A5030972466- Blood groups and transfusion
- Erythrocyte Function and Pathophysiology
- Blood disorders and treatments
- Blood donation and transfusion practices
- Blood transfusion and management
- Anesthesia and Sedative Agents
- Advanced Radiotherapy Techniques
- Airway Management and Intubation Techniques
- Management of metastatic bone disease
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Hemoglobinopathies and Related Disorders
- Platelet Disorders and Treatments
- Hepatitis B Virus Studies
- Immunodeficiency and Autoimmune Disorders
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Brain Metastases and Treatment
- Hepatitis C virus research
- Cancer Diagnosis and Treatment
- Diabetes Management and Research
- Nausea and vomiting management
- Organ Donation and Transplantation
- Anesthesia and Neurotoxicity Research
- Kidney Stones and Urolithiasis Treatments
Post Graduate Institute of Medical Education and Research
2013-2025
Marymount University
2022
Colorado Permanente Medical Group
2020-2021
Science and Technology Facilities Council
2021
Rutherford Appleton Laboratory
2021
Birkbeck, University of London
2021
Institute of Structural and Molecular Biology
2021
James J. Peters VA Medical Center
2014-2020
Maharishi Markandeshwar University, Mullana
2015-2020
Institute of Medical Sciences
2020
Abstract Background and Objectives Great variations may be observed in the haemoglobin (Hb) content of packed red blood cell (PRBC) units prepared by different methods. This study aimed to assess Hb increment thalassaemia major patients transfused with leucoreduced PRBCs (LPRBCs) two methods: (i) standard (SLPRBCs) (ii) a new method where leucoreduction whole is done first (NLPRBCs). Materials Methods prospective, randomized, controlled trial included 80 adult who were randomized into groups...
Summary We have investigated the incidence of contamination contents glass ampoules used for neuraxial injections, and whether this was reduced by wiping outsides with isopropyl alcohol or using a filter straw. One hundred fentanyl diamorphine routine regional anaesthesia were either wiped not before their aspirated, residual swabbed incubated. None swabs from grew organisms compared nine (18%) non‐wiped (p = 0.004). In second, laboratory study, 100 saline coated Staphylococcus aureus...
ABO incompatibility and other alloantibodies have emerged as a significant cause of hemolytic disease fetus newborn (HDFN), leading to neonatal morbidity mortality. We report three cases severe ABO-HDFN where blood exchange transfusions (ETs) were required in neonates with hyperbilirubinemia. Blood grouping (ABO/RhD) was performed using conventional tube technique. The antibody screen done commercial three-cell panel (Bio-Rad ID-Diacell-I-II-III, Switzerland) by gel Direct antiglobulin test...
This study was performed in 32 ASA I patients undergoing percutaneous nephrolithotripsy under general anaesthesia, using absorption of 1% ethanol as a marker to monitor irrigation fluid absorption. Various parameters were studied and compared, including volume, time, total volume absorbed the rate irrigation. The amount irrigant used vs. time observed. Fluid occurred 78% patients, 28% volumes excess 1 l. mean 696.7 ml. maximum observed when exceeded 10 l, 30 min 200 ml.min −1 , respectively....
Most Veterans Health Administration hospitals do not have radiation oncology (RO) departments on-site. The purpose of this study is to determine the impact on-site RO on referral patterns and timeliness palliative therapy (PRT).A survey was sent medical directors at 149 centers. Questions evaluated frequency for PRT, consults treatment, barriers PRT. Chi-square analysis used evaluate differences between centers that refer outside facilities.Of 108 respondents, 33 (31%) RO. revealed consult...
This study was performed in 32 ASA I patients undergoing percutaneous nephrolithotripsy under general anaesthesia, using absorption of 1% ethanol as a marker to monitor irrigation fluid absorption. Various parameters were studied and compared, including volume, time, total volume absorbed the rate irrigation. The amount irrigant used vs. time observed. Fluid occurred 78% patients, 28% volumes excess 1 l. mean 696.7 ml. maximum observed when exceeded 10 l, 30 min 200 ml.min(-1), respectively....
The percentage of HIV cases attributable to blood transfusion has decreased significantly in the last decade. newer 4(th) generation Enzyme linked immunosorbent assay (ELISA) been shown have increased sensitivity compared 3(rd) ELISA.To estimate seroprevalence among donors using ELISA and compare it with ELISA.This prospective study involved 10,200 donors- 6,800 were voluntary (3400-students 3400-non students) 3400 replacement donors. All units tested as well ELISA. samples found reactive or...
Introduction: Kidd blood group system has a special importance in transfusion medicine as the antibodies to antigens tend go down undetectable levels but show an anamnestic response on exposure through pregnancy or and cause hemolytic reaction, most commonly delayed reaction. Case Report: We report patient who developed alloantibodies 'Kidd a' antigen leading Conclusion: emphasize steps for detecting these precautions be taken once are identified.
Abstract Perforin is a pore-forming protein that facilitates rapid killing of pathogen-infected or cancerous cells by the immune system. released from cytotoxic lymphocytes, together with pro-apoptotic granzymes, to bind plasma membrane target cell where it oligomerises and forms pores. The pores allow granzyme entry, which rapidly triggers apoptotic death cell. Here we present 4 Å resolution cryo-EM structure perforin pore, revealing new inter- intra-molecular interactions stabilising pore....
This prospective, double-blind, randomized study assessed effect of pre-emptive peritonsillar block in 30 ASA-I children, aged 6-12 years, both sexes, scheduled for tonsillectomy. Patients were divided into three groups: those group I received a sham block, whereas blocks with bupivacaine 0.25% given to the children before tonsillectomy (group II) or immediately after surgery had been completed III). Constant pain, pain on swallowing, blood glucose, serum epinephrine and norepinephrine...
Red blood cell alloimmunization to antigens other than D, such as C, c, E, e, and in the Kell, MNS, Duffy group systems, has emerged an important cause of hemolytic disease fetus newborn (HDFN). Antibody screening for these antibodies is not routinely practiced all antenatal patients developing countries, mainly because financial constraints. Here we report a rare case HDFN due dual Rh Kidd system antigens: anti-E anti-Jka. This highlights importance routine regular pregnant women proper...
There is scarce information on the baseline knowledge and practices of nursing officers in relation to administration blood components. We set out evaluate influence training their skills through Kirkpatrick's levels Training Evaluation.This interventional cross sectional study 7 months duration conducted a tertiary care teaching institute involved 200 officers. Hundred were assigned study/intervention group 100 control/ comparison by systematic random sampling. Knowledge was tested...
Mal de meleda (MdM), a rare autosomal recessive genodermatosis is characterized by erythema and hyperkeratosis of the palms soles with sharp demarcation that progress age (progrediens) extend to dorsal aspects hands feet (transgrediens). It has been associated various conditions albeit rarely congenial cataract. Ocular lens skin have same embryological origins. We hereby present this novel case report in association congenital posterior subcapsular cataract which best our knowledge not...