The results of screening 2-(benzoyilamino)(1-R-2-oxoindolin-3-ylidene)acetic acid derivatives on the antihypoxic activity are presented in article. It has been determined that under conditions acute hypоbaric hypoxia compounds 4, 14 and 15 have shown increase integral index substances – overall lifetime animals at “high-altitude plateau”. However, mortality rate reached 20% for compound it significantly exceeded control data. At same time, by its increased 150% compared to data, but effect...

Introduction: The rapid development of perinatal gynecology requires from the anatomists comprehensive studies patterns prenatal morphogenesis and topographic anatomical relationships female reproductive organs in human fetuses different age groups. aim: To study formation vaginal topography period ontogenesis. Materials methods: has been conducted based on 23 series histological topographic-anatomical sections prefetuses aged 9-12 weeks with 31.0-80.0 mm crown-rump length (CRL) 83 specimens...

The effect of three statins (atorvastatin, lovastatin, simvastatin) on the renal function under conditions experimental acute failure in rats was studied. relatively effective doses were found to possess most considerable renoprotective properties. All established cause restoration functional activity kidneys rhabdomyolytic at various doses, but with dose 20 mg/kg they showed significant improvement key indices kidney function: an increase diuresis by average 32% and glomerular filtration...

Congenital abnormalities occur in 2-3% of all children and about 1% have hereditary syndromes or multiple malformations. About 30% cases a cleft lip palate. Genetic factors such as chromosomal gene mutations cause 15% congenital abnormalities; exogenous environmental 10% defects; combination genetic (multifactorial inheritance) 20-25%; pregnancy causes 0.5-1% abnormalities. Craniofacial anomalies represent an important pediatric problem. They are among the leading infant mortality morbidity....

Aim. To study the influence of 2-benzamide-2-(2-oxoindolin-3-ylidene) acetic acid derivative ZNM on succinate dehydrogenase and lactate activity biochemical markers energy metabolism hypoxia in rats’ brain under acute hypobaric (AHH) normobaric hypercapnic (NHH), as well chronic (CHH).Materials methods. 80 white nonlinear mature male rats 180-200 g weight were used for research. AHH was modeled using flowing altitude chamber by stimulation effect of12000 m “ascending” rats. The kept at...

The influence of glutathione on the prooxidant-antioxidant balance in rats’ kidneys and blood under conditions rhabdomyolytic model acute kidney injury was studied experiment. It is observed that intraperitoneal administration glutathioneіn dose 30 mg/kg normalizes balance, confirmed by reduction lipid protein peroxidation intensity, normalization catalase peroxidase activity, SH-groups andceruloplasmin content.

Anatomie échographique foetale et paramètres morphométriques de l'humérus chez les foetus à 19-22 semaines gestationIntroduction.La biométrie est une méthode basée sur la mesure certaines parties anatomiques du différents stades grossesse.La croissance influencée par interaction complexe facteurs génétiques, héréditaires environnementaux.Une évaluation précise développement foetal nécessite connaissance l'anatomie foetale.La longueur des os tubulaires longs directement corrélée l'âge...

On the front abdominal wall, there is a section of vesico- umbilical triangle, which bounded on sides by arteries, and below bladder. In available sources scientifi c literature, practically no information patterns prenatal morphogenesis formation topography area triangle person. However, accurate knowledge constituent formations determines choice incision during operations provides theoretical explanation for occurrence various pathological conditions: umbilical, postoperative ventral...

Ultrasound screening is one of the most informative methods visualizing fetal development during pregnancy. During standard ultrasound examinations, length femur fetus measured. However, if any skeletal dysplasia or intrauterine growth retardation suspected, additional measurement other long tubular bones should be performed. The aim work was to investigate morphometric parameters lengths right and left tibia establish correlations between them corresponding fibula, lower limb crown rump...

The need to study anatomical and functional features of the hand is determined by tendency increase number injuries both among military personnel civilians who suff ered from hostilities in Ukraine.The aimed justify choice method analgesia region, taking into account topographic- pharmacological features.Material methods. A topographical justifi cation anesthesia has been carried out through comparison data existing practice guidelines for analgesia, considering modern conditions providing...

Assessment of the length long tubular bones fetus, including ulna and radius, is used in modern fetal anatomy to estimate gestational age fetus. In addition, assessment skeleton important for detection skeletal disproportion, namely achondroplasia hypochondroplasia. Congenital defects can also be diagnosed prenatally by ultrasound.Objective research. To determine morphometric parameters radius at 19-22 weeks gestation.Materials methods. structures we an imaging method such as ultrasound...

Digital data of computer tomograms primary centers ossification in human fetuses can serve as age-normative intervals relevant for gynecologists, obstetricians, pediatricians, and diagnosticians during screening ultrasound examinations. Aim - to clarify the timing emergence dynamics further development bone deposits estimating fetal age diagnosis congenital malformations. Materials methods. The study was carried out on 32 series consecutive sagittal, frontal, horizontal sections embryos...

Nowadays, the assessment of length femur and humerus is preferred, which plays a key role in doubtful cases to determine age fetus second or third trimester intrauterine development. The aim study was evaluate characteristics ossification right left humeral diaphysis fetuses at 20-32 weeks gestation for assessing fetus. Materials methods. Plain radiographs computed tomography scans 52 human were analyzed fetuses. results statistically using Excel. are presented as statistical means with...

One of the urgent tasks modern medicine is prevention brain damage during human fetal period and creation conditions that ensure proper development. Objective research. To find out features early morphogenesis central nervous system in embryonic pre-fetal periods ontogenesis. Methods. The study stages formation spinal cord was carried on 14 embryos 12 fetuses with 4.5-20.0 mm parietal-caudal length (PCL) by methods microscopy, three-dimensional computer reconstruction, morphometry,...

In the treatment of wounded people with gunshot osteomyelitis, muscle plastic on leg was widely used. Objective. To study intramuscular distribution nerves in extensor digitorum, ulnaris, carpi and digiti minimi, which, comparison branching arterial vessels, can determine rational methods cutting flaps from these muscles. Material methods. Clarification peculiarities arteries superficial muscles posterior compartment forearm carried out 42 preparations human fetuses 4-10 months using...