A5071211589- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Gastroesophageal reflux and treatments
- Reproductive biology and impacts on aquatic species
- Animal Behavior and Reproduction
- Eosinophilic Esophagitis
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Neuroendocrine regulation and behavior
- Colorectal Cancer Screening and Detection
- Marine and fisheries research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Fish Ecology and Management Studies
- Rabies epidemiology and control
- Gastrointestinal disorders and treatments
- Veterinary Equine Medical Research
- Physiological and biochemical adaptations
- Insect and Pesticide Research
- Meat and Animal Product Quality
- Aquaculture Nutrition and Growth
- Sperm and Testicular Function
- Vector-Borne Animal Diseases
- Dermatology and Skin Diseases
- Olfactory and Sensory Function Studies
- Polyamine Metabolism and Applications
- Human-Animal Interaction Studies
Okayama University of Science
2019-2025
Tokyo Medical University Hospital
2020-2024
Tokyo Medical University
2020-2024
IRYO Sosei University
2009-2021
Ichinomiya Municipal City Hospital
2018-2021
National Center for Global Health and Medicine
2020
Bentham Science Publishers (United Arab Emirates)
2014
Bentham Science Publishers (China)
2014
Kyoto University
2010
The University of Tokyo
1998-2007
Background & aimsMedication is a major determinant of human gut microbiome structure, and its overuse increases the risks morbidity mortality. However, effects certain commonly prescribed drugs multiple medications on are still underinvestigated.MethodsWe performed shotgun metagenomic analysis fecal samples from 4198 individuals in Japanese 4D (Disease, Drug, Diet, Daily life) project. A total 759 were profiled, other metadata, such as anthropometrics, lifestyles, diets, physical activities,...
We examined the differences in serum iron (Fe) concentrations and related variables between summer winter Noma horses. Blood samples were collected from 37 clinically normal horses seven consecutive times: September 2018, February 2019, October 2020, 2021, 2022. Serum Fe ranged 74 μg/dl to 316 with a median of 176 μg/dl. The lower stallions compared mares geldings, tended be low at 10-14 years age, then increased age. repeatedly high winter. Total iron-binding capacity (TIBC), Fe-saturation...
A new image-enhanced endoscopy method called texture and colour enhancement imaging (TXI) enhances brightness, surface irregularities, subtle changes in endoscopic images. However, it is unclear whether TXI narrow-band (NBI) with third-generation high-vision transnasal ultrathin are advantageous over white-light (WLI) for detecting atrophy, intestinal metaplasia, map-like redness gastric cancer. We investigated to compare the efficacy evaluation of gastritis between NBI clarified compared...
To test the hypothesis that primer pheromone responsible for inducing “male effect” is produced in sebaceous gland androgen dependently, we examined correlation between morphological changes of glands and activity skin samples taken from castrated goats had been treated with testosterone. Five were implanted s.c. testosterone capsules to maintain physiological levels plasma four weeks. Skin obtained head region on Day 0 (the day implant), 7, 14, 28 removal), 36, 42, 56. Matched blood also...
Plasticity in sex differentiation is known to be common teleost fishes. Anemonefishes are protandrous; females the largest and dominant members of social groups, displaying frequent aggressive behavior towards other groups. The second-ranked individuals become males others remain as non-reproductive individuals. Here we examine influence interaction in-group on false clown anemonefish, Amphiprion ocellaris, under laboratory conditions. Three juvenile anemonefish were kept a tank for 180 days...
Anemonefish, Amphiprion spp., are socially controlled, protandrous sex changers with a monogamous mating system. Under certain conditions, sexually immature anemonefish ambisexual gonads differentiate directly into males or females. Formation and maintenance of social rank in group considered key requirements for the induction change differentiation. Generally, each animal living experiences different level stress accordance its rank, we hypothesize that situation individual influences...
The Noma horse is a Japanese breed from the region of Imabari City, Ehime Prefecture. To obtain reference hematological and biochemical values, we performed examinations in 39 clinically healthy, mature horses managed at public ranch. Hematological results were close to normal ranges U.S.A. erythrocyte parameters hepatobiliary enzyme levels Kiso lower than those racehorses. showed higher triglyceride concentrations creatinine concentration compared with horses. These data represent first...
Backgrounds: The etiology of gastroesophageal reflux disease (GERD) including esophagitis and non-erosive is multifactorial a recent meta-analysis showed no association between the development GERD Helicobacter pylori eradication in both Western East-Asian populations. However, problem remains that various inclusion criteria are used these studies, which hinders meta-analysis. With focus on with endoscopic mucosal injury, we meta-analysed to evaluate symptoms using clearly defined set...
This study aimed to evaluate the influence of seasons and sex on body size hematological biochemistry parameters Noma horses, a native Japanese breed. Body was larger in winter than summer. Laboratory testing variables, including erythrocytic urea nitrogen, total cholesterol, creatinine kinase levels, were higher winter, while eosinophil count These seasonal differences may be related increased energy consumption horses due heat stress. The counts have been dermatitis observed Stallions...
A fungus was isolated from the skin of an Otaria byronia and water pool in which animal kept. It formed creamy colonies with soft texture on Dixon agar grew well without supplements long-chain fatty acids. Cells were ovoid to cylindrical shape, budded a broad base, divided at same location. Thus, isolate identified as M. pachydermatis. We compared this very rare marine mammal four strains pachydermatis using freeze-etching electron-microscopy technique. The cells showed characteristic...
In oral endoscopy, linked color imaging (LCI) detects atrophic border and gastric mucosal diseases better than white light (WLI), but its usefulness in transnasal endoscopy has not been fully investigated. Here, we retrospectively compared WLI LCI using the L*a*b* space images from 57 patients aged ≥20 years who had undergone as part of a health check-up May 2016 to January 2017. We measured differences at atrophic/non-atrophic fundic/pyloric borders. Gastritis severity scored Kyoto...
In the present study, authors examined association between gastric bacterial infection and endoscopic findings in
Abstract Helicobacter pylori eradication therapy reduces the risk of gastric cancer. However, it is unclear whether severity factors for cancer such as atrophy and intestinal metaplasia are reduced after in long term. We aimed to study long-term changes endoscopic up 20 years post-eradication. The gastritis according Kyoto Classification Gastritis 167 patients was retrospectively evaluated over an average follow-up 15.7 years. A significant improvement mean total score (4.36 ± 1.66 2.69...
The situation of Helicobacter pylori eradication therapy has been changing over time, owing to increases in antimicrobial-resistant strains, lifestyle improvements, and changes indications for eradication. In Japan, is now available all H. pylori-positive patients under the medical insurance system, potassium-competitive acid blocker vonoprazan used from 2015. Recently, with aging society, opportunities provide elderly are increasing, but current status effectiveness remains unclear....
The primer pheromone is responsible for the "male effects" in goats and produced sebaceous glands testosterone−dependently.In present study, responses of obtained from head rump regions castrated were examined by our bioassay system after testosterone treatment to demonstrate presence regional differences production male goats.The resulted marked development induction bioactivity region goats.On contrary, this brought neither nor region.The increased immunoreactivities androgen...
Previously we showed that the primer pheromone responsible for "male effect" was produced in specific skin regions of castrated male goats by androgen treatments. In present study, examined whether can also induce production effect female goats. Capsules containing dihydrotestosterone (DHT) or testosterone (T) were subcutaneously implanted into six ovariectomized (OVX) 28 days. Small samples collected from head and rump regions, activity their ether extracts using a bioassay monitors...