A5032002235- Blood donation and transfusion practices
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Hemoglobinopathies and Related Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Platelet Disorders and Treatments
- Metabolism and Genetic Disorders
- Blood groups and transfusion
- Blood disorders and treatments
- Ion channel regulation and function
- Vaccine Coverage and Hesitancy
- Clinical Laboratory Practices and Quality Control
- COVID-19 epidemiological studies
- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Peripheral Neuropathies and Disorders
- Blood transfusion and management
- Immunodeficiency and Autoimmune Disorders
- S100 Proteins and Annexins
- Immune cells in cancer
- Hemophilia Treatment and Research
- Blood Coagulation and Thrombosis Mechanisms
- Bipolar Disorder and Treatment
- Protein purification and stability
- Metabolomics and Mass Spectrometry Studies
- Cell Adhesion Molecules Research
Post Graduate Institute of Medical Education and Research
2020-2025
BioTelemetry (United States)
2024
Translational Health Science and Technology Institute
2015
Abstract Background and Objectives Great variations may be observed in the haemoglobin (Hb) content of packed red blood cell (PRBC) units prepared by different methods. This study aimed to assess Hb increment thalassaemia major patients transfused with leucoreduced PRBCs (LPRBCs) two methods: (i) standard (SLPRBCs) (ii) a new method where leucoreduction whole is done first (NLPRBCs). Materials Methods prospective, randomized, controlled trial included 80 adult who were randomized into groups...
Abstract BACKGROUND: Buffy coat pooled platelets (BCPP) have recently been licensed for clinical use in India and merits of both the conventional platelet concentrates, i.e., random donor single-donor apheresis (SDAPs). Repeatedly, finding a ABO-matched hemato-oncology patients is challenge. AIM: This study aimed to evaluate feasibility, efficacy, safety, cost-effectiveness BCPP nonrefractory, hemato-oncological comparison SDAP. METHODS: In randomized cross-over design, 93 were assigned...
Background: End-stage renal disease (ESRD) necessitates hemodialysis (HD), a treatment associated with substantial physical and psychological burdens. Anxiety depression are common in ESRD patients can adversely impact their quality of life adherence. This study aimed to evaluate the prevalence anxiety among undergoing chronic HD. Methods: A cross-sectional observational was conducted at SRMS IMS Bareilly involving 100 on Patients completed Hospital Depression Scale (HADS) symptoms...
Neutrophil extracellular traps (NETs) contribute to the pathophysiology of multiple inflammatory and autoimmune diseases. Targeting NETosis pathway has demonstrated significant therapeutic potency in various disease models. Here, we describe a first-in-class monoclonal antibody (CIT-013) with high affinity for citrullinated histones H2A H4, which inhibits reduces tissue NET burden
Neutrophils play an important role in innate immune defense by using several strategies, including the release of neutrophil extracellular traps (NETs) a process referred to as NETosis. However, past two decades, it has become clear that accumulation NETs tissues contributes pathophysiology multiple inflammatory and autoimmune diseases. Therefore, interest development NETosis antagonists risen. Variable non-standardized methods detect analyze were developed concomitantly, each with its own...
Hemoglobin (Hb) estimation in blood donors is conducted using capillary samples on portable hemoglobinometers, representing measurement methods practice. The reference standard a venous sample hematology analyzer, the mentor method or true value. correction involves calculation of secondary adjustment factor (SAF) to mitigate difference between two values. A cross-sectional study enrolled 187 after approval from institute's ethics committee. On each donor, Hb was performed first drop and...
Background: Targeted urinary metabolic profiling of patients with type 2 diabetes mellitus (DM) and diabetic nephropathy (DN) along healthy control was conducted urine being a non-invasive biofluid ideal for the biomarker studies related to kidney disorders. Objective: Other markers risk DN in combination microalbuminuria are needed optimal clinical management. The purpose this study propose new involved pathophysiology DN. Method: Liquid chromatography coupled mass spectrometry (LC-MS)...
Isaacs syndrome is a disease characterized by nerve hyperexcitability and pseudomyotonia treated with immunomodulatory symptomatic therapy approaches. Here, we report case of anti-(leucine-rich glioma-inactivated 1) antibody-positive patient diagnosed as accomplished nearly complete response to only four sessions therapeutic plasma exchange (TPE). Our experience suggests that TPE along other agents may be beneficial well-tolerated approach in syndrome.
The blood collection agencies (BCAs) employ two major logistical modes of conduct for outdoor collection. First, the agency walks to donor's preferred location routine donation drives. Second, drive is conducted using a heavy-duty vehicle having all facilities in it - Blood Donation on Wheels hereinafter referred as mobile (MBD). study aimed review role MBDs during coronavirus disease 2019 (COVID-19) pandemic. This was retrospective analysis data concerning at drives such number drives,...