- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- CNS Lymphoma Diagnosis and Treatment
- Poxvirus research and outbreaks
- Histone Deacetylase Inhibitors Research
- Listeria monocytogenes in Food Safety
- Pharmaceutical studies and practices
- Neutropenia and Cancer Infections
- Platelet Disorders and Treatments
- Immunodeficiency and Autoimmune Disorders
- Herpesvirus Infections and Treatments
- Sarcoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Parvovirus B19 Infection Studies
- Blood transfusion and management
- Protein Degradation and Inhibitors
- CAR-T cell therapy research
- Cancer Genomics and Diagnostics
- Bacillus and Francisella bacterial research
- Radiomics and Machine Learning in Medical Imaging
- Epigenetics and DNA Methylation
Memorial Sloan Kettering Cancer Center
2021-2023
Thomas Jefferson University Hospital
2022
Presbyterian Hospital
2020
NewYork–Presbyterian Hospital
2020
Cornell University
2020
New York Hospital Queens
2020
Outcomes for children and adolescents with relapsed refractory Hodgkin lymphoma (HL) are poor, ∼50% of patients experiencing a subsequent relapse. The anti-CD30 antibody-drug conjugate brentuximab vedotin improved progression-free survival (PFS) when used as consolidation after autologous stem cell transplantation (ASCT) in adults high-risk relapsed/refractory HL. Data on consolidative therapy ASCT pediatric HL extremely limited, data only 11 reported the literature. We performed...
Myeloid leukemia of Down syndrome (ML-DS) in young children is associated with distinct clinical and biological features typically initiated oncogenic mutations the X-linked megakaryocytic transcription factor GATA1. Here we present a 3-yr-old child DS diagnosed acute myeloid (AML), which lacks typical immunophenotypic molecular characteristics ML-DS, including GATA1 mutations. The leukemic blasts were found to have an MN1-ETV6 gene fusion, high-risk oncofusion not previously described...
Abstract For children with cancer, blood product transfusions are crucial, but can be complicated by transfusion reactions. To prevent these complications, premedication is often given, although not always evidence‐based. Herein, we describe a significant decrease in the use of (72%–28%) at our institution after implementation standardized guidelines, without an increase reactions (3.2% prior vs. 1.5% standardization). Importantly, there were no severe leading to hospitalization or death....
Introduction: Listeria Monocytogenes (L. Monocytogenes) is a gram-positive intracellular bacterium that enters the host by ingestion of contaminated foods. Listeriosis challenging to diagnose, however diagnosis crucial given mortality rate in severe disease. We describe case 26-year-old pregnant female who presented hospital shock secondary L. bacteremia. Description: Hispanic female, 18 weeks pregnant, with fevers, right flank pain, nausea, and vomiting. Vitals on admission were:...