A5065201086- Hearing, Cochlea, Tinnitus, Genetics
- Hearing Loss and Rehabilitation
- Vestibular and auditory disorders
- Ear Surgery and Otitis Media
- Electron Spin Resonance Studies
- Hearing Impairment and Communication
- Noise Effects and Management
- Chemotherapy-induced organ toxicity mitigation
- Glaucoma and retinal disorders
- Neuroscience and Music Perception
- Neuroblastoma Research and Treatments
- Ophthalmology and Eye Disorders
- Multisensory perception and integration
- Streptococcal Infections and Treatments
- Language Development and Disorders
- Injury Epidemiology and Prevention
- Neuroscience of respiration and sleep
- Cancer therapeutics and mechanisms
- Ginseng Biological Effects and Applications
- Head and Neck Anomalies
- Erythropoietin and Anemia Treatment
- Brain Metastases and Treatment
- Migraine and Headache Studies
- Botulinum Toxin and Related Neurological Disorders
- Nasal Surgery and Airway Studies
Dokuz Eylül University
2015-2024
Dokuz Eylül Üniversitesi Hastanesi
2021-2023
Boğaziçi University
2020
Institute of Physiology and Pathology of Hearing
2020
Royal Prince Alfred Hospital
2020
The University of Sydney
2020
State Hospital
2014
Abstract Objectives Cisplatin is an anti‐neoplastic agent treatment with which causes many side effects including ototoxicity. The aim of this study was to investigate whether acetyl‐ l ‐carnitine would have protective on cisplatin‐induced ototoxicity in vitro, and if present, reveal roles apoptotic gene expressions pro‐inflammatory cytokines. Materials methods House Ear Institute‐Organ Corti 1 cell line used for study. Apoptotic genes were evaluated apoptosis PCR array cytokine levels...
Objectives: The aim of this study is to investigate the attitudes displayed by students without disabilities studying in Dokuz Eylul University towards people with disabilities, and their perceptions observations regarding types discrimination faced disabilities.Methods: was conducted 1766 attending faculty education health. data were collected using 'Attitudes Towards Disabled Persons' (ATDP) Scale a questionnaire prepared 'discrimination based on disability'.Results: Of students, 62.6%...
To evaluate the protective effects of acetyl L-carnitine (ALCAR) on cisplatin-induced nephrotoxicity in rats, and to gain insights into possible mechanisms ALCAR against nephrotoxicity.Twenty-eight Wistar rats were divided four groups. Group 1 was administered saline only, group 2 ALCAR, 3 cisplatin, 4 prior cisplatin. Rats sacrificed after 72 h cisplatin/saline infusion. Serum creatinine glomerular filtration rate values obtained, kidney samples examined by light electron microscopy....
Our objectives were to study effects of orally administered resveratrol (RV) against cisplatin (CDDP) ototoxicity in different doses and investigate ultrastructural changes the cochlea brainstem.In vivo using an animal model.Thirty-two male Wistar albino rats divided into six groups. Baseline distortion product otoacoustic emissions (DPOAEs) auditory brainstem response (ABR) measurements made. In groups I, II, III, only saline, RV, CDDP given, respectively. Group IV, V, VI animals 10...
Meniere's disease is an otological characterized by various symptoms that include episodic peripheral vertigo, sensorineural hearing loss, tinnitus, and aural fullness, all of which deteriorate the maintenance daily activities. We aimed to investigate cognitive function in patients compare their results those healthy controls. Eighteen diagnosed with definite without any psychiatric, neurological or comorbidity, 30 controls normal functions were included study. General status, attention,...
The aim of this study was to investigate and compare the auditory findings in vestibular migraine (VM) patients without a history vertigo.This conducted on 44 diagnosed with definite VM 31 who were followed treated between January 2011 February 2015. Also, 52 healthy subjects included as control group. All participants underwent detailed otorhinolaryngological examination by audiological evaluation, including pure tone audiometry, speech reception threshold, recognition score, acoustic...
MATERIALS and METHODS: The most frequently used Turkish monosyllabic words were selected from the corpus. Thirty-six young adults with normal hearing divided into two groups asked to listen word pool; given twice at six different intensity levels. least known identified eliminated in order provide homogeneity. Three lists, each composed of 50 phonemically balanced words, developed be tests. These lists according phonemic balance criteria. RESULTS: No statistically significant difference was...
The aim of this study was to analyze the location and size perforation in cases with tympanic membrane perforation, its relation manubrium mallei middle ear volume, investigate how these are correlated severity frequencies conductive hearing loss.This prospectively designed included patients who presented Department Otorhinolaryngology at Dokuz Eylül University loss or tinnitus complaints period from June 2014 through 2017 were identified have their otoscopic examination. Patients underwent...
Tympanometry is a non-invasive, quick, and inexpensive method for examining the middle-ear function. Its limited value in differentiating otosclerotic from normal middle ears caused researchers to develop new methods evaluation of ears. Resonant frequency had been found be higher than normals. We conducted multiple-frequency tympanometry measurements 25 surgically confirmed 100 Mean resonant group was 1190 Hz mean control 934.6 (p<0.001). With cut off 1025 (based on 95% confidence interval),...
<i>Introduction:</i> Cisplatin (CDDP) is an effective and widely used chemotherapeutic agent for pediatric tumors, ototoxicity one of the dose-limiting side effects. <i>Objective:</i> It was aim our study to investigate effect acetyl <i>L</i>-carnitine (ALCAR) on experimental CDDP by audiologic tests, histomorphologic, immunohistochemical ultrastructural examinations apoptotic pathways. <i>Materials Methods:</i> Wistar albino rats (n = 28) were...
The aim of our study was to investigate the effects Korean Red Ginseng (KRG) on cisplatin (CDDP) ototoxicity in vivo and vitro.The first part conducted House Ear Institute-Organ Corti 1 (HEI-OC1) cell line. Cells were treated with CDDP, KRG, their combination for 24 h. Cell viability, apoptosis, expression 84 apoptosis-related genes analyzed. In second study, 30 Wistar albino rats divided into five groups. Baseline distortion product otoacoustic emissions (DPOAEs) auditory brainstem response...
Hearing loss significantly affects communication, social interactions, and the overall quality of life. The bone-anchored hearing aid (BAHA) is an implantable system that bypasses outer middle ear to directly stimulate cochlea through bone conduction. This study aimed compare performance subjective auditory ability improvements between transcutaneous percutaneous BAHA devices using audiological assessments Speech, Spatial Qualities Scale. cross-sectional prospective included 29 participants...
Neonatal hyperbilirubinaemia is a common cause of early onset sensorineural hearing loss. There no exact method to detect the extent neurotoxicity bilirubin. On other hand, auditory pathway known be one most sensitive parts central nervous system (CNS) this toxic agent. This prospective follow-up study was performed evaluate and compare factors related neonates with severe an age-matched control group. Both these groups were tested using brainstem response (ABR) as well evoked otoacoustic...
Abstract Background: The objective of this study was to investigate the incidence hearing loss in neonates and evaluate feasibility a two‐stage Transient Evoked Otoacoustic Emission (TEOAE) screening test. Maternal concerns about were also studied. Methods: Neonatal intensive care patients well babies screened using TEOAE test, which followed by an Auditory Brainstem Response (ABR) test for those who failed first twice. Results: In total, 711 screened. At end two tests, cumulative pass rate...
Wide-band tympanometry (WBT) was introduced as a beneficial diagnostic test for Ménière's disease (MD) almost 15 years ago. However, an acute episode of MD has not been evaluated by using WBT yet.To investigate findings in patients with during attacks.Thirty definite unilateral low-tone sensorineural hearing loss and aural fullness, thirty age- sex-matched control subjects were enrolled prospectively tertiary referral center. Ears divided into three groups follows: (1) affected ears...