A5039005758- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Inflammatory Bowel Disease
- Gallbladder and Bile Duct Disorders
- Colorectal Cancer Screening and Detection
- Diverticular Disease and Complications
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Microscopic Colitis
- Pharmacological Effects of Natural Compounds
- Pediatric Hepatobiliary Diseases and Treatments
- Metabolomics and Mass Spectrometry Studies
- Biliary and Gastrointestinal Fistulas
- Intestinal Malrotation and Obstruction Disorders
- Polymer composites and self-healing
- Liver Diseases and Immunity
- Galectins and Cancer Biology
- Pressure Ulcer Prevention and Management
- Infection Control and Ventilation
- Hepatitis B Virus Studies
Tokyo Medical University
2016-2024
Tokyo Medical University Hospital
2019-2024
Kurashiki Central Hospital
2022-2023
National Cancer Center Hospital East
2022
Tokyo Rosai Hospital
1980-2016
Niigata University
2015
Kyushu University
2009
New Technology (Israel)
2003
Abstract Background Map‐like redness is a newly identified endoscopic risk factor for gastric cancer in patients who received Helicobacter pylori eradication therapy. However, the incidence rate of map‐like eradication, and factors development remain unclear. We hence aimed to investigate at 1‐year post H. evaluated its associations with relation condition. Materials Methods Endoscopic severity gastritis were retrospectively according Kyoto Classification Gastritis had undergone endoscopy...
A new image-enhanced endoscopy method called texture and colour enhancement imaging (TXI) enhances brightness, surface irregularities, subtle changes in endoscopic images. However, it is unclear whether TXI narrow-band (NBI) with third-generation high-vision transnasal ultrathin are advantageous over white-light (WLI) for detecting atrophy, intestinal metaplasia, map-like redness gastric cancer. We investigated to compare the efficacy evaluation of gastritis between NBI clarified compared...
Abstract We evaluated whether texture and color enhancement imaging (TXI) using a high-definition ultrathin transnasal endoscope (UTE) improves the visibility of early gastric cancer (EGC) compared with white-light (WLI). This study included 31 EGCs observed by TXI mode 2 UTE prior to endoscopic submucosal dissection. The first outcome was compare differences based on Commission Internationale de l’Eclairage L*a*b* space between surrounding mucosa WLI (objective appearance EGC). second...
Underwater endoscopic submucosal dissection (U-ESD) is a recently developed procedure that has the potential to prevent post-ESD coagulation syndrome (PECS) owing its heat-sink effect. We aimed clarify whether U-ESD decreases incidence of PECS compared with conventional ESD (C-ESD).A total 205 patients who underwent colorectal (C-ESD: 125; U-ESD: 80) were analyzed. Propensity score matching analysis was performed adjust for patient backgrounds. Ten C-ESD and two muscle damage or perforation...
Background/Aims: Recently, postendoscopic submucosal dissection electrocoagulation syndrome (PEECS) has attracted attention. However, the criteria for computed tomography (CT) scanning following esophageal endoscopic (ESD) are unclear. In this study, we aimed to identify predictive factors of PEECS and usefulness CT after ESD. Methods: A total 245 lesions in 223 patients who underwent ESD between February 2008 October 2018 were retrospectively analyzed. Patients with double cancers, those...
As the high mortality rate of gastric cancer (GC) is due to delayed diagnosis, early detection vital for improved patient outcomes. Metabolic deregulation plays an important role in GC. Although various metabolite-level biomarkers have been assessed, there still no unified method. We conducted a plasma metabolome study assess metabolites that may distinguish GC samples from non-GC samples.Blood were collected 72 patients and 29 control participants (non-GC group) at Tokyo Medical University...
Objective Acute hemorrhagic rectal ulcer (AHRU) is characterized by sudden, painless, and massive bleeding from ulcers. To date, few studies have analyzed the risk factors for AHRU rebleeding. In this study, we clarified of rebleeding after initial hemostasis through a multicenter study. Methods A total 149 patients diagnosed with between January 2015 May 2020 at 3 medical centers were enrolled. We retrospectively investigated following factors: age, sex, body mass index (BMI), performance...
Hybrid endoscopic submucosal dissection (ESD), in which an incision is made around a lesion and snaring performed after dissection, has some advantages colorectal surgery, including shorter procedure time preventing perforation. However, its value for rescue resection difficult ESD cases remains unclear. This study evaluated the utility of hybrid (RH-ESD).We divided 364 procedures into conventional group (C-ESD, n=260), scheduled (SH-ESD, n=69), RH-ESD (n=35) compared their clinical...
With the increase in elderly population, we are witnessing an rate of patients with underlying diseases and those under treatment antithrombotic drugs.In this study, compared outcomes endoscopic submucosal dissection (ESD) other parameters following 3 groups: super-elderly, elderly, nonelderly.Compared groups, super-elderly group showed a significantly higher incidence (P < .05). However, observed no significant difference curative resection or complications among groups. ESD is relatively...
To investigate the functional connectivity, evoked potentials by stimulating at motor cortex, posterior parietal and cerebellum transcranial magnetic stimulation (TMS) were measured. It is difficult to measure electroencephalograph (EEG) because of large artifact induced pulse. We used an EEG measurement system with sample-and-hold circuit independent component analysis eliminate electromagnetic interaction emitted from TMS. was possible signals all electrodes over head within 10 ms after...
Situs inversus totalis (SIT) is defined as the complete mirror-image transposition of thoracic and abdominal viscera. It a relatively rare congenital anomaly with an incidence approximately 1 per 4000 to 8000 persons.1Iwamura T. Shibata N. Haraguchi Y. et al.Synchronous double cancer stomach rectum situs polysplenia syndrome.J Clin Gastroenterol. 2001; 33: 148-153Crossref PubMed Scopus (48) Google Scholar Endoscopic submucosal dissection (ESD) widely performed treatment for early gastric...
A 58-year-old Japanese woman came to our institution because of leg edema and abdominal distention. She had developed acute pancreatitis 5 times in the past 3 years. Dilation bile duct main pancreatic without obstruction was observed on computed tomography magnetic resonance cholangiopancreatography. The presence Strongyloides stercoralis highly suspected from biopsy sample duodenal papilla. Polymerase chain reaction amplification sequencing small subunit rDNA paraffin-embedded specimens...
The prevalence of chronic constipation in Japan is increasing, and presently almost 1 5 people. Because common, especially older patients, to avoid adverse events polypharmacy, simple treatments at low doses are generally desired. Although the chloride channel activator lubiprostone candidate drug that may solve these problems, factors associated with long-term efficacy monotherapy for treatment-naive patients remain unclear. We here retrospectively investigated clinical characteristics who...
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We read with great interest the original article written by Nishino et al.Their retrospective study was performed univariate and multivariate logistic regression analyses, demonstrating that risk factors of portal hypertensive gastropathy (PHG) were existence esophageal varices, splenomegaly, severe liver cirrhosis (LC), etiology, absence atrophic gastritis (1).In Japan, there have been no reports clarifying frequency PHG, onset factors, prognosis, or relationship Helicobacter pylori...
Abstract Background 5-Aminosalicylic acid (5-ASA) is effective for ulcerative colitis (UC), yet several patients exhibit intolerance to this medication. Although biologics and immunomodulators are often employed in cases of 5-ASA UC, reports on their induction rates effectiveness sparse. This study aims ascertain the proportion therapeutic agents refractory UC evaluate efficacy intolerant 5-ASA. Methods We conducted a retrospective chart review 182 consecutive treated at our tertiary...
Abstract Background This study evaluated the association between risk factors and prognosis for metachronous esophageal squamous cell carcinoma (ESCC) after endoscopic resection (ER) of cancer in older patients. Methods We conducted a retrospective observational 127 patients with ESCC who underwent ER from 2015 to 2020. Patients were classified as non-older (≤ 64 years), early (65–74 late (≥ 75 years). analyzed associated poor overall survival using multivariate Cox regression analysis. A...
This paper tried to develop the optimum procedure for microencapsulating water soluble solid powder with thermal responsible material by melting dispersion cooling method. Sodium hydrogen carbonate was adopted as a instead of carbon dioxide gas. The shell composed olefin wax and α-tocopherol. In experiment, concentration oil surfactant species were changed. treated in aqueous solution dissolving form finer sodium increase content. microencapsulation efficiency could be increased considerably...
This study aimed to prevent the infection risk of environmental contamination by feces during endoscopic procedures. We evaluated effect coronavirus disease 2019 (COVID-19) on gastrointestinal tract using fecal polymerase chain reaction (PCR) and examined factors affecting procedures, develop prevention strategies.This single-center prospective observational enrolled 32 patients diagnosed with COVID-19 at Tokyo Medical University Hospital between January December 2022. performed reverse...
Exposure of the muscle layer during endoscopic submucosal dissection (ESD) in esophagus can lead to complications such as fever and pain. Although closure with clips is widely used when perforation a major complication, its value exposed not perforated unclear. Data for 104 lesions patients who underwent esophageal ESD between 2008 2020 were retrospectively analyzed. Patients multiple tumors, those experienced procedure-related adverse events aspiration pneumonitis, ESD, or delayed bleeding,...