A5101928719- Alzheimer's disease research and treatments
- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Cholinesterase and Neurodegenerative Diseases
- Tea Polyphenols and Effects
- Plant responses to water stress
- Computational Drug Discovery Methods
- Plant Gene Expression Analysis
- Gut microbiota and health
- Genetic and phenotypic traits in livestock
- Livestock and Poultry Management
- Neurological Disorders and Treatments
- Biopolymer Synthesis and Applications
- Genomics, phytochemicals, and oxidative stress
- Optimism, Hope, and Well-being
- Sperm and Testicular Function
- Neurological diseases and metabolism
- Family Support in Illness
- Resilience and Mental Health
- Advances in Cucurbitaceae Research
- Plant Pathogenic Bacteria Studies
- Cholesterol and Lipid Metabolism
- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Southern Medical University
2013-2024
Zhujiang Hospital
2020-2024
Ministry of Education of the People's Republic of China
2024
Anhui Agricultural University
2017-2024
Chinese People's Liberation Army
2022
State Key Laboratory of Kidney Diseases
2022
Chengdu University of Traditional Chinese Medicine
2022
Chinese PLA General Hospital
2022
Hainan University
2022
Zhuhai People's Hospital
2019
Abstract The transformation and gene editing of the woody species kiwifruit are difficult time-consuming. fast marker-free genetic modification system for has not been developed yet. Here, we establish a rapid efficient mediated by Agrobacterium rhizogenes kiwifruit. Moreover, removing-root-tip method was to significantly increase regeneration efficiency transgenic hairy roots. Through A. -mediated CRISPR/Cas9 editing, efficiencies CEN4 AeCBL3 achieved 55 50%, respectively. And several...
The ice nucleation protein (INP) of Pseudomonas syringae has gained scientific interest not only because its pathogenicity foliar necroses but also for wide range potential applications, such as in snow making, frozen food preparation, and surface-display system development.However, studies on the transport activity INP remain lacking.In present study, a newly identified INP-gene variant, inaQ, from P. MB03 strain was cloned.Its structural domains, signal sequences, hydrophilicity or...
Fruit ripening is associated with the degreening process (loss of chlorophyll) that occurs in most fruit species. Kiwifruit one special species whose fruits may maintain green flesh by accumulating a large amount chlorophyll even after ripening. However, little known about genetic variations related to process. Here, graph-based kiwifruit pangenome analyzing 14 chromosome-scale haplotype-resolved genome assemblies from seven representative cultivars or lines Actinidia chinensis built. A...
Gibberellins (GAs), a class of diterpenoid phytohormones, play key role in regulating diverse processes throughout the life cycle plants. Bioactive GA levels are rapidly regulated by Gibberellin-dioxygenases (GAox), which involved biosynthesis and deactivation gibberellin. In this manuscript, comprehensive genome-wide analysis was carried out to find all GAox Camellia sinensis. For first time tea plant, 14 CsGAox genes, containing two domains, DIOX_N (PF14226) 2OG-FeII_Oxy, were identified...
Graph clustering is an unsupervised machine learning method that partitions the nodes in a graph into different groups. Despite achieving significant progress exploiting both attributed and structured data information, methods often face practical challenges related to isolation. Moreover, absence of collaborative for limits their effectiveness. In this paper, we propose framework graphs, supporting over vertically partitioned with participants holding distinct features same data. Our...
Abstract Background Clear cell renal carcinoma (ccRCC) remains a challenging cancer type due to its resistance standard treatments. Immunogenic death (ICD) has the potential activate anti-tumor immunity, presenting promising avenue for ccRCC therapies. Methods We analyzed data from GSE29609, TCGA-KIRC, and GSE159115 identify ICD-related prognostic genes in ccRCC. By applying consensus clustering, patients were categorized based on ICD modification patterns, an signature (ICDS) model was...
Geniposide, as a type of iridoid glycoside, has antioxidative capacity. However, the mechanism underlying effect geniposide in cadmium (Cd)‑induced osteoblast injury remains only partly elucidated. In present study, Cell Counting Kit‑8 (CCK‑8) was used to determine MC‑3T3‑E1 cell viability. Flow cytometry rate apoptosis and levels reactive oxygen species (ROS). Oxidative stress‑related factors were assessed using enzyme‑linked immunosorbent method (ELISA). Quantitative real‑time polymerase...
Tea-derived polyphenols have anticancer and antioxidant properties, they can regulate oxidative stress. This study was designed to quantify both the toxic effects of fine particulate matter with aerodynamic diameter less than 2.5 μm (PM2.5) determine whether tea could provide a protective effect against PM2.5 toxicity on human alveolar epithelial A549 cells in vitro. Cytotoxic were measured by means cell viability, expression caspase-3, bax/bcl-2, C/EBP-homologous protein (CHOP), generation...
Emerging evidence has indicated a link between the gut microbiota and acute lymphoblastic leukaemia (ALL). However, changes in during chemotherapy predictive value of baseline infectious complication remain largely unknown.
Background Oral microbes mediate the production of nitric oxide (NO) through denitrification pathway. This study aimed to investigate association between oral microbial nitrate metabolism and prognosis in acute ischemic stroke (AIS) patients.
Glucosinolates are secondary metabolites derived from amino acids. Upon hydrolysis by myrosinases, they produce a variety of biologically active compounds. In this study, the glucosinolate–myrosinase system was characterized in Arabidopsis suspension cells. A total seven glucosinolates were identified and myrosinase activity determined. Plant cells have been used as model systems many areas study. To investigate whether works similarly to that planta, 10-day-old seedling hypocotyls for...
Kiwifruit (Actinidia chinensis) is commonly covered by fruit hairs (trichomes) that affect kiwifruit popularity in the commercial market. However, it remains largely unknown which gene mediates trichome development kiwifruit. In this study, we analyzed two species, A. eriantha (Ae) with long, straight, and bushy trichomes latifolia (Al) short, distorted, spare trichomes, second- third-generation RNA sequencing. Transcriptomic analysis indicated expression of NAP1 gene, a positive regulator...