A5100362968- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Vibrio bacteria research studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Protein Degradation and Inhibitors
- Beetle Biology and Toxicology Studies
- Angiogenesis and VEGF in Cancer
- Neurofibromatosis and Schwannoma Cases
- RNA Interference and Gene Delivery
- Peptidase Inhibition and Analysis
- Advanced biosensing and bioanalysis techniques
- Immune Response and Inflammation
- Cancer Mechanisms and Therapy
- Aquaculture disease management and microbiota
Songjiang District Central Hospital
2019-2024
First Affiliated Hospital of Zhengzhou University
2022-2023
City Of Hope National Medical Center
2019
Cancer Genetics (United States)
2019
Harbin Medical University
2018
Second Affiliated Hospital of Harbin Medical University
2018
Osteosarcoma is the most common bone tumor and characterizes a high metastatic potential. In osteosarcoma, angiogenesis reported to be closely associated with metastasis. Understanding underlying mechanisms accordingly developing therapeutic strategies are urgently desired. Antimalarial agent, artemisinin, has been inhibit angiogenesis. However, we still knew little about effects of artemisinin on its potential molecular in human osteosarcoma. this study, found that could induce both...
Abstract Nucleoside analogs represent the backbone of several distinct chemotherapy regimens for acute myeloid leukemia (AML) and combination with tyrosine kinase inhibitors has improved survival AML patients, including those harboring poor‐risk FLT3‐ITD mutation. Although these compounds are effective in killing proliferating blasts, they lack activity against quiescent stem cells (LSCs), which contributes to initial treatment refractoriness or subsequent disease relapse. The reagent...
In Brief Study Design. Retrospective analysis. Objective. To determine the prognostic indicators in patients with solitary plasmacytoma of bone (SPB) spine. Summary Background Data. Population-level estimates for prognosis among SPB spine are still lacking. Sociodemographic and clinical predictors outcome have not been well characterized. Methods. The Surveillance, Epidemiology, End Results Registry was used to identify all from 1995 through 2014. Associated population data were annual...
Risk stratification for normal karyotype acute myeloid leukemia (NK-AML) remains unsatisfactory, which is reflected by the high incidence of relapse. This study aimed to evaluate role gene mutations and clinical characterization in predicting relapse patients with NK-AML. A prognostic system NK-AML was constructed. panel explored using next-generation sequencing. nomogram algorithm used build a genomic mutation signature (GMS) (GMSN) model that combines GMS, measurable residual disease,...
Background: Risk stratification for normal karyotype acute myeloid leukemia (NK-AML) remains unsatisfactory owing to the high incidence of relapse.Methods: A prognostic system NK-AML was estimated based on gene mutations, measurable residual disease (MRD), and clinical characteristics. panel mutations explored using next-generation sequencing. The least absolute shrinkage selection operator, nomogram algorithm were used build a genomic mutation signature (GMS) (GMSN) model combining GMS,...