- Data Quality and Management
- Additive Manufacturing Materials and Processes
- Privacy-Preserving Technologies in Data
- Additive Manufacturing and 3D Printing Technologies
- Intermetallics and Advanced Alloy Properties
- Access Control and Trust
- Context-Aware Activity Recognition Systems
- MXene and MAX Phase Materials
- Advanced ceramic materials synthesis
- High Entropy Alloys Studies
- IoT and Edge/Fog Computing
- Titanium Alloys Microstructure and Properties
- Service-Oriented Architecture and Web Services
- Cryptography and Data Security
- Aluminum Alloy Microstructure Properties
- Cloud Data Security Solutions
- Welding Techniques and Residual Stresses
- Library Science and Information Systems
- Solidification and crystal growth phenomena
- Robotics and Automated Systems
- Data Management and Algorithms
- Ethics in Clinical Research
- Powder Metallurgy Techniques and Materials
- Metallurgy and Material Forming
- Metal Forming Simulation Techniques
Neue Materialien Fürth GmbH
2011-2023
Klinikum Fürth
2011-2023
Technische Universität Dresden
2013-2022
National Center for Tumor Diseases
2022
Friedrich-Alexander-Universität Erlangen-Nürnberg
2022
Institute for New Media
2022
University Hospital Carl Gustav Carus
2022
Leipzig University
1976-2021
Lightweight intermetallic γ-TiAl based alloys are innovative high-temperature structural materials. So far, these in use as turbine blades or turbocharger wheels advanced aerospace and automotive engines, where they produced by means of investment casting well wrought processing, e.g. hot-forging. Through the development powder-based additive manufacturing processes within last decade, a real paradigm shift for future component production their design materials properties was created. While...
•14.3% of patients with rare cancers and/or younger age onset carried a PGV.•PGVs were highly enriched in certain cancer entities, i.e. wild-type GISTs and leiomyosarcomas.•High PGV yields ATM, BRCA2, or PALB2 entities indicated potentially novel genotype–phenotype associations.•75% PGVs predisposition genes newly diagnosed due to study participation (118/157).•45% all supported molecularly informed therapeutic recommendations benefit 40% patients. BackgroundGermline variant evaluation...
Knowledge concerning powder degradation during additive manufacturing (AM) processing is essential to improve the reusability of in AM and hence maximize feedstock reuse economy process. AlSi10Mg Concept Laser XLINE 2000R machine over total period 30 months was analyzed order understand extent mechanism affecting aging. Thereby, detailed analysis morphology, microstructure surface chemistry performed by SEM, TEM XPS. The results show an increase volume fraction heavily oxidized spatter...
Laser-based powder bed fusion (PBF-LB/M) is a well-established additive manufacturing (AM) process capable of producing high quality parts with excellent mechanical properties. Industrial applications additively manufactured require the usage fresh which makes expensive, especially in case AM machines enlarged build envelopes. Processing long-term reused fits to economic yields drawback increased porosity and incorporated oxides. In this study, detailed analysis components made virgin...
With electron beam powder bed fusion (PBF-EB), an additive manufacturing (AM) technique, complex-shaped components with excellent properties from high-temperature materials can be manufactured. The latest research on the PBF-EB technique reveals possibility of establishing different microstructures and differing mechanical inside a component made titanium aluminides (TiAl). In detail, two well-adjusted process parameter sets lead to varying melt pool characteristics significant change in...
The development of process parameters for electron beam powder bed fusion (PBF-EB) is usually made with simple geometries and uniform scan lengths. transfer to complex parts various lengths can be achieved by adapting such as power speed. Under ideal conditions, this adaption results in a constant energy input into the despite local length. However, numerous PBF-EB machines show deviations from situation because diameter subject significant changes if changed. This study aims demonstrate...
Electron Beam Powder Bed Fusion (PBF-EB) is an Additive Manufacturing (AM) method that utilizes electron beam to melt and consolidate metal powder. The beam, combined with a backscattered detector, enables advanced process monitoring, termed Optical Imaging (ELO). ELO already known provide great topographical information, but its capabilities regarding material contrast are less studied. In this article the extents of using investigated, focusing mainly on identifying powder contamination....
In this work, the process of developing a flexible and semantic middleware (SeMiWa) for cyber-physical systems is presented. The proposed system focus challenge controllability in heterogeneous wireless infrastructure smart home environment. With model-based approach, it possible to react on rapidly changing environment therefore, assist user seamless integrate its devices, e.g. new sensors. To solve problem interoperability, we use annotated XMPP messages as transmission format, annotator...
This paper presents the results of an investigation on interrelationship between thermophysical properties, processing conditions and primary dendrite arm spacing for a nickel-base superalloy. The research was realized CMSX-4, directionally solidified in Bridgman furnace. For systematic, fast cost-efficient numerical finite element models were applied. model, composed material data, geometric data boundary conditions, calibrated experimentally validated. Microstructural parameters castings...
Abstract Background Data analysis for biomedical research often requires a record linkage step to identify records from multiple data sources referring the same person. Due lack of unique personal identifiers across these sources, relies on similarity such as first and last names or birth dates. However, exchange identifying with third party, is case in linkage, generally subject strict privacy requirements. This problem addressed by privacy-preserving (PPRL) pseudonymization services....
Privacy-preserving record linkage (PPRL) is increasingly demanded in real-world applications, e.g., the health-care domain, to combine person-related data for analysis while preserving privacy of individuals. However, adoption PPRL hampered by absence easy-to-use and powerful tools covering entire process. We therefore demonstrate Primat, a flexible scalable tool that enables definition application tailored workflows as well comparative evaluation different methods. introduce main...
The dual microstructure concept for gamma titanium aluminides (γ-TiAl) processed via electron beam–powder bed fusion (PBF-EB) provides a huge potential more efficient jet turbine engines. While the is feasible and mechanical properties are promising, there still some challenges. For an industrial application, heat treatment window has to match conditions in furnaces. This study shows how required can be achieved advanced PBF-EB technology. Through using beam with 150 kV acceleration voltage,...
In this work, we combine the field of cloud computing with assisted living to utilize an improved activity classification. The proposed system addresses challenge enabling heterogeneous, cloud-based sensors in small home environments. With a semantic and model-based approach, seamlessly integrate Web services as virtual and, therefore, increasing accuracy human classifiers. We solve most important compelling issue interoperability, by using generated wrapper classes semantically unify all...