectrometry (ICP‐MS) was used determine concentrations blood samples collected predetermined...
The broad potential applications of manufactured nanomaterials call for urgent assessment their environmental and biological safety. However, most the previous work focused on cell level performance; little was known about consequences nanomaterial exposure at whole-body organ levels. In present paper, radiotracer technique employed to study pulmonary deposition translocation secondary target organs after ceria nanoparticles (nano-ceria) were intratracheally instilled into Wistar rats. It...
With the increasing utilization of nanomaterials, there is a growing concern for potential environmental and health effects them. To assess risks better knowledge about their fate toxicity in plants are required. In this work, we compared phytotoxicity nanoparticulate Yb(2)O(3), bulk YbCl(3)·6H(2)O to cucumber plants. The distribution biotransformation three materials plant roots were investigated situ by TEM, EDS, as well synchrotron radiation based methods: STXM NEXAFS. decrease biomass...
Abstract Bud dormancy transition is a vital developmental process for perennial plant survival. The precisely regulated by diverse endogenous genetic factors and environmental cues, but the mechanisms are not yet fully understood. Prunus mume an ideal crop bud analysis because of its early spring-flowering characteristics small sequenced genome. Here, we analyzed transcriptome profiles at three endodormancy stages natural flush stage using RNA sequencing combined with phytohormone sugar...
To investigate how the physicochemical properties of nanoparticles (NPs) affect their biological and toxicological effects, we evaluated phytotoxicity CeO2 La2O3 NPs to cucumber (Cucumis sativus) plants tried clarify relation between behaviors. had no at all tested concentrations, while showed significant inhibition on root elongation ( ≥ 2 mg/L), shoot (at 2000 biomass 20 as well induced more reactive oxygen species cell death in roots (2000 mg/L). The different distribution speciation Ce...
CeO<sub>2</sub> nanoparticles showed a higher toxicity to asparagus lettuce in an agar medium than aqueous suspensions.