A5048014962- Pulmonary Hypertension Research and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- COVID-19 Clinical Research Studies
- Cardiac tumors and thrombi
- Cardiovascular Issues in Pregnancy
- Cardiac Arrhythmias and Treatments
- Mechanical Circulatory Support Devices
- COVID-19 and healthcare impacts
- Cardiac electrophysiology and arrhythmias
- Infective Endocarditis Diagnosis and Management
- Medical Imaging and Pathology Studies
- Pericarditis and Cardiac Tamponade
- Cardiomyopathy and Myosin Studies
- Vascular Anomalies and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Takotsubo Cardiomyopathy and Associated Phenomena
- Ultrasound in Clinical Applications
- Acute Ischemic Stroke Management
University of Lisbon
2015-2024
Hospital de Santa Maria
2015-2024
Lusíada University of Lisbon
2024
Centro Hospitalar Lisboa Norte
2020-2024
CUF Porto Hospital
2023
Hospital Universitário de Santa Maria
2021
Institute of Cardiology
2021
Ospedale Policlinico San Martino
2018
Assistance Publique – Hôpitaux de Paris
2014-2017
Inserm
2015-2017
We present the case of a 60-year-old woman with Brugada syndrome, permanent type 1 electrocardiographic pattern, who had previously received an implantable cardioverter-defibrillator. She suffered frequent syncopal episodes and multiple appropriate shocks (around five per month) due to polymorphic ventricular tachycardia/ventricular fibrillation, refractory quinidine therapy. Combined epicardial endocardial electroanatomical mapping was performed view substrate ablation. An area abnormal...
Ruling out pulmonary embolism (PE) through a combination of clinical assessment and D-dimer level can potentially avoid excessive use computed tomography angiography (CTPA). We aimed to compare the diagnostic accuracy standard approach based on Wells Geneva scores combined with cut-off (500 ng/ml), three alternative strategies (age-adjusted YEARS PEGeD algorithms) in patients admitted emergency department (ED) suspected PE.
Abstract Aims We hypothesize that miRs are key players in the dynamics of hypertrophy phenotype aortic stenosis (AS) patients. In our study, we aimed to identify transcriptional patterns (protein-coding transcripts and miRs) from myocardial sample biopsies could be associated with absence left ventricular (LV) mass regression after valve replacement (AVR) patients severe AS LV hypertrophy. Methods results prospectively included 40 AS, hypertrophy, preserved ejection fraction undergoing AVR....
See also: Commentaire de travail M. Fracchia et al., pp. 448Endoscopy 2010; 42(06): 522-522DOI: 10.1055/s-0031-1291862
É apresentado o caso de uma doente 60 anos com síndrome Brugada, padrão tipo 1 permanente, portadora cardioversor‐desfibrilhador, episódios frequentes síncope por taquicardia ventricular polimórfica/fibrilhação (cerca cinco mês), refratários à terapêutica quinidina e múltiplos choques apropriados. Foi efetuado mapeamento eletroanatómico endocárdico epicárdico do ventrículo direito, em ritmo sinusal, confirmando‐se a presença área epicárdica na região anterior da câmara saída direita...
Pulmonary hypertension (PH) covers a group of conditions characterized by an increase in pulmonary vascular resistance leading to right ventricular failure. Risk stratification is crucial for adequate prognostic and therapeutic assessment. However, the accuracy conventional parameters limited, especially biomarkers. To determine value new biomarkers their combination multi-biomarker approach predict outcome patients with PH. In this prospective cohort study, PH underwent clinical,...
Pulmonary hypertension (PH) covers a group of conditions characterized by an increase in pulmonary vascular resistance leading to right ventricular failure. Risk stratification is crucial for adequate prognostic and therapeutic assessment. However, the accuracy conventional parameters limited, especially biomarkers.To determine value new biomarkers their combination multi-biomarker approach predict outcome patients with PH.In this prospective cohort study, PH underwent clinical,...
A polineuropatia amiloidótica familiar (PAF) é uma doença rara devida à deposição sistémica de variantes amiloidogénicas da proteína transtirretina (TTR). TTR‐V30M consiste na substituição valina pela metionina posição 30 e atinge especialmente o sistema nervoso periférico autonómico. As manifestações cardiovasculares são muito comuns devem‐se desnervação autonómica amiloide no coração. simpática cardíaca, detetada por cintigrafia com metaiodobenzilguanidina (MIBG) marcada I123, um...
Familial amyloid polyneuropathy (FAP) is a rare disease caused by systemic deposition of amyloidogenic variants the transthyretin (TTR) protein. The TTR-V30M mutation substitution valine methionine at position 30 and mainly affects peripheral autonomic nervous systems. Cardiovascular manifestations are common due to denervation in heart. Cardiac sympathetic detected iodine-123 labeled metaiodobenzylguanidine (MIBG) an important prognostic marker TTR-V30 M FAP. Liver transplantation, widely...
Abstract Aims Changes in echocardiographic parameters and biomarkers of cardiac venous pressures or estimated plasma volume during hospitalization associated with decongestive treatments acute heart failure (AHF) patients either preserved left ventricular ejection fraction (LVEF) (HFPEF) reduced LVEF (HFREF) are poorly assessed. Methods results From the metabolic road to diastolic failure: (MEDIA‐DHF) study, 111 were included this substudy: 77 AHF (43 HFPEF 34 HFREF) non‐cardiac dyspnea...
Introduction: The 6-minute walk test (6 MWT) distance is frequently used in the prediction of pulmonary hypertension (PH) prognosis. However, potential surrogates this measure have not been established. We aim to describe clinical, echocardiographic, and laboratorial criteria determining 6 MWT patients with PH. Methods: In 22 consecutive PH patients, functional capacity was evaluated by compared levels neurohormonal activation biomarkers echocardiographic parameters for right ventricular...
A persistent left superior vena cava (PLSVC) was present in a 74 year-old man with dilated cardiomyopathy undergoing implantation of cardiac resynchronization therapy device defibrillator (CRT-D). dual-coil active-fixation lead positioned the right ventricular apex, followed by SonRO active fixation atrial free wall. The coronary sinus advanced into postero-lateral vein (Panel A). All three leads were implanted through PLSVC. acute thresholds normal. chest X-ray performed to confirm...
A tromboendarterectomia pulmonar (TP) é um procedimento potencialmente curativo em doentes com hipertensão (HP) tromboembólica crónica (TEC). O objetivo deste trabalho reportar a experiência inicial de centro português tratamento HP submetidos TP num referência cirúrgico internacional. Estudo observacional prospetivo consecutivos diagnóstico HPTEC seguidos nacional e internacional entre outubro 2015 março 2019. Parâmetros clínicos, funcionais, laboratoriais, imagiológicos hemodinâmicos foram...
Pulmonary endarterectomy (PEA) is a potentially curative procedure in patients with chronic thromboembolic pulmonary hypertension (CTEPH). This study reports the initial experience of Portuguese PH center undergoing PEA at an international surgical reference center. Prospective observational consecutive CTEPH followed national center, who underwent between October 2015 and March 2019. Clinical, functional, laboratory, imaging hemodynamic parameters were obtained 12 months preceding surgery...