A5025641446- Surgical site infection prevention
- Breast Implant and Reconstruction
- Breast Cancer Treatment Studies
- Reconstructive Surgery and Microvascular Techniques
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Colorectal Cancer Screening and Detection
- Prenatal Screening and Diagnostics
- Cancer, Lipids, and Metabolism
- Pneumonia and Respiratory Infections
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Orthopedic Infections and Treatments
- Nosocomial Infections in ICU
- Emergency and Acute Care Studies
- Antimicrobial Resistance in Staphylococcus
- Gallbladder and Bile Duct Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Healthcare Policy and Management
- Antifungal resistance and susceptibility
- Neutropenia and Cancer Infections
- Breast Lesions and Carcinomas
- Child and Adolescent Health
Washington University in St. Louis
2016-2025
Lindsay Unified School District
2023
Manhattan Institute for Policy Research
2023
New York Proton Center
2015-2023
Communities In Schools of Orange County
2023
Oregon Medical Research Center
2023
Saint Louis University
2023
Norwegian Womens Public Health Association
2023
Museum of Heilongjiang Province
2021
Office of Infectious Diseases
2017-2021
Factors that lead to metabolic dysregulation are associated with increased risk of early-onset colorectal cancer (CRC diagnosed under age 50). However, the association between syndrome (MetS) and CRC remains unexamined.We conducted a nested case-control study among participants aged 18-64 in IBM MarketScan Commercial Database (2006-2015). Incident was identified using pathologist-coded International Classification Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes, controls...
<h3>Importance</h3> Nonguideline antibiotic prescribing for the treatment of pediatric infections is common, but consequences inappropriate antibiotics are not well described. <h3>Objective</h3> To evaluate comparative safety and health care expenditures vs appropriate oral prescriptions common outpatient infections. <h3>Design, Setting, Participants</h3> This cohort study included children aged 6 months to 17 years diagnosed with a bacterial infection (suppurative otitis media [OM],...
Abstract Background Prompt detection of colorectal cancer (CRC) among individuals younger than age 50 years (early-onset CRC) is a clinical priority because its alarming rise. Methods We conducted matched case-control study 5075 incident early-onset CRC US commercial insurance beneficiaries (113 million adults aged 18-64 years) with 2 or more continuous enrollment (2006-2015) to identify red-flag signs and symptoms between 3 months before the index date 17 prespecified symptoms. assessed...
BackgroundUrinary tract infections (UTI) affect approximately 250 million people annually worldwide. Patients often experience a cycle of antimicrobial treatment and recurrent UTI (rUTI) that is thought to be facilitated by gut reservoir uropathogenic Escherichia coli (UPEC).Methods125 patients with caused an antibiotic-resistant organism (ARO) were enrolled from July 2016 May 2019 in longitudinal, multi-center cohort study. Multivariate statistical models used assess the relationship...
Importance Health care–associated infections (HAIs) are a major cause of morbidity and mortality, but little is known about whether structural factors impacting race rurality associated with HAI subsequent outcomes. Objective To evaluate the association rurality, which proxies for disadvantage, Design, Setting, Participants This cohort study was conducted at 3 US urban suburban hospitals. were adults aged 18 years or older admitted 48 hours longer from January 1, 2017, to August 31, 2020....
Few data are available concerning surgical site infection (SSI) and noninfectious wound complications (NIWCs) after delayed (DR) secondary reconstruction (SR) compared with immediate (IR) procedures in the breast.To compare incidence of SSI NIWCs implant autologous IR, DR, SR breast mastectomy.This retrospective cohort study included women aged 18 to 64 years undergoing mastectomy from January 1, 2004, through December 31, 2011. Data were abstracted a commercial insurer claims database 12...
OBJECTIVE The National Healthcare Safety Network classifies breast operations as clean procedures with an expected 1%–2% surgical site infection (SSI) incidence. We assessed differences in SSI incidence following mastectomy and without immediate reconstruction a large, geographically diverse population. DESIGN Retrospective cohort study PATIENTS Commercially insured women aged 18–64 years ICD-9-CM procedure or CPT-4 codes for from January 1, 2004 through December 31, 2011 METHODS Incident...
There are limited data on risk factors for surgical site infection (SSI) after open or laparoscopic cholecystectomy.A retrospective cohort of commercially insured persons aged 18-64 years was assembled using International Classification Diseases, 9th Revision, Clinical Modification (ICD-9-CM) procedure Current Procedural Terminology, 4th edition codes cholecystectomy from December 31, 2004 to 2010. Complex procedures and patients (eg, cancer, end-stage renal disease) with pre-existing were...
Antipsychotic drugs are well established to alter circulating prolactin levels by blocking dopamine D2 receptors in the pituitary. Prolactin activates many genes important development of breast cancer. Prior studies have found an association with antipsychotic use and risk cancer.The IBM MarketScan Commercial Medicaid Databases were used establish a large, observational cohort women taking antipsychotics compared anticonvulsants or lithium. A new user design was that required 12 months...
We assessed the prevalence of and risk factors for trading sex with a police officer among women recruited from drug courts in St Louis, Missouri.In 2005 to 2008, we into an HIV intervention study, which surveyed participants about multiple sociodemographic, lifestyle, factors. Regression analyses sex, form sexual misconduct (PSM).Of 318 participants, 78 (25%) reported lifetime history PSM. Among who experienced PSM, 96% had on duty, 77% repeated exchanges, 31% rape by officer, 54% were...
Abstract Background Invasive fungal infections are a devastating complication of inflammatory bowel disease (IBD) treatment. We aimed to determine the incidence in IBD patients and examine risk with tumor necrosis factor-alpha inhibitors (anti-TNF) compared corticosteroids. Methods In retrospective cohort study using IBM MarketScan Commercial Database we identified US at least 6 months enrollment from 2006 2018. The primary outcome was composite invasive infections, by ICD-9/10-CM codes plus...
ABSTRACT Purpose Studies using insurance claims data to identify pregnancies are rarely able directly assess the validity of pregnancy/delivery. Inpatient versus outpatient delivery may provide different levels evidence, but more stringent requirements could result in exclusion true pregnancies. We identified codes from inpatient and settings examined possible confirmatory evidence suggesting that a truly occurred. Methods Using US commercial database (2006–2021), we potential by presence...
Objective: To determine the impact of surgical site infections (SSIs) on health care costs following common ambulatory procedures throughout cost distribution. Background: Data SSIs surgery are sparse, particularly variation beyond just mean costs. Methods: We performed a retrospective cohort study persons undergoing cholecystectomy, breast-conserving surgery, anterior cruciate ligament reconstruction, and hernia repair from December 31, 2004 to 2010 using commercial insurer claims data....
OBJECTIVE: To examine the association between state-mandated insurance coverage for infertility treatment in United States and utilization of indication preimplantation genetic testing. METHODS: This was a retrospective cohort study 301,465 vitro fertilization (IVF) cycles reported to Society Assisted Reproductive Technology 2014 2016. Binomial logistic regression performed associations testing use. The neonate’s sex from each patient's first successful cycle used calculate ratios. Sex...
<h3>Objective:</h3> Hereditary hemorrhagic telangiectasia (HHT) is an inherited disease associated with pathogenic variants in TGF-β signaling pathway-related genes, resulting abnormal vascular development various organs. Brain arteriovenous malformations (AVMs) may lead to intracranial hemorrhage, and brain abscess or ischemic stroke result from right left shunting via pulmonary AVMs. We aimed investigate the risk for these severe complications both adult children HHT patients....
Abstract Background Data on the epidemiology of healthcare facility-associated (HCFA) nontuberculous mycobacteria (NTM) are sparse. We performed a multicenter longitudinal cohort study HCFA NTM epidemiology. Methods retrospectively analyzed positive cultures for from 2012 through 2020 within network 10 US academic hospitals and associated clinics. A unique episode was defined as patient's first culture particular species specimen source category (pulmonary vs extrapulmonary). Episodes linked...
Objective To investigate whether operative factors are associated with risk of surgical site infection (SSI) after hernia repair. Design Retrospective cohort study. Patients Commercially insured enrollees aged 6 months-64 years International Classification Diseases, Ninth Revision, Clinical Modification procedure or Current Procedural Terminology , fourth edition, codes for inguinal/femoral, umbilical, and incisional/ventral repair procedures from January 1, 2004, through December 31, 2010....
BACKGROUND The childhood obesity epidemic has grown exponentially and is known to disproportionately affect minority groups. Successful treatment of this complex health issue requires a multidisciplinary approach including metabolic bariatric surgery (MBS) for qualifying pediatric patients. This study examines current national trends in from 2010 2017 using the National Inpatient Sample. METHODS analyzed MBS among patients &lt;19 years old weighted discharge data 2017. primary outcome...
Studies comparing the impact of COVID-19 pandemic on diagnostic microbiology culture yields and antimicrobial resistance proportions in low-to-middle-income high-income countries are lacking. A retrospective study using blood, respiratory, urine data from a community hospital India two hospitals (Hospitals B) St. Louis, MO, USA was performed. We compared proportion cultures positive for selected multi-drug-resistant organisms (MDROs) listed WHO’s priority pathogen list both before (January...
Cryptococcosis is one of the most common life-threatening opportunistic mycoses worldwide. Insidious presentation and slow onset symptoms make it difficult to recognize, complicating diagnostic process. Delays in diagnosis may lead increased mortality. We aim determine frequency missed opportunities for cryptococcosis its effects on mortality.To estimate proportion individuals with a potentially hospitalized patients, we conducted retrospective cohort study using Healthcare Cost Utilization...