A5101978192- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Mass Spectrometry Techniques and Applications
- Water Quality Monitoring and Analysis
- Natural product bioactivities and synthesis
- Advanced Proteomics Techniques and Applications
- Marine and coastal ecosystems
- Advanced Chemical Sensor Technologies
- Metabolomics and Mass Spectrometry Studies
- Pharmacological Effects of Natural Compounds
- High-pressure geophysics and materials
- Geological and Geochemical Analysis
- earthquake and tectonic studies
- Toxic Organic Pollutants Impact
- Analytical Methods in Pharmaceuticals
- Traditional Chinese Medicine Analysis
- Mercury impact and mitigation studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Phytoestrogen effects and research
- Medicinal Plant Pharmacodynamics Research
- Synthesis and Biological Evaluation
- Chemical Analysis and Environmental Impact
- Plant biochemistry and biosynthesis
- Ginseng Biological Effects and Applications
- Hormonal and reproductive studies
Shandong University of Traditional Chinese Medicine
2012-2025
Health Canada
2020-2025
Ministry of Agriculture and Rural Affairs
2024
Institute of Biophysics
2012-2024
Chinese Academy of Sciences
2008-2024
University of Chinese Academy of Sciences
2020-2021
Nanjing University
2014-2021
Fudan University
2006-2021
Pudong Medical Center
2019-2021
State Key Laboratory of Pollution Control and Resource Reuse
2014-2021
Dissolved organic matter (DOM) in municipal wastewater was mainly characterized using high-performance liquid chromatography (HPLC) and size exclusion (HPSEC) with multi-excitation/emission fluorescence scan. Meanwhile, excitation–emission-matrix combined parallel factor analysis (EEM-PARAFAC) also applied. Compared fingerprints, the EEM-PARAFAC model could not reflect variety of DOM species similar but different physicochemical properties. The results showed that protein-like were variable...
Holistic analysis of lipids is becoming increasingly popular in the life sciences. Recently, several interesting, mass spectrometry-based studies have been conducted, especially plant biology. However, while great advancements made we are still far from detecting all species an organism. In this study developed ultra performance liquid chromatography-based method using a high resolution, accurate mass, spectrometer for comprehensive profiling more than 260 polar and non-polar Arabidopsis...
Over the past few years, mass spectrometry has emerged as a technology to complement and potentially replace standard immunoassays in routine clinical core laboratories. Application of protein peptide measurement can provide advantages including high sensitivity, ability multiplex analytes, specificity at amino acid sequence level. In our previous study, we demonstrated excellent reproducibility spectrometry-selective reaction monitoring (MS-SRM) assays when applying standardized operating...
A convenient, effective, and low-cost method was developed for the determination of 38 pharmaceuticals personal care products (PPCPs), including 19 antibiotics in surface water samples by lyophilization combined with liquid chromatography-tandem quadrupole mass spectrometry (LC-MS/MS). The components extraction solvent, volume sample, solvent were successively optimized. analytes 80 mL concentrated lyophilization, eluted effectively 2 acetonitrile, acetone, ultrapure water. detection limits...
A novel nonchromatographic speciation technique for ultratrace methylmercury in biological materials was developed by flow injection microcolumn displacement sorption preconcentration and separation coupled on-line with electrothermal atomic absorption spectrometry (ETAAS). In the technique, Cu(II) first complexed diethyldithiocarbamate (DDTC), resultant Cu−DDTC presorbed onto a packed sorbent from cigarette filter. Selective of (MeHg) presence Hg(II), ethylmercury (EtHg), phenylmercury...
Straw return improves soil carbon pool and dissolved organic matter (DOM) characteristics in black soil. Optimal straw rate is the key to promoting practices farmland Northeast China. The experiment was conducted at Science Technology Park of China Grain Storage Northern Corporation NenJiang, Heilongjiang Province, 0 kg hm−2, 3000 4500 9000 hm−2. In seventh year experiment, we used three-dimensional excitation-emission matrices combined with Parallel Factor analysis characterize fluorescence...
ABSTRACT Liu Shenqu (Massa Medicata Fermentata [MMF]) is a natural fermented product of flour (and/or wheat bran) and five medicinal herbs, Prunus armeniaca , Vigna umbellata Artemisia annua Polygonum hydropiper Xanthium strumarium . Unprocessed, stir‐fried, charred MMF has been used therapeutically in China for over thousand years to treat conditions such as dyspepsia, abdominal distension, diarrhea. Variations quantities, fermentation conditions, processing procedures across different...
Rationale Limonoids, characterized by a triterpenoid skeleton with furan ring, are unique secondary metabolites widely distributed in the families of Rutaceae , particularly Citrus species and Meliaceae. Studies on health benefits have demonstrated that limonoids range biological activities. Dietary intake citrus may provide protective effect against onset various cancers other xenobiotic related diseases. However, few studies about metabolic profiles been carried out. Methods The objectives...
Aromatic steroids including monoaromatic (MAS) and triaromatic (TAS) are a series of naphthenoaromatic hydrocarbons, which consist mixed structures aromatic saturated 6-carbon or 5-carbon rings. Although these in relatively low concentration oils, their specific fingerprints high weathering resistance make them desirable biomarkers for the characterization, correlation, differentiation, source identification environmental forensic investigations oil spills. This study presents quantitative...
A simple and sensitive high performance liquid chromatography with fluorescence detection (HPLC–FD) has been developed for simultaneous quantification of doxorubicin (DOX) its dipeptide conjugate prodrug (PDOX) in mice plasma. The chromatographic separation was carried out on an Amethyst C18–H column gradient mobile phase 0.1% formic acid acetonitrile at a flow rate 1.0 mL/min. excitation emission wavelengths were set 490 550 nm, respectively. method comprehensively validated. limits low up...
Abstract A coupling of capillary RP LC as the first dimension with CIEF second followed by MALDI‐MS identification was demonstrated. Based on 2‐D separation system developed our group ( Electrophoresis 2003, 24 , 3289–3295), this paper focused incorporating tryptic digestion into top‐down proteomics methodology, retaining benefits method. Hydrophobic layer packing‐material C18 coated SE‐30 MALDI‐target surface used to permit fractions be easily concentrated and free ampholytes using...
As a large group of stable existing organofluorine compounds widely present in the environment, perfluorochemicals (PFCs) could pose potential adverse effects on human health.