As Ukraine struggles with the education of healthcare professionals due to war, we aimed identify specific effects war on medical education, resulting needs, and expected consequences for schools, faculty, staff, students, system.In October November 2022, performed a survey staff schools in conducted semi-structured interviews faculty leaders (i.e., rectors, vice-rectors). We descriptive analysis survey's closed-ended questions. The included open-ended questions about war-related...

The healthcare system is under constant pressure from a growing and aging population, escalating costs, limited resources increasing demand. Achieving the triple aim of – improving care, health reducing costs requires innovation. According to World Health Organization (WHO), innovation development new or improved policies, systems, products technologies, services delivery methods that improve people’s health, with particular focus on needs vulnerable populations. innovations have both...

Abstract Background As Ukraine struggles with the education of healthcare professionals due to war, we aimed identify specific effects war on medical education, resulting needs, and expected consequences for schools, faculty, staff, students, system. Methods In October November 2022, performed a survey staff schools in conducted semi-structured interviews faculty leaders (i.e., rectors, vice-rectors). We descriptive analysis closed-ended questions thematic open-ended interviews. Results...

Objective — to investigate and improve methodological approaches of ecological upgrading in education; determine the formation attitude towards culture among medical students.Material methods. Modern data scientific achievements on topic were analyzed processed within contemporary literature. The investigation was held 2020. 160 students their 1st 2nd years, who study at Bukovinian State Medical University, Master’s program, participated it. We applied such methods as observation,...

The aim: To study the clinical and spirographic features persistence of bronchial asthma in schoolchildren against background alternative daily doses inhaled corticosteroids to increase effectiveness anti-inflammatory therapy for this disease. Materials methods: A complete comprehensive clinical-paraclinical examination 65 with persistent was conducted. According average dose (ICS) patients were divided into two groups. first (I) group consisted 46 children who received ICS regimen...

Establishing communication between the student and teacher by improving feedback allows to strengthen cooperation learning outcomes, be able respond change style of presenting information, according needs students, hones

Background. Renal ischemia/reperfusion (I/R) accounts for a significant number of acute kidney injury cases in humans. It calls forth the search novel therapies able to prevent progression and improve prognosis by protection tubular cells restoration function. Objective. To study histopathological changes kidneys rats with I/R estimation renoprotective potential organospecific peptides — peptide complex (PKC), synthetic AED, EDL AEDG. Methods. The was conducted on 42 non-linear rats. modeled...

Background. Respiratory morbidity is the most frequent cause for children consulting a doctor, accounting about one-quarter of primary care consultations. The current research aimed to analyze clinical and paraclinical features community-acquired pneumonia (CAP) with comorbid chronic tonsillitis in assess prognostic value proposed diagnostic procedures optimize management patients. Materials methods. study was conducted at Pulmonology Allergology Infectious Department Municipal Medical...

Despite significant advances in drug therapy and improvements renal replacement therapy, mortality rate of acute kidney injury (AKI) continuously increases is about 25-70 %. Ischemia-reperfusion AKI not an exception with its multifactorial pathogenesis rapid progressive development, usually resulting from trauma, sepsis, transplantation, or influence toxic substances. For this reason, drugs potent cytoprotective antioxidant activity – ademetionine glutathione have drawn our attention as...

Aminoglycosides are effective antibiotics, but their accumulation in kidney cortex causes nephrotoxic effects 20-30% of patients, which significantly limits use. For this reason, search for the new therapies aimed at prevention gentamicin-induced acute injury (AKI) is highly relevant. Thus, objective our research was to study functional and histopathological changes kidneys rats with AKI, estimate renoprotective potential pineal hormone melatonin, possesses antioxidant, anti-inflammatory...

Aim. To study the nephroprotective effect of sulfur-containing amino acids (ademetionine, taurine and glutathione) on different models acute kidney injury (AKI) by integral index survival rate animals.Materials methods. The experiments were performed 105 non-linear mature white laboratory rats 35 mice. drugs studied – ademetionine (Geptral, Abbott SpA, Italy) in dose 20 mg/kg, glutathione (TAD 600, Biomedica Foscama, 30 mg/kg (Sigma-Aldrich, USA) 100 injected intraperitoneally 3-7 days...

Derivatives of sulfur-containing aminoacids (ademetionin, taurine and glutathione) selected for the experimental studies are used in various fields practical medicine due to their multifaceted pleiotropic effects. The study renal effects conditions physiological norm makes it possible expand supplement pharmacological characteristics, forms basis further nephroprotective potential pathology.Aim. To effect amino acid derivatives (ademetionine, andglutathione) on morphofunctional state rat...

In experiments on laboratory nonlinear white mature rats, the effect of melatonin (5 mg/kg) morphofunctional state kidneys under conditions cisplatin-induced acute kidney injury was studied.It found that single administration cisplatin at a dose 6 mg/kg causes necrosis and disseminated degenerative changes tubular cells with development oliguric form toxic nephropathy, which is accompanied by decrease in diuresis 2.9 times, reduction glomerular filtration rate 5 an increase plasma creatinine...

The effect of certain statins with different lipophilicity (atorvastatin (ATO), lovastatin (LOV), simvastatin (SIM)) on renal function apparently healthy rats at a conventionally effective dose 20 mg/kg was established.As it has been found in our experiments the 7 th day administration there only slight increase urine output along moderate growth glomerular filtration rate (GFR) and decrease excretion sodium ions protein while maintaining mechanisms intrarenal autoregulation.Renotropic...

The article considers the relevance of curricular integration as an essentialpart medical education, which allows supplementing content one disciplinewith knowledge from another, and substantiating possibility a comprehensivesolution challenges practice by wide acquiredinformation various disciplines. Pharmacology integrated science combinespreclinical clinical subjects promotes acquisition professional knowledgeand skills.The paper establishes characteristics place different types...

INTRODUCTION: Melatonin is a promising therapeutic agent due to its multiple beneficial effects, wide availability and relatively high safety. As melatonin acts as chronobiotic agent, adequate production by the pineal gland allows for adaptation environmental changes, while disturbances in secretion are associated with health disorders. The renoprotective effect of exogenous was established on different experimental models acute kidney injury (AKI), influence altered activity efficacy...