A5033187160- Analytical Chemistry and Sensors
- Glaucoma and retinal disorders
- Antibiotics Pharmacokinetics and Efficacy
- Parathyroid Disorders and Treatments
- Traditional Chinese Medicine Analysis
- Ocular Infections and Treatments
- Ocular Surface and Contact Lens
- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Chromatography
- Chromatography in Natural Products
- Ophthalmology and Visual Impairment Studies
- Analytical chemistry methods development
- Phytochemistry and Biological Activities
- Intraocular Surgery and Lenses
- Cynara cardunculus studies
- Phytochemistry and Bioactive Compounds
- Neuroscience and Neuropharmacology Research
- Retinal Diseases and Treatments
- Muscle and Compartmental Disorders
- Pharmacovigilance and Adverse Drug Reactions
- Pharmaceutical studies and practices
- Maternal Mental Health During Pregnancy and Postpartum
- Ginger and Zingiberaceae research
- Advanced Drug Delivery Systems
- Traumatic Ocular and Foreign Body Injuries
Eye & ENT Hospital of Fudan University
2009-2025
Fudan University
2006-2024
Accommodation is crucial for clear near vision and predominantly affected by presbyopia. The ability to modulate accommodative function with eye drops could offer a pharmacological approach manage To investigate the effects of different concentrations pilocarpine on ocular accommodation in young volunteers. In this prospective study, healthy volunteers mild or moderate myopia corrected visual acuity no less than 20/20 were recruited. Participants underwent four visits baselining...
To validate the hypothesis proposed by previous studies, which suggests that NSAID use may elevate Klotho levels. We conducted a cross-sectional study involving 11,626 adults from National Health and Nutrition Examination Survey (NHANES) 2007-2016. Multivariable linear regression propensity score analysis were employed to evaluate association between serum Additionally, subgroup analyses performed assess consistency of this relationship across various subgroups. demonstrated was negatively...
Objective: This study aimed to investigate the etiology, pathogens, antibiotic susceptibility, treatments, and factors influencing visual prognosis of pediatric post-traumatic endophthalmitis (PTE) provide valuable insights for clinical diagnosis treatment. Results: A total 301 children were included, with 142 (47.2%) cultures yielding positive results. Gram-positive cocci predominant pathogens (71.1%), high sensitivity vancomycin (95.4%). Pars plana vitrectomy (PPV) was performed in 216...
A simple, rapid, and accurate stability-indicating reverse phase liquid chromatographic method was developed validated for the simultaneous determination of pheniramine maleate naphazoline hydrochloride in bulk drugs pharmaceutical formulations. Optimum separations among maleate, stress-induced degradation products have been achieved within 10 minutes by using an Agilent zorbax eclipse XDB C18 column (150 mm × 4.6 mm, 5 μm) as stationary with a mobile consisted mM phosphate buffer pH 2.8...
Abstract Saxitoxin, which is one of the most typical paralytic shellfish poisoning toxins, ranks highest intoxication rate marine biological cases globally. Efficient clean‐up and extraction saxitoxin from complex matrices are imperative for analysis concentration monitoring toxin when correlative happen. Herein, l ‐cysteine‐modified magnetic microspheres based on metal‐organic coordination were synthesized by a facile approach applied solid‐phase rat plasma samples before liquid...
In this study, a novel method based on high performance liquid chromatography (HPLC) following infrared-assisted extraction (IRAE) has been developed for the determination of liquiritin and glycyrrhizic acid in licorice root. Liquiritin are important active components present (Glycyrrhiza uralensis Fisch). Four factors, solvent, solid/liquid ratio, illumination time, distance between infrared lamp round-bottom flask, were investigated to optimize from Under optimum conditions, i.e. 50%...
Klotho is a protein with various biological functions, including anti-aging effects. Although research suggests plays key role in auditory function, the relationship between serum levels and high-frequency hearing loss (HFHL) older adults remains unclear.
A simple, rapid and accurate stability-indicating reverse phase high performance liquid chromatography (RP-HPLC) was developed validated for the determination of brimonidine tartrate in tartrate/poly(2-hydroxyethyl methacrylate) (BRI/PHEMA) drug delivery contact lenses pharmaceutical formulations. Optimum chromatographic conditions separating from other impurities leaching liquor BRI/PHEMA or formulations have been achieved by using a Diamonsil C18 column (150 mm × 4.6 mm, 5 μm) as...
Angoroside C, cinnamic acid, and harpagoside are bioactive constituents in Scrophularia ningpoensis. Currently, an infrared-assisted extraction (IRAE) method coupled with high-performance liquid chromatography ultraviolet detection (HPLC-UV) for the analysis of this plant is lacking. A based on HPLC following IRAE has been developed quantifying angoroside Four main factors, namely, solvent, solid/liquid ratio, illumination time, distance between infrared lamp round-bottom flask, were...
Cinnamic acid and harpagoside are important active components present in Scrophularia ningpoensis, which has been used in the treatment of several diseases such as pharyngalgia. In study, a novel method based on high performance liquid chromatography (HPLC) following microwave-assisted extraction (MAE) was developed for determination cinnamic traditional Chinese medicine (TCM) of S. ningpoensis. Effective chromatographic separation achieved C18 column at detection wavelength 278 nm....
<b><i>Background/Aims:</i></b> We have undertaken this study to investigate the feasibility of topical application radioprotective compound WR-2721 buccal mucosa. <b><i>Methods:</i></b> Saliva samples were collected from 5 volunteers and reconstituted in 3 amifostine solutions. Measurements WR-1065 contents performed at 6 different time points. Young-adult guinea pigs topically administered 50 100 mg each At 0, 15 30 min after application,...
Acute post-cataract surgery endophthalmitis (APSE) is a serious vision-threatening complication of cataract surgery. Analysis the management and prognosis in cases APSE may provide better guidance for future treatment. Fifty-six patients (56 eyes) diagnosed with between 2013 2022 were retrospectively reviewed. The incidence rate was 0.020% (95% CI: 0.011–0.029%). Intraocular cultures positive 18 (32.1%) cases, 21 organisms isolated. Coagulase-negative staphylococci predominant isolate...